Search Results - "LAZARIDES, Elias"

An in vivo approach to structure activity relationship analysis of peptide ligands by XIAOMIN FAN, VENEGAS, Ruben, FEY, Robert, VAN DER HEYDE, Henri, BERNARD, Mark A, LAZARIDES, Elias, WOODS, Catherine M

“…The goals in this study were several-fold. First, to optimize the in vivo phage display methodology by incorporating phage pharmacokinetic properties, to…”
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Modulation of Experimental Autoimmune Encephalomyelitis by VLA-2 Blockade by Tsunoda, Ikuo, Terry, Emily Jane, Marble, Benjamin J., Lazarides, Elias, Woods, Catherine, Fujinami, Robert S.

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Adhesion molecules play important roles in cell–cell and…”
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Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway by Woods, C M, Zhu, J, McQueney, P A, Bollag, D, Lazarides, E

“…At therapeutic concentrations, the antineoplastic agent taxol selectively perturbs mitotic spindle microtubules. Taxol has recently been shown to induce…”
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From genes to structural morphogenesis: the genesis and epigenesis of a red blood cell by Lazarides, E

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The synthesis and distribution of desmin and vimentin during myogenesis in vitro by Gard, D L, Lazarides, E

“…Electrophoretic and autoradiographic analyses of the incorporation of 35S--methionine into newly synthesized proteins during myogenesis reveal that presumptive…”
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Actin is the Naturally Occurring Inhibitor of Deoxyribonuclease I by Lazarides, Elias, Lindberg, Uno

“…Various tissues and cells in culture contain a specific inhibitor of DNase I (EC 3.1.4.5). In this paper evidence is presented that this inhibitor is actin,…”
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Actin Antibody: The Specific Visualization of Actin Filaments in Non-Muscle Cells by Lazarides, Elias, Weber, Klaus

“…Actin purified from mouse fibroblasts by sodium dodecyl sulfate gel electrophoresis was used as antigen to obtain an antibody in rabbits. The elicited antibody…”
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Continuous growth of vimentin filaments in mouse fibroblasts by COLEMAN, T. R, LAZARIDES, E

“…We have investigated the dynamics of intermediate filament assembly in vivo by following the fate of heterologous chicken vimentin subunits expressed under the…”
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Erythrocyte and Brain Forms of Spectrin in Cerebellum: Distinct Membrane-Cytoskeletal Domains in Neurons by Lazarides, Elias, Nelson, W. James

“…Chicken cerebellum expresses a polypeptide antigenically and biochemically related to the $\alpha $ subunit of spectrin, an erythrocyte membrane-cytoskeletal…”
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Vimentin downregulation is an inherent feature of murine erythropoiesis and occurs independently of lineage by Sangiorgi, F, Woods, C M, Lazarides, E

“…In mammalian erythropoiesis, the mature cells of the primitive lineage remain nucleated while those of the definitive lineage are anuclear. One of the…”
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Assembly and topogenesis of the spectrin-based membrane skeleton in erythroid development by Lazarides, E, Moon, R T

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Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action by BOLLAG, D. M, MCQUENEY, P. A, JIAN ZHU, HENSENS, O, KOUPAL, L, LIESCH, J, GOETZ, M, LAZARIDES, E, WOODS, C. M

“…Tubulin polymerization into microtubules is a dynamic process, with the equilibrium between growth and shrinkage being essential for many cellular processes…”
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Expression of the Major Neurofilament Subunit in Chicken Erythrocytes by Granger, Bruce L., Lazarides, Elias

“…The 70,000-dalton core polypeptide of neurofilaments, thought to exist only in neurons, has been detected in chicken erythrocytes, where it coexists with…”
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Intermediate filaments as mechanical integrators of cellular space by Lazarides, Elias

“…Five chemically distinct classes of intermediate filaments can be identified within higher eukaryotic cells. Each class is characteristic of a particular cell…”
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The 68,000-Dalton Neurofilament-Associated Polypeptide is a Component of Nonneuronal Cells and of Skeletal Myofibrils by Wang, Chung, Asai, David J., Lazarides, Elias

“…Purified preparations of 10-nm neurofilaments from rat spinal cord and bovine or porcine brain contain a predominant 68,000-dalton polypeptide. This…”
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Phosphorylation of Subunit Proteins of Intermediate Filaments from Chicken Muscle and Nonmuscle Cells by O'Connor, Clare M., Balzer, David R., Lazarides, Elias

“…The phosphorylation of the subunit proteins of intermediate (10-nm) filaments has been investigated in chicken muscle and nonmuscle cells by using a…”
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Fluorescent Localization of Membrane Sites in Glycerinated Chicken Skeletal Muscle Fibers and the Relationship of these Sites to the Protein Composition of the Z Disc by Lazarides, Elias, Granger, Bruce L.

“…Didansyl derivatives of amino acids and N-phenyl-1-naphthylamine were used to localize membrane hydrophobic sites in glycerol-extracted chicken skeletal muscle…”
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Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist by Sircar, Ila, Gudmundsson, Kristjan S, Martin, Richard, Liang, Jimmy, Nomura, Sumihiro, Jayakumar, Honnappa, Teegarden, Bradley R, Nowlin, Dawn M, Cardarelli, Pina M, Mah, Jason R, Connell, Samuel, Griffith, Ronald C, Lazarides, Elias

“…alpha(4)beta(1) and alpha(4)beta(7) integrins are key regulators of physiologic and pathologic responses in inflammation and autoimmune disease. The…”
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Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: Discovery of TR-14035, a dual α4β7/α4β1 integrin antagonist by SIRCAR, Ila, GUDMUNDSSON, Kristjan S, CONNELL, Samuel, GRIFFITH, Ronald C, LAZARIDES, Elias, MARTIN, Richard, LIANG, Jimmy, NOMURA, Sumihiro, JAYAKUMAR, Honnappa, TEEGARDEN, Bradley R, NOWLIN, Dawn M, CARDARELLI, Pina M, MAH, Jason R

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Biogenesis of the Red Blood Cell Membrane-Skeleton and the Control of Erythroid Morphogenesis by Lazarides, E, Woods, C

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