Search Results - "LEAF, A"

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome by Miao, Edward A, Mao, Dat P, Yudkovsky, Natalya, Bonneau, Richard, Lorang, Cynthia G, Warren, Sarah E, Leaf, Irina A, Aderem, Alan

“…The mammalian innate immune system uses Toll-like receptors (TLRs) and Nod-LRRs (NLRs) to detect microbial components during infection. Often these molecules…”
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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria by Mao, Dat P, Wewers, Mark D, Miao, Edward A, Warren, Sarah E, Treuting, Piper M, Leaf, Irina A, Dors, Monica, Sarkar, Anasuya, Aderem, Alan

“…Pyroptosis is a form of proinflammatory cell suicide whose physiological importance is unclear. Aderem and colleagues show that pyroptosis can be integral to…”
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Preterm birth and body composition at term equivalent age: a systematic review and meta-analysis by Johnson, Mark J, Wootton, Stephen A, Leaf, Alison A, Jackson, Alan A

“…Infants born preterm are significantly lighter and shorter on reaching term equivalent age (TEA) than are those born at term, but the relation with body…”
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Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter by Kraus, Richard J, Yu, Xianming, Cordes, Blue-Leaf A, Sathiamoorthi, Saraniya, Iempridee, Tawin, Nawandar, Dhananjay M, Ma, Shidong, Romero-Masters, James C, McChesney, Kyle G, Lin, Zhen, Makielski, Kathleen R, Lee, Denis L, Lambert, Paul F, Johannsen, Eric C, Kenney, Shannon C, Mertz, Janet E

“…When confronted with poor oxygenation, cells adapt by activating survival signaling pathways, including the oxygen-sensitive transcriptional regulators called…”
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Introducing enteral feeds in the high-risk preterm infant by Leaf, A

“…Summary Establishing enteral feeding in high-risk, very preterm infants is difficult: they are born at a time of rapid growth and development, yet immaturity…”
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Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury by Leaf, Irina A, Nakagawa, Shunsaku, Johnson, Bryce G, Cha, Jin Joo, Mittelsteadt, Kristen, Guckian, Kevin M, Gomez, Ivan G, Altemeier, William A, Duffield, Jeremy S

“…Fibrotic disease is associated with matrix deposition that results in the loss of organ function. Pericytes, the precursors of myofibroblasts, are a source of…”
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Reactivation of Epstein-Barr Virus by HIF-1α Requires p53 by Kraus, Richard J, Cordes, Blue-Leaf A, Sathiamoorthi, Saraniya, Patel, Parita, Yuan, Xueying, Iempridee, Tawin, Yu, Xianming, Lee, Denis L, Lambert, Paul F, Mertz, Janet E

“…We previously reported that the cellular transcription factor hypoxia-inducible factor 1α (HIF-1α) binds a hypoxia response element (HRE) located within the…”
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Early parenteral nutrition and growth outcomes in preterm infants: a systematic review and meta-analysis by Moyses, Helen E, Johnson, Mark J, Leaf, Alison A, Cornelius, Victoria R

“…Background: The achievement of adequate nutritional intakes in preterm infants is challenging and may explain the poor growth often seen in this group. The use…”
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HIV Infection, Cardiovascular Disease Risk Factor Profile, and Risk for Acute Myocardial Infarction by Paisible, Anne-Lise, Chang, Chung-Chou H, So-Armah, Kaku A, Butt, Adeel A, Leaf, David A, Budoff, Matthew, Rimland, David, Bedimo, Roger, Goetz, Matthew B, Rodriguez-Barradas, Maria C, Crane, Heidi M, Gibert, Cynthia L, Brown, Sheldon T, Tindle, Hilary A, Warner, Alberta L, Alcorn, Charles, Skanderson, Melissa, Justice, Amy C, Freiberg, Matthew S

“…BACKGROUND:Traditional cardiovascular disease risk factors (CVDRFs) increase the risk of acute myocardial infarction (AMI) among HIV-infected (HIV+)…”
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Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium by Aachoui, Youssef, Kajiwara, Yuji, Leaf, Irina A., Mao, Dat, Ting, Jenny P.-Y., Coers, Jörn, Aderem, Alan, Buxbaum, Joseph D., Miao, Edward A.

“…The inflammatory caspases 1 and 11 are activated in response to different agonists and act independently to induce pyroptosis. In the context of IL-1β/IL-18…”
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Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney by Puranik, Amrutesh S., Leaf, Irina A., Jensen, Mark A., Hedayat, Ahmad F., Saad, Ahmad, Kim, Ki-Wook, Saadalla, Abdulrahman M., Woollard, John R., Kashyap, Sonu, Textor, Stephen C., Grande, Joseph P., Lerman, Amir, Simari, Robert D., Randolph, Gwendalyn J., Duffield, Jeremy S., Lerman, Lilach O.

“…Renal artery stenosis (RAS) caused by narrowing of arteries is characterized by microvascular damage. Macrophages are implicated in repair and injury, but the…”
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HIV Status, Burden of Comorbid Disease, and Biomarkers of Inflammation, Altered Coagulation, and Monocyte Activation by Armah, Kaku A., McGinnis, Kathleen, Baker, Jason, Gibert, Cynthia, Butt, Adeel A., Bryant, Kendall J., Goetz, Matthew, Tracy, Russell, Oursler, Krisann K., Rimland, David, Crothers, Kristina, Rodriguez-Barradas, Maria, Crystal, Steve, Gordon, Adam, Kraemer, Kevin, Brown, Sheldon, Gerschenson, Mariana, Leaf, David A., Deeks, Steven G., Rinaldo, Charles, Kuller, Lewis H., Justice, Amy, Freiberg, Matthew

“…Background. Biomarkers of inflammation, altered coagulation, and monocyte activation are associated with mortality and cardiovascular disease (CVD) in the…”
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Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2 by Warren, Sarah E, Armstrong, Abraham, Hamilton, M Kristina, Mao, Dat P, Leaf, Irina A, Miao, Edward A, Aderem, Alan

“…Pathogens are detected by pattern recognition receptors that, upon activation, orchestrate an appropriate immune response. The TLRs and the nucleotide-binding…”
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Drugs That Mimic Hypoxia Selectively Target EBV-Positive Gastric Cancer Cells by Cordes, Blue-Leaf A, Bilger, Andrea, Kraus, Richard J, Ward-Shaw, Ella T, Labott, Madeline R, Lee, Shinhyo, Lambert, Paul F, Mertz, Janet E

“…Latent infection of Epstein-Barr virus (EBV) is associated with lymphoid and epithelial cell cancers, including 10% of gastric carcinomas. We previously…”
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Academic Detailing as a Health Information Technology Implementation Method: Supporting the Design and Implementation of an Emergency Department-Based Clinical Decision Support Tool to Prevent Future Falls by Barton, Hanna J, Maru, Apoorva, Leaf, Margaret A, Hekman, Daniel J, Wiegmann, Douglas A, Shah, Manish N, Patterson, Brian W

“…Clinical decision support (CDS) tools that incorporate machine learning-derived content have the potential to transform clinical care by augmenting clinicians'…”
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Feeding growth restricted preterm infants with abnormal antenatal Doppler results by Dorling, J, Kempley, S, Leaf, A

“…Absence or reversal of end diastolic flow (AREDF) in the umbilical artery is associated with poor outcome, and elective premature delivery is common. Feeding…”
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Driving experience, crashes and traffic citations of teenage beginning drivers by McCartt, Anne T, Shabanova, Veronika I, Leaf, William A

“…Teenagers were surveyed by telephone every 6 months from their freshman to senior high school years ( N=911). Self-reported crash involvements and citations…”
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Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain by Margosio, Barbara, Rusnati, Marco, Bonezzi, Katiuscia, Cordes, Blue-leaf A., Annis, Douglas S., Urbinati, Chiara, Giavazzi, Raffaella, Presta, Marco, Ribatti, Domenico, Mosher, Deane F., Taraboletti, Giulia

“…Thrombospondin-1, an antiangiogenic matricellular protein, binds with high affinity to the angiogenic fibroblast growth factor-2, affecting its bioavailability…”
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A model of seam pucker and its applications Part I: theoretical by Amir, Muhammad, Leaf, Gerry A. V., Stylios, George K.

“…This article considers a simple model of the lock stitch (301) seam, and uses it to derive a measure of the severity of puckering in the seam. The numerical…”
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Vitamins for babies and young children by Leaf, A A

“…The Welfare Food Scheme has recently been reviewed, and, although changes are being made, free vitamin supplements for children <4 years old will remain an…”
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