Search Results - "LAW, B. K. B"

Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition by Lin, T, Ponn, A, Hu, X, Law, B K, Lu, J

“…Epithelial-mesenchymal transition (EMT) has pivotal roles during embryonic development and carcinoma progression. Members of the Snai1 family of zinc finger…”
Get full text

Metaplastic carcinoma of the breast: a clinicopathological review by Tse, G M, Tan, P H, Putti, T C, Lui, P C W, Chaiwun, B, Law, B K B

“…Background: Mammary metaplastic carcinoma encompasses epithelial-only carcinoma (high-grade adenosquamous carcinoma or pure squamous cell carcinoma), biphasic…”
Get full text

Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms by Law, M E, Corsino, P E, Jahn, S C, Davis, B J, Chen, S, Patel, B, Pham, K, Lu, J, Sheppard, B, Nørgaard, P, Hong, J, Higgins, P, Kim, J-S, Luesch, H, Law, B K

“…Aggressive cancers often express E-cadherin in cytoplasmic vesicles rather than on the plasma membrane and this may contribute to the invasive phenotype of…”
Get full text

Keratin expression in breast cancers by Shao, Mu-Min, Chan, Siu Ki, Yu, Alex M. C., Lam, Christopher C. F., Tsang, Julia Y. S., Lui, Philip C. W., Law, Bonita K. B., Tan, Puay-Hoon, Tse, Gary M.

“…Cytokeratin (CK) immunohistochemistry can play an important role in breast carcinoma evaluation. We evaluated the expression of a panel of commonly used CKs in…”
Get full text

The role of immunohistochemistry for smooth-muscle actin, p63, CD10 and cytokeratin 14 in the differential diagnosis of papillary lesions of the breast by Tse, G M K, Tan, P-H, Lui, P C W, Gilks, C B, Poon, C S P, Ma, T K F, Law, B K B, Lam, W W M

“…Background: Histological differentiation of mammary papillary lesions can be difficult. The evaluation of myoepithelial cells can be helpful, with benign…”
Get full text

Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner by Biel, T G, Lee, S, Flores-Toro, J A, Dean, J W, Go, K L, Lee, M-H, Law, B K, Law, M E, Dunn, W A, Zendejas, I, Behrns, K E, Kim, J-S

Get full text

Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM ATR signaling pathway by MCCONNELL, J. L, GOMEZ, R. J, MCCORVEY, L. R. A, LAW, B. K, WADZINSKI, B. E

“…Protein serine/threonine phosphatase 2A (PP2A) activity must be tightly controlled to maintain cell homeostasis. Here, we report the identification of a…”
Get full text

Lymphocytic infiltrate is associated with favorable biomarkers profile in HER2-overexpressing breast cancers and adverse biomarker profile in ER-positive breast cancers by Tsang, Julia Y. S., Hui, Suen-Wah, Ni, Yun-Bi, Chan, Siu-Ki, Yamaguchi, Rin, Kwong, Ava, Law, Bonita K. B., Tse, Gary M.

“…The value for lymphocytic infiltration (LI) has been increasingly recognized for tumor assessment. In breast cancer, however, the overall significance of LI…”
Get full text

Routine use of laparoscopic repair for perforated peptic ulcer by Siu, W. T., Chau, C. H., Law, B. K. B., Tang, C. N., Ha, P. Y., Li, M. K. W.

“…Background: Laparoscopic repair of perforated peptic ulcer was reported in 1990 but has not gained wide acceptance. The aim of this study was to evaluate the…”
Get full text

Multifocal "tapete" papillary fibroelastoma by Law, K B, Phillips, K R B, Cusimano, R J, Butany, J

“…Papillary fibroelastomas (PFEs) are benign cardiac tumours that typically arise on diseased aortic or mitral valves. Usually solitary, PFEs are characterised…”
Get more information

Requirement of the histone demethylase LSD1 in Snail-mediated transcriptional repression during epithelial-mesenchymal transition by LIN, T, PONN, A, HU, X, LAW, B. K, LU, J

“…Epithelial-mesenchymal transition (EMT) has pivotal roles during embryonic development and carcinoma progression. Members of the Snai1 family of zinc finger…”
Get full text

Androgen Receptor Expression Shows Distinctive Significance in ER Positive and Negative Breast Cancers by Tsang, Julia Y. S., Ni, Yun-Bi, Chan, Siu-Ki, Shao, Mu-Min, Law, Bonita K. B., Tan, Puay Hoon, Tse, Gary M.

“…Background Androgen receptor (AR), a nuclear steroid hormone receptor, is differentially expressed in breast cancer subgroups with distinct clinical…”
Get full text

Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner by Biel, T G, Lee, S, Flores-Toro, J A, Dean, J W, Go, K L, Lee, M-H, Law, B K, Law, M E, Dunn, W A, Zendejas, I, Behrns, K E, Kim, J-S

“…Ischemia/reperfusion (I/R) injury is a major cause of morbidity and mortality after liver surgery. The role of Sirtuin 1 (SIRT1) in hepatic I/R injury remains…”
Get full text

Micro- and nano-topography to enhance proliferation and sustain functional markers of donor-derived primary human corneal endothelial cells by Muhammad, Rizwan, Peh, Gary S.L., Adnan, Khadijah, Law, Jaslyn B.K., Mehta, Jodhbir S., Yim, Evelyn K.F.

“…[Display omitted] One of the most common indications for corneal transplantation is corneal endothelium dysfunction, which can lead to corneal blindness. Due…”
Get full text

Relationship between glutathione S-transferase gene polymorphisms and enzyme activity in Hong Kong Chinese asthmatics by Mak, J. C. W., Ho, S. P., Leung, H. C. M., Cheung, A. H. K., Law, B. K. W., So, L. K. Y., Chan, J. W. M., Chau, C. H., Lam, W. K., Ip, M. S. M., Chan-Yeung, M.

“…Summary Background Asthma is a disease associated with oxidative stress. The glutathione S‐transferases (GST) are a group of enzymes that protect cells from…”
Get full text

Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells by Wong, V KW, Li, T, Law, B YK, Ma, E DL, Yip, N C, Michelangeli, F, Law, C KM, Zhang, M M, Lam, K YC, Chan, P L, Liu, L

“…Autophagy is an important cellular process that controls cells in a normal homeostatic state by recycling nutrients to maintain cellular energy levels for cell…”
Get full text

MR Imaging Criteria for the Detection of Nasopharyngeal Carcinoma: Discrimination of Early-Stage Primary Tumors from Benign Hyperplasia by King, A D, Wong, L Y S, Law, B K H, Bhatia, K S, Woo, J K S, Ai, Q-Y, Tan, T Y, Goh, J, Chuah, K L, Mo, F K F, Chan, K C A, Chan, A T C, Vlantis, A C

“…MR imaging can detect nasopharyngeal carcinoma that is hidden from endoscopic view, but for accurate detection carcinoma confined within the nasopharynx (stage…”
Get full text

Signaling cross-talk between IGF-binding protein-3 and transforming growth factor-β in mesenchymal chondroprogenitor cell growth by O’Rear, L, Longobardi, L, Torello, M, Law, B K, Moses, H L, Chiarelli, F, Spagnoli, A

“…Cartilage formation is driven by mesenchymal chondroprogenitor cells (MCCs) that proliferate and differentiate into chondrocytes. The molecular mechanisms by…”
Get full text

Detection of Nasopharyngeal Carcinoma by MR Imaging: Diagnostic Accuracy of MRI Compared with Endoscopy and Endoscopic Biopsy Based on Long-Term Follow-Up by King, A D, Vlantis, A C, Yuen, T W C, Law, B K H, Bhatia, K S, Zee, B C Y, Woo, J K S, Chan, A T C, Chan, K C A, Ahuja, A T

“…Our previous nasopharyngeal carcinoma detection study, comparing MR imaging, endoscopy, and endoscopic biopsy, showed that MR imaging is a highly sensitive…”
Get full text

Laparoscopic repair for perforated peptic ulcer: A randomized controlled trial by SIU, Wing T, LEONG, Heng T, LAW, Bonita K. B, CHAU, Chun H, LI, Anthony C. N, FUNG, Kai H, TAI, Yuk P, LI, Michael K. W

“…To compare the results of open versus laparoscopic repair for perforated peptic ulcers. Omental patch repair with peritoneal lavage is the mainstay of…”
Get full text