Search Results - "LECA, G"

p38 MAPK and MSK1 mediate caspase-8 activation in manganese-induced mitochondria-dependent cell death by El Mchichi, B, Hadji, A, Vazquez, A, Leca, G

“…Heavy metals are important regulators of cell apoptosis. Manganese (Mn(2+)) is a potent inducer of apoptosis in different cell types, but the precise…”
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p38-mediated Regulation of an Fas-associated Death Domain Protein-independent Pathway Leading to Caspase-8 Activation during TGFβ-induced Apoptosis in Human Burkitt Lymphoma B Cells BL41 by Schrantz, Nicolas, Bourgeade, Marie-Françoise, Mouhamad, Shahul, Leca, Gérald, Sharma, Surendra, Vazquez, Aimé

“…On binding to its receptor, transforming growth factor β (TGFβ) induces apoptosis in a variety of cells, including human B lymphocytes. We have previously…”
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Zinc-mediated regulation of caspases activity: dose-dependent inhibition or activation of caspase-3 in the human Burkitt lymphoma B cells (Ramos) by Schrantz, N, Auffredou, M T, Bourgeade, M F, Besnault, L, Leca, G, Vazquez, A

“…Divalent cations, including Zinc and Manganese ions, are important modulators of cell activation. We investigated the ability of these two divalent cations to…”
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TGFβ-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL by Clybouw, C, E L Mchichi, B, Hadji, A, Portier, A, Auffredou, M T, Arnoult, D, Leca, G, Vazquez, A

“…In this study, we showed that the transforming growth factor β (TGFβ)-mediated apoptosis of Burkitt's lymphoma BL41 cells is dependent on the BH3-only protein…”
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B Cell Receptor Cross-Linking Triggers a Caspase-8- Dependent Apoptotic Pathway That Is Independent of the Death Effector Domain of Fas-Associated Death Domain Protein by Besnault, Laurence, Schrantz, Nicolas, Auffredou, Marie Therese, Leca, Gerald, Bourgeade, Marie Francoise, Vazquez, Aime

“…We have previously reported that B cell receptors, depending on the degree to which they are cross-linked, can promote apoptosis in various human B cell types…”
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Inhibition of superoxide production in B lymphocytes by rac antisense oligonucleotides by DORSEUIL, O, VAZQUEZ, A, LANG, P, BERTOGLIO, J, GACON, G, LECA, G

“…Rac1 and Rac2 gene products are small GTP-binding proteins showing 92% homology to each other. According to recent studies performed in cell-free systems, Rac1…”
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Significant Enlargement of a Specific Subset of CD3+CD8+Peripheral Blood Leukocytes Mediating Cytotoxic T-Lymphocyte Activity During Human Immunodeficiency Virus Infection by Bensussan, A., Rabian, C., Schiavon, V., Bengoufa, D., Leca, G., Boumsell, L.

“…We have obtained a monoclonal antibody termed BY55 that defines an 80-kDa cell-surface structure on a subset of circulating peripheral blood mononucleocytes…”
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Mechanism of maturation and nature of carbohydrate chains of boar sperm acrosin by Moos, J., Tesarik, J., Leca, G., Peknicova, J.

“…The acrosin zymogen proacrosin exists in two molecular forms which are believed to be single-chain polypeptides. During autoactivation in a cell-free system,…”
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Reversible inhibition of fertility in mice by passive immunization with anticumulus oophorus antibodies by TESARIK, J, TESTART, J, LECA, G, NOME, F

“…The mucified cumulus oophorus represents an outer enveloping layer around ovulated mammalian oocytes. This coat in its definitive expanded form appears late in…”
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Predominant expression of circulating CD3+lymphocytes bearing gamma T cell receptor in a prolonged immunodeficiency after allogeneic bone marrow transplantation by VILMER, E, GUGLIELMI, P, DAVID, V, LECA, G, RABIAN, C, DEGOS, L, BOIRON, M, BENSUSSAN, A

“…The cell surface expression of alpha:beta heterodimer was studied using WT31 monoclonal antibody, in peripheral blood lymphocytes (PBL) from a patient who…”
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Prominent expansion of circulating lymphocytes bearing gamma T-cell receptors, with preferential expression of variable gamma genes after allogeneic bone marrow transplantation by Vilmer, E, Triebel, F, David, V, Rabian, C, Schumpp, M, Leca, G, Degos, L, Hercend, T, Sigaux, F, Bensussan, A

“…The presence of two distinct T-cell receptors (TCR) alpha/beta dimers or gamma/delta dimers, was systematically analyzed in peripheral blood lymphocytes form…”
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T-cell chemiluminescence. A novel aspect of T-cell membrane activation studied with a Jurkat tumour cell line by Benichou, G, Kanellopoulos, J M, Mitenne, F, Galanaud, P, Leca, G

“…The binding of mitogenic lectins phytohaemagglutinin (PHA), concanavalin A (Con A) and/or of monoclonal antibodies to different receptors such as antigen…”
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The sheep erythrocyte receptor and both alpha and beta chains of the human T-lymphocyte antigen receptor bind the mitogenic lectin (phytohaemagglutinin) from Phaseolus vulgaris by Leca, G, Boumsell, L, Fabbi, M, Reinherz, E L, Kanellopoulos, J M

“…We have studied the interaction of mitogenic lectins such as phytohaemagglutinin (PHA) and concanavalin A (Con A) with both surface molecules which, by the use…”
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EBV Infection of Human B Lymphocytes Leads to Down-Regulation of Bim Expression: Relationship to Resistance to Apoptosis by Clybouw, Cyril, Mchichi, Bouchra, Mouhamad, Shahul, Auffredou, Marie Therese, Bourgeade, Marie Francoise, Sharma, Surendra, Leca, Gerald, Vazquez, Aime

“…EBV infects a large proportion of the human population worldwide and is one of the major viruses with human B lymphocyte tropism. It can immortalize human B…”
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IL-4 counteracts anti-mu-induced human B cell proliferation: involvement of a cAMP-dependent inhibitory pathway by Taieb, J, Leca, G, Auffredou, M T, Galanaud, P, Vazquez, A

“…In this report we show that IL-4 inhibits DNA synthesis induced by stimulation of human B cells with mitogenic doses of either soluble anti-mu mAb DA44 or…”
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Biochemical purification of various receptor molecules involved in human T lymphocyte activation. Separation of 9.3 antigen from the T cell receptor for antigen by Leca, G, Benichou, G, Bensussan, A, Kanellopoulos, J

“…The now classical major histocompatibility complex (MHC)-restricted receptor for antigen on human T lymphocytes has been identified as a 90 kDa…”
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The human cell surface glycoprotein complex (gp 120,200) recognized by monoclonal antibody K20 is a component binding to phytohaemagglutinin on T cells by Amiot, M, Bernard, A, Tran, H C, Leca, G, Kanellopoulos, J M, Boumsell, L

“…Monoclonal antibody K20 recognizes a human glycoprotein complex that is not restricted to haematopoietic lineages but is preferentially expressed on early…”
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TGFb-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL by Clybouw, C, E L Mchichi, B, Hadji, A, Portier, A, Auffredou, M T, Arnoult, D, Leca, G, Vazquez, A

“…In this study, we showed that the transforming growth factor b (TGFb)-mediated apoptosis of Burkitt's lymphoma BL41 cells is dependent on the BH3-only protein…”
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BimL upregulation induced by BCR cross-linking in BL41 Burkitt’s lymphoma results from a splicing mechanism of the BimEL mRNA by Clybouw, Cyril, Hadji, Abbas, ElMchichi, Bouchra, Auffredou, Marie-Thérèse, Leca, Gérald, Vazquez, Aimé

“…B lymphocyte receptor-mediated apoptosis is associated with increased expression of the BimL isoform of Bim. The mechanisms involved in the regulation of BimL…”
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Expression of the T cell gamma gene by a functionally defined human T cell clone. Characterization at DNA, RNA, and cell membrane level by David, V, Leca, G, Vilmer, E, Guglielmi, P, Chouaib, S, Kanellopoulos, J, Sigaux, F, Bensussan, A

“…In the present study we describe one CD2+CD3+ clone termed DS6 which expressed neither CD4 nor CD8 differentiation antigens and failed to react with WT31, a…”
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