Search Results - "LE MEUR, Yannick"
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Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease
Published in American journal of human genetics (02-06-2016)“…Autosomal-dominant polycystic kidney disease (ADPKD) is a common, progressive, adult-onset disease that is an important cause of end-stage renal disease…”
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Genetics and Pathogenesis of Autosomal Dominant Polycystic Kidney Disease: 20 Years On
Published in Human mutation (01-12-2014)“…ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD), the most common inherited kidney disorder, is characterized by the progressive development and…”
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Consensus Report on Therapeutic Drug Monitoring of Mycophenolic Acid in Solid Organ Transplantation
Published in Clinical journal of the American Society of Nephrology (01-02-2010)“…With the increasing use of mycophenolic acid (MPA) in solid organ transplantation, the need for more accurate drug dosing has become evident. Personalized…”
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Opportunities to Optimize Tacrolimus Therapy in Solid Organ Transplantation : Report of the European Consensus Conference
Published in Therapeutic drug monitoring (01-04-2009)“…In 2007, a consortium of European experts on tacrolimus (TAC) met to discuss the most recent advances in the drug/dose optimization of TAC taking into account…”
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Selection of Pneumocystis jirovecii Inosine 5′-Monophosphate Dehydrogenase Mutants in Solid Organ Transplant Recipients: Implication of Mycophenolic Acid
Published in Journal of fungi (Basel) (01-10-2021)“…Mycophenolic acid (MPA) targets the inosine 5′-monophosphate dehydrogenase (IMPDH) of human lymphocytes. It is widely used as an immunosuppressant to prevent…”
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Maximum a posteriori bayesian estimation of mycophenolic acid pharmacokinetics in renal transplant recipients at different postgrafting periods
Published in Therapeutic drug monitoring (01-06-2005)“…The aim of this study was to develop maximum a posteriori probability (MAP) Bayesian estimators of mycophenolic acid (MPA) pharmacokinetics (PK) capable of…”
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Mutations in GANAB, Encoding the Glucosidase IIa Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease
Published in American journal of human genetics (02-06-2016)“…Autosomal-dominant polycystic kidney disease (ADPKD) is a common, progressive, adult-onset disease that is an important cause of end-stage renal disease…”
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Comparison of liquid chromatography-tandem mass spectrometry with a commercial enzyme-multiplied immunoassay for the determination of plasma MPA in renal transplant recipients and consequences for therapeutic drug monitoring
Published in Therapeutic drug monitoring (01-12-2004)“…Mycophenolic acid (MPA) is an immunosuppressive drug partly metabolized to MPA-glucuronide (MPAG), which is pharmacologically inactive. The currently available…”
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Type of PKD1 Mutation Influences Renal Outcome in ADPKD
Published in Journal of the American Society of Nephrology (01-06-2013)“…Autosomal dominant polycystic kidney disease (ADPKD) is heterogeneous with regard to genic and allelic heterogeneity, as well as phenotypic variability. The…”
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Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice
Published in Nephrology, dialysis, transplantation (01-03-2016)“…Recently, the European Medicines Agency approved the use of the vasopressin V2 receptor antagonist tolvaptan to slow the progression of cyst development and…”
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First‐in‐human use of a marine oxygen carrier (M101) for organ preservation: A safety and proof‐of‐principle study
Published in American journal of transplantation (01-06-2020)“…The medical device M101 is an extracellular hemoglobin featuring high oxygen‐carrying capabilities. Preclinical studies demonstrated its safety as an additive…”
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REPRISE: tolvaptan in advanced polycystic kidney disease
Published in Kidney international (01-02-2018)Get more information
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HEMO2life® improves renal function independent of cold ischemia time in kidney recipients: A comparison with a large multicenter prospective cohort study
Published in Artificial organs (01-04-2022)“…Background M101 is an extracellular hemoglobin isolated from a marine lugworm and is present in the medical device HEMO2life®. The clinical investigation OXYOP…”
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Incidence of cytomegalovirus infection in seropositive kidney transplant recipients treated with everolimus: A randomized, open‐label, multicenter phase 4 trial
Published in American journal of transplantation (01-05-2022)“…Cytomegalovirus (CMV) persists as the most frequent opportunistic infection among solid organ transplant recipients. This multicenter trial aimed to test…”
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Adaptative Strategy of Immunosuppressive Drugs Dosage Adjustments When Combined With Nirmatrelvir/Ritonavir in Solid Organ Transplant Recipients With COVID-19
Published in Transplant international (26-03-2024)“…Nirmatrelvir/ritonavir is a promising option for preventing severe COVID-19 in solid organ transplant recipients with SARS-CoV-2 infection. However, concerns…”
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Among CMV‐positive renal transplant patients receiving non‐T‐cell depleting induction, the absence of CMV disease prevention is a safe strategy: A retrospective cohort of 372 patients
Published in Transplant infectious disease (01-06-2021)“…Cytomegalovirus (CMV) is the most common opportunistic pathogen affecting renal transplant recipients, especially in the first months. CMV‐seropositive renal…”
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Impact of Switching From Immediate- or Prolonged-Release to Once-Daily Extended-Release Tacrolimus (LCPT) on Tremor in Stable Kidney Transplant Recipients: The Observational ELIT Study
Published in Transplant international (17-04-2024)“…Once-daily extended-release tacrolimus (LCPT) exhibits increased bioavailability versus immediate-release (IR-TAC) and prolonged release (PR-TAC) tacrolimus…”
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Correction of Postkidney Transplant Anemia Reduces Progression of Allograft Nephropathy
Published in Journal of the American Society of Nephrology (01-02-2012)“…Retrospective studies suggest that chronic allograft nephropathy might progress more rapidly in patients with post-transplant anemia, but whether correction of…”
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Vitamin K antagonist has a higher impact than heparin in preventing circuit clotting in chronic haemodialysis patients
Published in Clinical kidney journal (01-08-2020)“…In dialysis sessions, some data suggest that decreasing or even avoiding additional anticoagulation by heparin is possible among patients already treated with…”
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Adult-Onset Eculizumab-Resistant Hemolytic Uremic Syndrome Associated With Cobalamin C Deficiency
Published in American journal of kidney diseases (01-01-2014)“…A 20-year-old man was hospitalized for malignant hypertension, mechanical hemolysis, and kidney failure. Kidney biopsy confirmed glomerular and arteriolar…”
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