Search Results - "LE LIBOUX, A"

Intra-articular absorption and distribution of ketoprofen after topical plaster application and oral intake in 100 patients undergoing knee arthroscopy by ROLF, C, ENGSTRÖM, B, BEAUCHARD, C, JACOBS, L. D, LE LIBOUX, A

“…The primary objective of this study was to assess the kinetics of ketoprofen in synovial fluid and intra-articular tissues in relation to plasma. The secondary…”
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An open, randomized study of ketoprofen in patients in surgery for Achilles or patellar tendinopathy by Rolf, C, Movin, T, Engstrom, B, Jacobs, L D, Beauchard, C, Le Liboux, A

“…To assess the concentration of ketoprofen, after topical plaster application, in various tissues in relation to plasma levels in 60 patients undergoing surgery…”
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A comparative pharmacokinetic and pharmacodynamic study of conventional and sustained-release preparations of acebutolol in healthy volunteers by Fleurot, O, Lecocq, B, Lecocq, V, Le Liboux, A, Montay, G, Frydman, A, Jaillon, P

“…Pharmacokinetics and the degree of beta-blockade of sustained release (SR) acebutolol (500 mg/day) and conventional acebutolol (200 mg tid) were examined after…”
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A phase I, double-blind, placebo-controlled study of the tolerance and pharmacokinetic behaviour of RP 59500 by Etienne, S D, Montay, G, Le Liboux, A, Frydman, A, Garaud, J J

“…The tolerance and pharmacokinetic behaviour of a new injectable streptogramin antibiotic, RP 59500 were evaluated on 26 healthy male volunteers in a…”
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Kinetics of spiramycin/metronidazole (Rodogyl) in human gingival crevicular fluid, saliva and blood by Rotzetter, P A, Le Liboux, A, Pichard, E, Cimasoni, G

“…The peripheral distribution of spiramycin and metronidazole, which are combined in the proprietary drug "Rodogyl", has been studied in gingival fluid, saliva…”
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Effect of diet on the single- and multiple-dose pharmacokinetics of sustained-release ketoprofen by DE LIBOUX, A, TEULE, M, FRYDMAN, A, OOSTERHUIS, B, JONKMAN, J. H. G

“…The indirect effect of diet on the single- and multiple-dose pharmacokinetics of sustained-release ketoprofen was studied in 16 healthy male volunteers. In an…”
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The pharmacokinetics and pharmacodynamics of enoxaparin in obese volunteers by Sanderink, Ger‐Jan, Le Liboux, Aimé, Jariwala, Navin, Harding, Neasa, Ozoux, Marie‐Laure, Shukla, Umesh, Montay, Guy, Boutouyrie, Bruno, Miro, Adelaida

“…Objectives The objective of this study was to compare the pharmacokinetics of the low‐molecular‐weight heparin enoxaparin in obese and nonobese volunteers, by…”
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Secnidazole concentrations in plasma and crevicular fluid after a single oral dose by Tenenbaum, H, Cuisinier, F J, Le Liboux, A, Pichard, E, Montay, G, Frydman, A

“…Metronidazole and related nitroimidazole derivatives, including ornidazole and tinidazole, have been used successfully in the treatment of periodontal…”
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Comparative bioavailability study of cefixime administered as tablets or aqueous solution by Montay, G, Masala, F, Le Roux, Y, Le Liboux, A, Uhlrich, J, Chassard, D, Thebault, J J, Roche, G, Frydman, A

“…The relative bioavailability of cefixime was studied in 24 healthy male volunteers, with each subject receiving a single 400mg dose of cefixime administered as…”
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Steady state pharmacokinetics of zopiclone during multiple oral dosing (7.5 mg nocte) in patients with severe chronic renal failure by Viron, B, De Meyer, M, Le Liboux, A, Frydman, A, Maillard, F, Mignon, F, Gaillot, J

“…Zopiclone is a new hypnotic cyclopyrrolone with a short elimination half-life (5.3 h). The pharmacokinetic profile of this drug was studied in 7 chronic renal…”
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Simultaneous high-performance liquid chromatographic determination of quinupristin, dalfopristin and their main metabolites in human plasma by Le Liboux, A., Pasquier, O., Montay, G.

“…Quinupristin–dalfopristin (30:70, w/w) is a new streptogramin, which has been developed for intravenous use. A specific and sensitive HPLC method was developed…”
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Pharmacokinetics in man of acebutolol and hydrochlorothiazide as single agents and in combination by Roux, A, Le Liboux, A, Delhotal, B, Gaillot, J, Flouvat, B

“…The pharmacokinetics of acebutolol and hydrochlorothiazide (HCT) alone or in combination were studied in 12 healthy subjects in a cross over study. Acebutolol…”
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Pharmacokinetics of Ketoprofen Syrup in Small Children by Kokki, Hannu, Liboux, Aimé Le, Jekunen, Antti, Montay, Guy, Heikkinen, Marja

“…Ketoprofen is a nonsteroidal anti‐inflammatory drug with analgesic, anti‐inflammatory, and antipyretic properties. Its pharmacokinetics has not been determined…”
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A Comparison of the Pharmacokinetics and Tolerability of Riluzole after Repeat Dose Administration in Healthy Elderly and Young Volunteers by Liboux, Aimé Le, Cachia, Jean-Paul, Kirkesseli, Stéphane, Gautier, Jean-Yves, Guimart, Colette, Montay, Guy, Peeters, Pierre A. M., Groen, Edwin, Jonkman, Jan H. G., Wemer, Johannes

“…The pharmacokinetics and tolerability of the novel antiexcitatory agent, riluzole, were compared in 18 healthy elderly and 18 healthy gender‐ and…”
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Pharmacokinetics of nicorandil by Frydman, Armand M., Chapelle, Philip, Diekmann, Herbert, Bruno, René, Thebault, Jean J., Bouthier, Jean, Caplain, Henri, Ungethuem, Wolfgang, Gaillard, Claude, Le Liboux, Aimé, Renard, Alain, Gaillot, Jean

“…This report presents the findings of some studies on single intravenous and oral dosing performed in healthy volunteers to determine the pharmacokinetics and…”
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Pharmacokinetics of cefixime in healthy volunteers after a single oral administration of 200 mg by Montay, G, Le Liboux, A, Thebault, J J, Roche, G, Frydman, A, Gaillot, J

“…The antibacterial activity of cefixime is identical with that of parenteral third generation cephalosporins. Its kinetics were studied in 24 healthy male…”
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Pharmacokinetics of pyrimethamine in healthy young volunteers using a new solid phase extraction/HPLC method by Le Liboux, A, Duquesne, H, Montay, G, Chassard, D, Pichard, E, Thebault, J J, Frydman, A, Gaillot, J

“…The single dose pharmacokinetics of pyrimethamine were determined in 12 healthy young volunteers using a newly developed fully automated analytical system…”
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Population pharmacokinetics of riluzole in patients with amyotrophic lateral sclerosis by Bruno, René, Vivier, Nicole, Montay, Guy, Liboux, Aim éLe, Powe, Larry K., Delumeau, Jean‐Christophe, Rhodes, Gerald R.

“…Objectives To characterize the population pharmacokinetic of riluzole in patients with amyotrophic lateral sclerosis (ALS). Methods One hundred patients with…”
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Single- and Multiple-Dose Pharmacokinetics of Riluzole in White Subjects by Liboux, Aimé Le, Lefebvre, Patricia, Roux, Yvonne Le, Truffinet, Philippe, Aubeneau, Michel, Kirkesseli, Stéphane, Montay, Guy

“…Riluzole is a novel neuroprotective agent that has been developed for the treatment of amyotrophic lateral sclerosis. A series of studies was undertaken to…”
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Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography by Le Liboux, A, Frydman, A, Gaillot, J

“…A high-performance liquid chromatographic method has been developed for the simultaneous determination of zopiclone and its main metabolites (N-oxide and…”
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