Search Results - "LEE, JUNG YOUNG"

Therapeutic applications of compounds in the Magnolia family by Lee, Young-Jung, Lee, Yoot Mo, Lee, Chong-Kil, Jung, Jae Kyung, Han, Sang Bae, Hong, Jin Tae

“…The bark and/or seed cones of the Magnolia tree have been used in traditional herbal medicines in Korea, China and Japan. Bioactive ingredients such as…”
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Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties by Lee, Young-Jung, Choi, Dong-Young, Yun, Yeo-Pyo, Han, Sang Bae, Oh, Ki-Wan, Hong, Jin Tae

“…Neuroinflammation has been known to play a critical role in the pathogenesis of Alzheimer's disease (AD) through amyloidogenesis. In a previous study, we found…”
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Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models by Lee, Young-Jung, Choi, Dong-Young, Choi, Im Seop, Kim, Ki Ho, Kim, Young Hee, Kim, Hwan Mook, Lee, Kiho, Cho, Won Gil, Jung, Jea Kyung, Han, Sang Bae, Han, Jin-Yi, Nam, Sang-Yoon, Yun, Young Won, Jeong, Jae Hwang, Oh, Ki-Wan, Hong, Jin Tae

“…Neuroinflammation is important in the pathogenesis and progression of Alzheimer disease (AD). Previously, we demonstrated that lipopolysaccharide (LPS)-induced…”
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Gastrokine 1 inhibits gastric cancer cell migration and invasion by downregulating RhoA expression by Yoon, Jung Hwan, Choi, Won Suk, Kim, Olga, Choi, Byung Joon, Nam, Suk Woo, Lee, Jung Young, Park, Won Sang

“…Background We investigated whether GKN1, a gastric tumor suppressor, contributes to the progression of gastric cancer by regulating RhoA expression. Methods We…”
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PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas by Lee, Jong Woo, Soung, Young Hwa, Kim, Su Young, Lee, Hae Woo, Park, Won Sang, Nam, Suk Woo, Kim, Sang Ho, Lee, Jung Young, Yoo, Nam Jin, Lee, Sug Hyung

“…A recent report revealed that phosphoinositide-3-kinase, catalytic, alpha (PIK3CA) gene is somatically mutated in several types of human cancer, suggesting the…”
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Anti-SARS-CoV-2 Neutralizing Antibody Responses after Two Doses of ChAdOx1 nCoV-19 vaccine (AZD1222) in Healthcare Workers by Lim, Sera, Lee, Yuil, Kim, Dong Wan, Park, Won Sang, Yoon, Jung Hwan, Lee, Jung Young

“…The kinetics of neutralizing antibodies against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) play an important role in evaluating vaccine…”
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Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer's disease mice model by Jin, Peng, Kim, Jin-A, Choi, Dong-Young, Lee, Young-Jung, Jung, Heon Sang, Hong, Jin Tae

“…Alzheimer's disease (AD) is pathologically characterized by excessive accumulation of amyloid-beta (Aβ) fibrils within the brain and activation of astrocytes…”
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Somatic Mutations of EGFR Gene in Squamous Cell Carcinoma of the Head and Neck by Lee, Jong Woo, Soung, Young Hwa, Kim, Su Young, Nam, Hyo Kyung, Park, Won Sang, Nam, Suk Woo, Kim, Min Sik, Sun, Dong Il, Lee, Youn Soo, Jang, Ja June, Lee, Jung Young, Yoo, Nam Jin, Lee, Sug Hyung

“…Purpose: Recently, the kinase domain mutations of epidermal growth factor receptor ( EGFR ) gene have been identified in non–small-cell lung cancer, and these…”
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Ethanol Extract of Magnolia officinalis Prevents Lipopolysaccharide‐Induced Memory Deficiency via Its Antineuroinflammatory and Antiamyloidogenic Effects by Lee, Young‐Jung, Choi, Dong‐Young, Yun, Yeo‐Pyo, Han, Sang Bae, Kim, Hwan Mook, Lee, Kiho, Choi, Seok Hwa, Yang, Mhan‐Pyo, Jeon, Hyun Soo, Jeong, Jea‐Hwang, Oh, Ki‐Wan, Hong, Jin Tae

“…Magnolia bark contains several compounds such as magnolol, honokiol, 4‐O‐methylhonokiol, obovatol, and other neolignan compounds. These compounds have been…”
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Heterodimeric interaction between GKN2 and TFF1 entails synergistic antiproliferative and pro-apoptotic effects on gastric cancer cells by Kim, Olga, Yoon, Jung Hwan, Choi, Won Suk, Ashktorab, Hassan, Smoot, Duane T., Nam, Suk Woo, Lee, Jung Young, Park, Won Sang

“…Background GKN2 and TFF1 form a heterodimer that is only generated in the mucus-secreting cells of the normal stomach. The formation of this heterodimer is…”
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The sensitivity and specificity of the Falls Efficacy Scale and the Activities-specific Balance Confidence Scale for hemiplegic stroke patients by Park, Eun-Young, Lee, Young-Jung, Choi, Yoo-Im

“…[Purpose] This study attempted to investigate the sensitivity and specificity of the Falls Efficacy Scale (FES) and the Activities-Specific Balance Confidence…”
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Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells by Lee, Young-Jung, Choi, Dong-Young, Choi, Im Seup, Han, Jin-Yi, Jeong, Heon-Sang, Han, Sang Bae, Oh, Ki-Wan, Hong, Jin Tae

“…Amyloidogenesis is linked to neuroinflammation. The tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal, possesses…”
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Gastrokine 1 protein is a potential theragnostic target for gastric cancer by Yoon, Jung Hwan, Ham, In-Hye, Kim, Olga, Ashktorab, Hassan, Smoot, Duane T., Nam, Suk Woo, Lee, Jung Young, Hur, Hoon, Park, Won Sang

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CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas by YOUNG HWA SOUNG, JONG WOO LEE, SU YOUNG KIM, JANG, Jin, YONG GYU PARK, WON SANG PARK, SUK WOO NAM, JUNG YOUNG LEE, NAM JIN YOO, SUG HYUNG LEE

“…Several lines of evidence indicate that deregulation of apoptosis is involved in the mechanisms of cancer development. Caspase-8 activation plays a central…”
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Inhibitory Effect of Ethanol Extract of Magnolia officinalis on Memory Impairment and Amyloidogenesis in a Transgenic Mouse Model of Alzheimer's Disease via Regulating β-Secretase Activity by Lee, Young-Jung, Choi, Dong-Young, Han, Sang Bae, Kim, Young Hee, Kim, Ki Ho, Hwang, Bang Yeon, Kang, Jong-Koo, Lee, Beom Jun, Oh, Ki-Won, Hong, Jin Tae

“…Alzheimer's disease (AD) is the most common form of dementia and is characterized by deposition of amyloid beta (Aβ) in the brain. The components of the herb…”
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Gastrokine 1 inhibits gastrin-induced cell proliferation by Kim, Olga, Yoon, Jung Hwan, Choi, Won Suk, Ashktorab, Hassan, Smoot, Duane T., Nam, Suk Woo, Lee, Jung Young, Park, Won Sang

“…Background Gastrokine 1 (GKN1) acts as a gastric tumor suppressor. Here, we investigated whether GKN1 contributes to the maintenance of gastric mucosal…”
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A Noncanonical mu-1A-Binding Motif in the N Terminus of HIV-1 Nef Determines Its Ability To Downregulate Major Histocompatibility Complex Class I in T Lymphocytes by IIJIMA, Sayuki, LEE, Young-Jung, ODE, Hirotaka, AROLD, Stefan T, KIMURA, Nobuyuki, YOKOYAMA, Masaru, SATO, Hironori, TANAKA, Yasuhito, STREBEL, Klaus, AKARI, Hirofumi

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease by Choi, Dong-Young, Lee, Young-Jung, Hong, Jin Tae, Lee, Hwa-Jeong

“…Highlights ► We reviewed and summarized antioxidant and neuroprotective effects of selected polyphenols. ► Neuroprotection by the polyphenols is attributable…”
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BRAF and KRAS mutations in stomach cancer by Lee, Sug Hyung, Lee, Jong Woo, Soung, Young Hwa, Kim, Hong Sug, Park, Won Sang, Kim, Su Young, Lee, Jong Heun, Park, Jik Young, Cho, Yong Gu, Kim, Chang Jae, Nam, Suk Woo, Kim, Sang Ho, Lee, Jung Young, Yoo, Nam Jin

“…Ras proteins control signaling pathways that are key regulators of several aspects of normal cell growth and malignant transformation. BRAF, which encodes a…”
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Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR‐125a‐5p and MiR‐125b by Kim, Jeong Kyu, Noh, Ji Heon, Jung, Kwang Hwa, Eun, Jung Woo, Bae, Hyun Jin, Kim, Min Gyu, Chang, Young Gyoon, Shen, Qingyu, Park, Won Sang, Lee, Jung Young, Borlak, Jürgen, Nam, Suk Woo

“…Sirtuins are nicotinamide adenine dinucleotide oxidized form (NAD+)‐dependent deacetylases and function in cellular metabolism, stress resistance, and aging…”
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