Search Results - "LE, Sandra"
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Clinical Evidence and Safety Profile of Emicizumab for the Management of Children with Hemophilia A
Published in Drug design, development and therapy (01-02-2020)“…Emicizumab is a bispecific, humanized, monoclonal antibody mimicking the factor (F) VIII cofactor activity in mediating the generation of FXa by FIXa in…”
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Comparison of current platelet functional tests for the assessment of aspirin and clopidogrel response. A review of the literature
Published in Thrombosis and haemostasis (01-10-2016)“…The two most widely used antiplatelet drugs in the world are aspirin and clopidogrel. However, some patients on aspirin and/or clopidogrel therapy do not…”
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Heat-affected zone ferrite content control of a duplex stainless steel grade to enhance weldability
Published in Welding in the world (01-08-2022)“…Duplex stainless steels (DSS) have a microstructure consisting of 50% ferrite α and 50% austenite γ. This two-phase microstructure provides the duplex…”
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Gene therapy for haemophilia A and B, from basic principles to clinical implementation: An illustrated review
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2024)“…Introduction With recent approval of the first two gene therapies for haemophilia A and B, educational materials about AAV‐based gene therapy are needed by the…”
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The Giant Radio Array for Neutrino Detection (GRAND): Science and design
Published in Science China. Physics, mechanics & astronomy (01-01-2020)“…The Giant Radio Array for Neutrino Detection (GRAND) is a planned large-scale observatory of ultra-high-energy (UHE) cosmic particles, with energies exceeding…”
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A 360-degree perspective on adeno-associated virus (AAV)-based gene therapy for haemophilia: Insights from the physician, the nurse and the patient
Published in Orphanet journal of rare diseases (13-05-2024)“…Adeno-associated virus (AAV)-based gene therapy for haemophilia has advanced substantially in the last 13 years; recently, three products have received…”
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Report of surgeries, their outcome and the thrombin generation assay in patients with Factor XI deficiency: A retrospective single‐centre study
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2022)“…Background In patients with FXI deficiency, the risk of surgery‐related bleeding is poorly correlated with plasma FXI activity (FXI:C); the latter can…”
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Immune tolerance induction in the era of emicizumab – still the first choice for patients with haemophilia A and inhibitors?
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2022)“…Introduction The development of inhibitory antibodies is a severe complication of clotting factor replacement therapy in patients with severe haemophilia A…”
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Septic Arthritis Caused by Noncapsulated Haemophilus influenzae
Published in Journal of Clinical Microbiology (01-06-2013)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Thrombotic Complications in Venous Malformations: Are There Differences Between Facial and Other Localizations?
Published in Clinical and applied thrombosis/hemostasis (2020)“…Venous thrombosis (VT) is a frequent complication in venous malformations (VM) in relation with blood stasis and localized intravascular coagulopathy (LIC)…”
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FcRn as a Transporter for Nasal Delivery of Biologics: A Systematic Review
Published in International journal of molecular sciences (17-06-2021)“…FcRn plays a major role in regulating immune homeostasis, but it is also able to transport biologics across cellular barriers. The question of whether FcRn…”
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A single‐centre study of management of pregnant women with von Willebrand disease
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2019)Get full text
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Potential limits of AAV‐based gene therapy with the use of new transgenes expressing factor IX fusion proteins
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2019)“…Introduction The variety of treatment for haemophilia B (HB) has recently improved with the emergence of both AAV‐based gene therapy and bioengineered human…”
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Does learning style influence performance in objective structured clinical examinations?
Published in BMC medical education (03-10-2024)“…Objective Structured Clinical Examinations (OSCEs) aim to assess medical students' clinical skills rather than just their theoretical knowledge. We propose a…”
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The Giant Radio Array for Neutrino Detection
Published in EPJ Web of Conferences (01-01-2017)“…The Giant Radio Array for Neutrino Detection (GRAND) is a planned array of ~ 2·105 radio antennas deployed over ~ 200 000 km2 in a mountainous site. It aims…”
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Resistance of the oyster pathogen Vibrio tasmaniensis LGP32 against grazing by Vannella sp. marine amoeba involves Vsm and CopA virulence factors
Published in Environmental microbiology (01-10-2020)“…Summary Vibrios are ubiquitous in marine environments and opportunistically colonize a broad range of hosts. Strains of Vibrio tasmaniensis present in oyster…”
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Pre-analytical effects of pneumatic tube system transport on routine haematology and coagulation tests, global coagulation assays and platelet function assays
Published in Thrombosis research (01-05-2017)“…Abstract Introduction Pneumatic tube system (PTS) in hospitals is commonly used for the transport of blood samples to clinical laboratories, as it is rapid and…”
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