Search Results - "LECAILLON, J. B"

Pharmacokinetics and tolerability of formoterol in healthy volunteers after a single high dose of Foradil dry powder Inhalation via aerolizer by LECAILLON, J. B, KAISER, G, PALMISANO, M, MORGAN, J, DELLA CIOPPA, G

“…The pharmacokinetics of the long-acting beta2-agonist formoterol fumarate, which is a racemate of the (S,S)- and (R,R)-enantiomers were evaluated in 12 healthy…”
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Effect of food on the bioavailability of triclabendazole in patients with fascioliasis by Lecaillon, J. B., Godbillon, J., Campestrini, J., Naquira, C., Miranda, L., Pacheco, R., Mull, R., Poltera, A. A.

“…Aims  Preliminary results indicate higher absorption of triclabendazole (TCBZ) administered postprandially. Therefore, the influence of food on the…”
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The influence of food on the disposition of the antiepileptic rufinamide in healthy volunteers by Cardot, J.-M., Lecaillon, J.-B., Czendlik, C., Godbillon, J.

“…The effect of food on the pharmacokinetics of the antiepileptic rufinamide was investigated in healthy volunteers. Twelve subjects were treated with single…”
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The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites by ROUAN, M. C, LECAILLON, J. B, GODBILLON, J, MENARD, F, DARRAGON, T, MEYER, P, KOURILSKY, O, HILLION, D, ALDIGIER, J. C, JUNGERS, P

“…We have studied the effect of renal impairment on the pharmacokinetics of oxcarbazepine, its active monohydroxy-metabolite (which predominates in plasma),…”
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Determination of cefsulodin, cefotiam, cephalexin, cefotaxime, desacetyl-cefotaxime, cefuroxime and cefroxadin in plasma and urine by high-performance liquid chromatography by Lecaillon, J B, Rouan, M C, Souppart, C, Febvre, N, Juge, F

“…Closely related methods for the determination of several cephalosporins in plasma and urine are described. Deproteinized plasma or diluted urine is directly…”
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Comparative evaluation of cardioselectivity of metoprolol OROS and atenolol: a double-blind, placebo-controlled crossover study by Tantucci, C, Bruni, B, Dottorini, M L, Peccini, F, Motolese, M, Lecaillon, J B, Sorbini, C A, Grassi, V

“…Cardioselectivity of a single oral dose of metoprolol oral osmotic (OROS) (14/190 mg) and atenolol (100 mg) was compared in 12 patients with reversible…”
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Bioequivalence assessment: a pharmaceutical industry perspective by Godbillon, J, Cardot, J M, Lecaillon, J B, Lefevre, G, Sioufi, A

“…Various aspects of bioequivalence are investigated in this paper. Some aspects dealing with bioequivalence studies conducted either during the development of…”
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Pharmacokinetics of cadralazine in a large group of hypertensive patients chronically treated with cadralazine: advantage over a conventional study in a small group of patients by Lecaillon, J B, Dubois, J P, Darragon, T, Motolese, M, Racine, A, Ducret, F, Grouberman, D, Cordonnier, D, Chanard, J, Glorioso, M

“…The concentrations of cadralazine in plasma were studied in 101 hypertensive patients treated with oral doses of 10, 15, or 20 mg of cadralazine once daily…”
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Pharmacokinetics of cefotiam in humans by ROUAN, M.-C, LECAILLON, J.-B, GUIBERT, J, MODAI, J, SCHOELLER, J.-P

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Pharmacokinetics of cefotiam and cefsulodin after simultaneous administration to patients with impaired renal function by LECAILLON, J. B, ROUAN, M. C, BINSWANGER, U, GUIBERT, J, SCHOELLER, J. P

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The influence of food on the pharmacokinetics of CGP 6140 (amocarzine) after oral administration of a 1200 mg single dose to patients with onchocerciasis by Lecaillon, JB, Dubois, JP, Soula, G, Pichard, E, Poltera, AA, Ginger, CD

“…Eleven male patients from Mali with Onchocerca volvulus infections received in random order a 1200 mg single oral dose of CGP 6140 after an overnight fast and…”
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Pharmacokinetics of oxiracetam in elderly patients after 800 mg oral doses, comparison with non-geriatric healthy subjects by LECAILLON, J. B, DUBOIS, J. P, COPPENS, H, DARRAGON, T, THEOBALD, W, REUMOND, G, BECK, H

“…The pharmacokinetics of oxiracetam have been studied in eighteen elderly patients and in six healthy non-geriatric adults. A 800 mg single oral dose was…”
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Determination of metoprolol and its alpha-hydroxylated metabolite in human plasma by high-performance liquid chromatography by Lecaillon, J B, Godbillon, J, Abadie, F, Gosset, G

“…A high-performance liquid chromatographic method has been developed for the simultaneous determination of metoprolol and its alpha-hydroxylated metabolite in…”
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Automated and sensitive method for the determination of formoterol in human plasma by high-performance liquid chromatography and electrochemical detection by Campestrini, J, Lecaillon, J.B, Godbillon, J

“…An automated high-performance liquid chromatography (HPLC) method for the determination of formoterol in human plasma with improved sensitivity has been…”
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Fully automated analytical system using liquid-solid extraction and liquid chromatography for the determination of CGP 6140 in plasma by Rouan, M C, Campestrini, J, Lecaillon, J B, Dubois, J P, Lamontagne, M, Pichon, B

“…Liquid-solid extraction on disposable extraction columns (DECs) and liquid chromatography can be combined in a completely automated analyser. The Gilson ASPEC…”
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Pharmacokinetics of CGP 6140 (amocarzine) after oral administration of single 100‐1600 mg doses to patients with onchocerciasis by Lecaillon, JB, Dubois, JP, Awadzi, K, Poltera, AA, Ginger, CD

“…The concentrations of CGP 6140 [4‐nitro‐4′‐(N‐methyl‐ piperazinylthiocarbonylamido)‐diphenylamine] and of its N‐oxide metabolite, CGP 13,231, were measured in…”
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Pharmacokinetic comparison of cefroxadin (CGP 9000) and cephalexin by simultaneous administration to humans by Lecaillon, J B, Hirtz, J L, Schoeller, J P, Humbert, G, Vischer, W

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Influence of food on the absorption of metoprolol administered as an Oros drug delivery system to man by Lecaillon, JB, Massias, P, Schoeller, JP, Abadie, F

“…The influence of food on the release, absorption and metabolism of metoprolol has been studied after single administration of a 19/190 Oros system to eight…”
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Automated microanalysis of oxcarbazepine and its monohydroxy and transdiol metabolites in plasma by liquid chromatography by Rouan, M C, Decherf, M, Le Clanche, V, Lecaillon, J B, Godbillon, J

“…An automated high-performance liquid chromatographic method for the simultaneous determination of oxcarbazepine and its monohydroxy and transdiol metabolites…”
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Pharmacokinetics of cadralazine and its hydrazino-metabolite in patients with renal impairment after repeated administration of 5 mg once daily by Marichal, J F, Brunel, P, Lecaillon, J B, Godbillon, J, Faller, B, Brignon, P, Ménard, J

“…Since the hydrazino-pyridazine metabolite of cadralazine, CGP 22 639 is believed to contribute to the activity of the drug, its pharmacokinetics and that of…”
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