Search Results - "LAWLER, R"

Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2 by Lawler, Patrick R, Lawler, Jack

“…Thrombospondins TSP-1 and TSP-2 are potent endogenous inhibitors of angiogenesis. They inhibit angiogenesis through direct effects on endothelial cell…”
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Efficacy of exercise-based cardiac rehabilitation post–myocardial infarction: A systematic review and meta-analysis of randomized controlled trials by Lawler, Patrick R., MD, Filion, Kristian B., PhD, Eisenberg, Mark J., MD, MPH

“…Background Exercise-based cardiac rehabilitation (CR) remains an underused tool for secondary prevention post–myocardial infarction (MI). In part, this arises…”
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Targeting cardiovascular inflammation: next steps in clinical translation by Lawler, Patrick R, Bhatt, Deepak L, Godoy, Lucas C, Lüscher, Thomas F, Bonow, Robert O, Verma, Subodh, Ridker, Paul M

“…Abstract Systemic vascular inflammation plays multiple maladaptive roles which contribute to the progression and destabilization of atherosclerotic…”
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Association of anticoagulation dose and survival in hospitalized COVID‐19 patients: A retrospective propensity score‐weighted analysis by Ionescu, Filip, Jaiyesimi, Ishmael, Petrescu, Ioana, Lawler, Patrick R, Castillo, Edward, Munoz‐Maldonado, Yolanda, Imam, Zaid, Narasimhan, Mangala, Abbas, Amr E., Konde, Anish, Nair, Girish B.

“…Background Hypercoagulability may contribute to COVID‐19 pathogenicity. The role of anticoagulation (AC) at therapeutic (tAC) or prophylactic doses (pAC) is…”
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Circulating Branched-Chain Amino Acids and Incident Cardiovascular Disease in a Prospective Cohort of US Women by Tobias, Deirdre K, Lawler, Patrick R, Harada, Paulo H, Demler, Olga V, Ridker, Paul M, Manson, JoAnn E, Cheng, Susan, Mora, Samia

“…Circulating branched-chain amino acids (BCAAs; isoleucine, leucine, and valine) are strong predictors of type 2 diabetes mellitus (T2D), but their association…”
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Prevalent diabetes and long-term cardiovascular outcomes in adult sepsis survivors: a population-based cohort study by Angriman, Federico, Lawler, Patrick R, Shah, Baiju R, Martin, Claudio M, Scales, Damon C

“…Sepsis survivors are at elevated risk for cardiovascular disease during long-term follow-up. Whether diabetes influences cardiovascular risk after sepsis…”
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Hypertriglyceridemia and cardiovascular risk: a cautionary note about metabolic confounding by Sniderman, Allan D., Couture, Patrick, Martin, Seth S., DeGraaf, Jacqueline, Lawler, Patrick R., Cromwell, William C., Wilkins, John T., Thanassoulis, George

“…Triglycerides are the conventional tool to measure VLDLs, whereas LDL cholesterol (LDL-C) is the conventional tool to measure LDLs. Multiple epidemiological…”
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Anemia and mortality in acute coronary syndromes: A systematic review and meta-analysis by Lawler, Patrick R., MD, Filion, Kristian B., PhD, Dourian, Tara, BA, Atallah, Renée, MSc, Garfinkle, Michael, BSc, Eisenberg, Mark J., MD, MPH, FAHA, FACC

“…Background Anemia is a common comorbidity among patients with acute coronary syndromes (ACS) and may adversely affect cardiovascular outcomes in these…”
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Discordance between Circulating Atherogenic Cholesterol Mass and Lipoprotein Particle Concentration in Relation to Future Coronary Events in Women by Lawler, Patrick R, Akinkuolie, Akintunde O, Ridker, Paul M, Sniderman, Allan D, Buring, Julie E, Glynn, Robert J, Chasman, Daniel I, Mora, Samia

“…It is uncertain whether measurement of circulating total atherogenic lipoprotein particle cholesterol mass [non-HDL cholesterol (nonHDLc)] or particle…”
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Cancer risk related to low-dose ionizing radiation from cardiac imaging in patients after acute myocardial infarction by Eisenberg, Mark J, Afilalo, Jonathan, Lawler, Patrick R, Abrahamowicz, Michal, Richard, Hugues, Pilote, Louise

“…Patients exposed to low-dose ionizing radiation from cardiac imaging and therapeutic procedures after acute myocardial infarction may be at increased risk of…”
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The long lives of primates and the ‘invariant rate of ageing’ hypothesis by Colchero, Fernando, Aburto, José Manuel, Archie, Elizabeth A., Boesch, Christophe, Breuer, Thomas, Campos, Fernando A., Collins, Anthony, Conde, Dalia A., Cords, Marina, Crockford, Catherine, Thompson, Melissa Emery, Fedigan, Linda M., Fichtel, Claudia, Groenenberg, Milou, Hobaiter, Catherine, Kappeler, Peter M., Lawler, Richard R., Lewis, Rebecca J., Machanda, Zarin P., Manguette, Marie L., Muller, Martin N., Packer, Craig, Parnell, Richard J., Perry, Susan, Pusey, Anne E., Robbins, Martha M., Seyfarth, Robert M., Silk, Joan B., Staerk, Johanna, Stoinski, Tara S., Stokes, Emma J., Strier, Karen B., Strum, Shirley C., Tung, Jenny, Villavicencio, Francisco, Wittig, Roman M., Wrangham, Richard W., Zuberbühler, Klaus, Vaupel, James W., Alberts, Susan C.

“…Is it possible to slow the rate of ageing, or do biological constraints limit its plasticity? We test the ‘invariant rate of ageing’ hypothesis, which posits…”
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Cardiogenic shock teams and centres: a contemporary review of multidisciplinary care for cardiogenic shock by Moghaddam, Nima, Diepen, Sean, So, Derek, Lawler, Patrick R., Fordyce, Christopher B.

“…Cardiogenic shock (CS) portends high morbidity and mortality in the contemporary era. Despite advances in temporary mechanical circulatory supports (MCS),…”
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Circulating N-Linked Glycoprotein Acetyls and Longitudinal Mortality Risk by Lawler, Patrick R, Akinkuolie, Akintunde O, Chandler, Paulette D, Moorthy, M Vinayaga, Vandenburgh, Martin J, Schaumberg, Debra A, Lee, I-Min, Glynn, Robert J, Ridker, Paul M, Buring, Julie E, Mora, Samia

“…RATIONALE:Circulating glycoprotein N-acetyl glucosamine residues have recently been associated with incident cardiovascular disease and diabetes mellitus…”
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Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality by Shin, Sheojung, Austin, Peter C., Ross, Heather J., Abdel‐Qadir, Husam, Freitas, Cassandra, Tomlinson, George, Chicco, Davide, Mahendiran, Meera, Lawler, Patrick R., Billia, Filio, Gramolini, Anthony, Epelman, Slava, Wang, Bo, Lee, Douglas S.

“…Aims This study aimed to review the performance of machine learning (ML) methods compared with conventional statistical models (CSMs) for predicting…”
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Fasting status and metabolic health in relation to plasma branched chain amino acid concentrations in women by Tobias, Deirdre K., Mora, Samia, Verma, Subodh, Billia, Filio, Buring, Julie E., Lawler, Patrick R.

“…Circulating branched chain amino acids (BCAA) are associated with cardiometabolic risk, although the mechanisms leading to their accumulation remain uncertain…”
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Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort by Soussi, Sabri, Sharma, Divya, Jüni, Peter, Lebovic, Gerald, Brochard, Laurent, Marshall, John C, Lawler, Patrick R, Herridge, Margaret, Ferguson, Niall, Del Sorbo, Lorenzo, Feliot, Elodie, Mebazaa, Alexandre, Acton, Erica, Kennedy, Jason N, Xu, Wei, Gayat, Etienne, Dos Santos, Claudia C

“…Late mortality risk in sepsis-survivors persists for years with high readmission rates and low quality of life. The present study seeks to link the clinical…”
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Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low‐Density Lipoprotein Cholesterol by Lawler, Patrick R., Akinkuolie, Akintunde O., Chu, Audrey Y., Shah, Svati H., Kraus, William E., Craig, Damian, Padmanabhan, Latha, Glynn, Robert J., Ridker, Paul M, Chasman, Daniel I., Mora, Samia

“…Background Levels of LDL (low‐density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual…”
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Palatability mapping: a koala's eye view of spatial variation in habitat quality by Moore, Ben D., Lawler, Ivan R., Wallis, Ian R., Beale, Colin M., Foley, William J.

“…Ecologists trying to understand the value of habitat to animals must first describe the value of resources contained in the habitat to animals and, second,…”
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Determinants of the pathways of litter chemical decomposition in a tropical region by Parsons, Scott A, Congdon, Robert A, Lawler, Ivan R

“…Litter decomposition is a key ecosystem process, yet our understanding of the drivers in chemical changes in leaves during decay is limited. Our aim was to…”
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Residual Risk of Atherosclerotic Cardiovascular Events in Relation to Reductions in Very‐Low‐Density Lipoproteins by Lawler, Patrick R., Akinkuolie, Akintunde O., Harada, Paulo, Glynn, Robert J., Chasman, Daniel I., Ridker, Paul M, Mora, Samia

“…Background It is uncertain whether pharmacological reductions in very‐low‐density lipoproteins (VLDLs), and their component triglyceride and cholesterol could…”
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