Search Results - "LEE, Ha Na"
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Myc‐nick promotes efferocytosis through M2 macrophage polarization during resolution of inflammation
Published in The FASEB journal (01-10-2018)“…ABSTRACT A key event required for effective resolution of inflammation is efferocytosis, which is defined as phagocytic removal of apoptotic cells mostly by…”
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2
17-β estradiol exerts anti-inflammatory effects through activation of Nrf2 in mouse embryonic fibroblasts
Published in PloS one (23-08-2019)“…Several reports indicate crosstalk between the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and estrogen, which has a protective…”
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3
17β-Estradiol supplementation changes gut microbiota diversity in intact and colorectal cancer-induced ICR male mice
Published in Scientific reports (23-07-2020)“…The composition of the gut microbiota is influenced by sex hormones and colorectal cancer (CRC). Previously, we reported that 17β-estradiol (E2) inhibits…”
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4
Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice
Published in PLoS pathogens (10-12-2020)“…The neurodevelopmental defects associated with ZIKV infections early in pregnancy are well documented, however the potential defects and long-term consequences…”
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5
Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin
Published in Nature communications (16-05-2024)“…Lipid biosynthesis in the pathogen Mycobacterium tuberculosis depends on biotin for posttranslational modification of key enzymes. However, the mycobacterial…”
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6
Therapeutic potential of resolvins in the prevention and treatment of inflammatory disorders
Published in Biochemical pharmacology (15-11-2012)“…Acute inflammation, the primary response to harmful infection and injury, can be successfully completed through effective resolution and tissue repair…”
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7
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model
Published in Cancer letters (01-09-2022)“…17β-estradiol (E2) is known to have a protective effect in colorectal cancer (CRC); thus, E2 may be effective for cancer immunotherapy in CRC. The aim of this…”
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8
Resolvin D1 suppresses inflammation‐associated tumorigenesis in the colon by inhibiting IL‐6‐induced mitotic spindle abnormality
Published in The FASEB journal (01-05-2021)“…While failure in resolution of inflammation is considered to increase the risk of tumorigenesis, there is paucity of experimental as well as clinical evidence…”
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9
Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice
Published in eLife (03-02-2022)“…The outcome of an encounter with ( ) depends on the pathogen's ability to adapt to the variable immune pressures exerted by the host. Understanding this…”
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10
Pyrophosphate-Selective Fluorescent Chemosensor at Physiological pH: Formation of a Unique Excimer upon Addition of Pyrophosphate
Published in Journal of the American Chemical Society (04-04-2007)“…We report a new fluorescent chemosensor that displays an excellent selectivity for pyrophosphate over adenosine triphosphate or phosphate in 100% aqueous…”
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11
Evaluation of a New Chemiluminescent Immunoassay-Based Interferon-Gamma Release Assay for Detection of Latent Tuberculosis Infection
Published in Medicina (Kaunas, Lithuania) (27-09-2023)“…Background and Objectives: This study aimed to evaluate the performance of a new chemiluminescent immunoassay-based tuberculosis (TB) interferon-gamma release…”
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12
Neonatal Zika virus infection causes transient perineuronal net degradation
Published in Frontiers in cellular neuroscience (11-07-2023)“…Perineuronal nets (PNNs) form a specialized extracellular matrix that predominantly surrounds parvalbumin (PV)-expressing GABAergic inhibitory interneurons and…”
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13
Mycobacterial Regulatory Systems Involved in the Regulation of Gene Expression Under Respiration-Inhibitory Conditions
Published in The journal of microbiology (01-03-2023)“…Mycobacterium tuberculosis is the causative agent of tuberculosis. M. tuberculosis can survive in a dormant state within the granuloma, avoiding the…”
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14
Changes in Gut Microbiome upon Orchiectomy and Testosterone Administration in AOM/DSS-Induced Colon Cancer Mouse Model
Published in Cancer research and treatment (01-01-2023)“…Sex hormones are known to affect the gut microbiota. Previously, we reported that endogenous and exogenous testosterone are associated with colorectal cancer…”
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15
Regulation of the ahpC gene encoding alkyl hydroperoxide reductase in Mycobacterium smegmatis
Published in PloS one (03-11-2014)“…The ahpC (MSMEG_4891) gene encodes alkyl hydroperoxide reductase C in Mycobacterium smegmatis mc2155 and its expression is induced under oxidative stress…”
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16
Dendritic cells expressing immunoreceptor CD300f are critical for controlling chronic gut inflammation
Published in The Journal of clinical investigation (01-05-2017)“…Proinflammatory cytokine overproduction and excessive cell death, coupled with impaired clearance of apoptotic cells, have been implicated as causes of failure…”
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17
Potential Role of Heme Oxygenase-1 in the Resolution of Experimentally Induced Colitis through Regulation of Macrophage Polarization
Published in Gut and liver (15-03-2022)“…Heme oxygenase-1 (HO-1) plays a central role in cellular defense against inflammatory insults, and its induction in macrophages potentiates their efferocytic…”
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18
Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development
Published in Cancer research and treatment (01-04-2019)“…This study demonstrates that estradiol downregulates inflammation and inhibits colorectal cancer (CRC) development in azoxymethane/dextran sulfate sodium…”
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19
17β-Estradiol reduces inflammation and modulates antioxidant enzymes in colonic epithelial cells
Published in The Korean journal of internal medicine (01-03-2020)“…Estrogen is known to have protective effect in colorectal cancer development. The aims of this study are to investigate whether estradiol treatment reduces…”
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20
Açaí Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice
Published in Gut and liver (01-03-2017)“…The aim of this study was to investigate the protective effect of açaí against azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer…”
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