Search Results - "LAURENT, Benoit"
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APOE and Alzheimer's Disease: From Lipid Transport to Physiopathology and Therapeutics
Published in Frontiers in neuroscience (17-02-2021)“…Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations…”
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Lipid Transport and Metabolism at the Blood-Brain Interface: Implications in Health and Disease
Published in Frontiers in physiology (30-03-2021)“…Many prospective studies have shown that a diet enriched in omega-3 polyunsaturated fatty acids (n-3 PUFAs) can improve cognitive function during normal aging…”
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Exploring the Alternative Splicing of Long Noncoding RNAs
Published in Trends in genetics (01-08-2021)“…Like protein-coding genes, long noncoding RNA (lncRNA) genes are composed of introns and exons. After their transcription, lncRNAs are subject to constitutive…”
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AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions
Published in Nature cell biology (01-02-2019)“…Aberrant activation of AKT disturbs the proliferation, survival and metabolic homeostasis of various human cancers. Thus, it is critical to understand the…”
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Quantitative study of the mineralogical composition of mineral dust aerosols by X-ray diffraction
Published in Talanta (Oxford) (15-08-2018)“…Mineral dust aerosols, produced by wind erosion in arid regions and semi-arid surfaces, are important components of the atmosphere that affect the Earth…”
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LAMP for in‐field quantitative assessments of airborne grapevine downy mildew inoculum
Published in Journal of applied microbiology (01-12-2022)“…Aims Cheap, rapid tools for measuring emissions of Plasmopara viticola sporangia directly in the field are required to protect grapevines efficiently and…”
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A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation
Published in Molecular cell (19-03-2015)“…Lysine-specific demethylase 1 (LSD1) has been reported to repress and activate transcription by mediating histone H3K4me1/2 and H3K9me1/2 demethylation,…”
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Landscape of genomic diversity and host adaptation in Fusarium graminearum
Published in BMC genomics (23-02-2017)“…Fusarium graminearum is one of the main causal agents of the Fusarium Head Blight, a worldwide disease affecting cereal cultures, whose presence can lead to…”
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Downregulation of ribosome biogenesis during early forebrain development
Published in eLife (10-05-2018)“…Forebrain precursor cells are dynamic during early brain development, yet the underlying molecular changes remain elusive. We observed major differences in…”
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Intra-event evolution of elemental and ionic concentrations in wet deposition in an urban environment
Published in Atmospheric chemistry and physics (25-10-2023)“…A measurement campaign was conducted in the Paris region, focusing on the evolution of chemical composition of wet deposition during rainfall events from…”
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Distinct regulatory functions and biological roles of lncRNA splice variants
Published in Molecular therapy. Nucleic acids (13-06-2023)“…Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In humans, 90%–95% of multi-exon genes produce alternatively…”
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Detection of early-universe gravitational-wave signatures and fundamental physics
Published in General relativity and gravitation (2022)“…Detection of a gravitational-wave signal of non-astrophysical origin would be a landmark discovery, potentially providing a significant clue to some of our…”
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JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors
Published in Genes & development (15-10-2015)“…RUNX1-RUNX1T1 (formerly AML1-ETO), a transcription factor generated by the t(8;21) translocation in acute myeloid leukemia (AML), dictates a leukemic program…”
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High‐resolution mapping of the recombination landscape of the phytopathogen Fusarium graminearum suggests two‐speed genome evolution
Published in Molecular plant pathology (01-02-2018)“…Summary Recombination is a major evolutionary force, increasing genetic diversity and permitting efficient coevolution of fungal pathogen(s) with their…”
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In Vitro Assessment of the Neuroprotective Effects of Pomegranate (Punica granatum L.) Polyphenols Against Tau Phosphorylation, Neuroinflammation, and Oxidative Stress
Published in Nutrients (01-11-2024)“…Background: Oxidative stress and chronic inflammation, at both the systemic and the central level, are critical early events in atherosclerosis and Alzheimer’s…”
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Transcriptomic modulation in response to high-intensity interval training in monocytes of older women with type 2 diabetes
Published in European journal of applied physiology (01-04-2022)“…Purpose Type 2 diabetes is associated with a higher risk of cardiovascular diseases, lowering the quality of life and increasing mortality rates of affected…”
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A New Open-Source Software to Help Design Models for Automatic 3D Point Cloud Classification in Coastal Studies
Published in Remote sensing (Basel, Switzerland) (01-08-2024)“…This study introduces a new software, cLASpy_T, that helps design models for the automatic 3D point cloud classification of coastal environments. This software…”
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Efficient generation of human induced pluripotent stem cells from urine samples of patients with Fragile X syndrome
Published in Frontiers in cell and developmental biology (22-11-2024)“…Human induced pluripotent stem cells (iPSCs) are a valuable tool for studying human development and diseases. iPSCs can be generated by reprogramming from any…”
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Re-evaluating the impact of alternative RNA splicing on proteomic diversity
Published in Frontiers in genetics (09-02-2023)“…Alternative splicing (AS) constitutes a mechanism by which protein-coding genes and long non-coding RNA (lncRNA) genes produce more than a single mature…”
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Estimating chemical composition of atmospheric deposition fluxes from mineral insoluble particles deposition collected in the western Mediterranean region
Published in Atmospheric measurement techniques (15-11-2017)“…In order to measure the mass flux of atmospheric insoluble deposition and to constrain regional models of dust simulation, a network of automatic deposition…”
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