Search Results - "LAVOIE, Julie L"
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Minireview: Overview of the Renin-Angiotensin System—An Endocrine and Paracrine System
Published in Endocrinology (Philadelphia) (01-06-2003)“…Since the discovery of renin as a pressor substance in 1898, the renin-angiotensin (RAS) system has been extensively studied because it remains a prime…”
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A Longitudinal Pilot Study on Cognition and Cerebral Hemodynamics in a Mouse Model of Preeclampsia Superimposed on Hypertension: Looking at Mothers and Their Offspring
Published in Frontiers in physiology (01-02-2021)“…Preeclampsia is a common hypertensive disorder in pregnant women and whose causes and consequences have focused primarily on cardiovascular outcomes on the…”
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Post‐exercise hypotension in male spontaneously hypertensive rats: The issue of calculation method
Published in Physiological reports (01-02-2023)“…In spontaneously hypertensive rats, exercise can lead to a post‐exercise decrease in blood pressure, named post‐exercise hypotension (PEH). This can be…”
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Impact of the prorenin/renin receptor on the development of obesity and associated cardiometabolic risk factors
Published in Obesity (Silver Spring, Md.) (01-10-2014)“…Objective Obesity is a worldwide epidemic and current treatments have limited success thus, novel therapies are warranted. Our objective was to determine…”
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Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight
Published in Molecular metabolism (Germany) (01-10-2016)“…Abstract Objective We previously demonstrated that the handle-region peptide, a prorenin/renin receptor [(P)RR] blocker, reduces body weight and fat mass and…”
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(Pro)renin receptor as a new drug target
Published in Current pharmaceutical design (01-11-2011)“…Over the last few years, the implication of the (pro)renin receptor [(P)RR] in the pathogenesis of end-organ damage has been shown through many different…”
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Possible Role of Efnb1 Protein, a Ligand of Eph Receptor Tyrosine Kinases, in Modulating Blood Pressure
Published in The Journal of biological chemistry (04-05-2012)“…Eph kinases constitute the largest receptor tyrosine kinase family, and their ligands, ephrins (Efns), are also cell surface molecules. Although they are…”
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Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1
Published in PLoS genetics (01-02-2014)“…The potent vasoconstrictor peptides, endothelin 1 (ET-1) and angiotensin II control adaptation of blood vessels to fluctuations of blood pressure. Previously…”
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Mice Overexpressing Both Human Angiotensinogen and Human Renin as a Model of Superimposed Preeclampsia on Chronic Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-12-2009)“…Preeclampsia is the major cause of maternal and fetal mortality/morbidity. Because hypertension is an important risk factor for preeclampsia, we investigated…”
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Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule
Published in American journal of physiology. Renal physiology (01-05-2004)“…The purpose of this study was to evaluate the physiological significance of a tissue renin-angiotensin system in the proximal tubule of the kidney. To…”
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Evidence Supporting a Functional Role for Intracellular Renin in the Brain
Published in Hypertension (Dallas, Tex. 1979) (01-03-2006)“…The brain renin–angiotensin system is implicated in the regulation of blood pressure (BP) and fluid homeostasis. Recent studies reveal that 2 forms of renin…”
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Hyperhomocysteinemia is not sufficient to cause preeclampsia in an animal model: the importance of folate intake
Published in American journal of obstetrics and gynecology (01-02-2009)“…Objective The objective of our study was to determine whether methylenetetrahydrofolate reductase (Mthfr)-deficient mice develop preeclampsia (PE). Study…”
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Adjacent Expression of Renin and Angiotensinogen in the Rostral Ventrolateral Medulla Using a Dual-Reporter Transgenic Model
Published in Hypertension (Dallas, Tex. 1979) (01-05-2004)“…ABSTRACT—All components of the renin-angiotensin system are localized in the brain. However, because renin is present in very low concentrations, the mechanism…”
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Impact of Exercise Training on Preeclampsia: Potential Preventive Mechanisms
Published in Hypertension (Dallas, Tex. 1979) (01-11-2012)“…Preeclampsia is characterized by hypertension and de novo proteinuria after 20 weeks of pregnancy. It is the leading cause of perinatal morbidity and mortality…”
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Development of Hypertension and Kidney Hypertrophy in Transgenic Mice Overexpressing ARAP1 Gene in the Kidney
Published in Hypertension (Dallas, Tex. 1979) (01-09-2006)“…Angiotensin II regulates blood pressure via activation of the type 1 receptor. We previously identified a novel angiotensin II type 1 receptor–associated…”
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Impact of diet and stress on the development of preeclampsia-like symptoms in p57kip2 mice
Published in American journal of physiology. Heart and circulatory physiology (01-01-2009)“…The cyclin-dependent kinase inhibitor p57(kip2) regulates the cell cycle of trophoblastic cells. It has been established by a Japanese group that the…”
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Contribution of -1031T/C and -376G/A tumor necrosis factor alpha polymorphisms and haplotypes to preeclampsia risk in Tunisia (North Africa)
Published in Journal of reproductive immunology (01-02-2022)“…•The minor allele TNF-α -1031C polymorphism is associated with preeclampsia.•-1031C and -376A (CA) haplotype was associated with a higher incidence of…”
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Mouse Adipose Tissue Collection and Processing for RNA Analysis
Published in Journal of visualized experiments (31-01-2018)“…Compared to other tissues, white adipose tissue has a considerably less RNA and protein content for downstream applications such as real-time PCR and Western…”
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EPHB4 Protein Expression in Vascular Smooth Muscle Cells Regulates Their Contractility, and EPHB4 Deletion Leads to Hypotension in Mice
Published in The Journal of biological chemistry (29-05-2015)“…EPH kinases are the largest family of receptor tyrosine kinases, and their ligands, ephrins (EFNs), are also cell surface molecules. This work presents…”
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