Search Results - "LAU, Derick"

Phase III Trial of Maintenance Gefitinib or Placebo After Concurrent Chemoradiotherapy and Docetaxel Consolidation in Inoperable Stage III Non–Small-Cell Lung Cancer: SWOG S0023 by KELLY, Karen, CHANSKY, Kari, GASPAR, Laurie E, ALBAIN, Kathy S, JETT, James, UNG, Yee C, LAU, Derick H. M, CROWLEY, John J, GANDARA, David R

“…Early clinical studies with gefitinib showed promising efficacy and mild toxicity in patients with advanced non-small-cell lung cancer (NSCLC). Thus, gefitinib…”
Get full text

Evaluating the Role of Prophylactic Gastrostomy Tube Placement Prior to Definitive Chemoradiotherapy for Head and Neck Cancer by Chen, Allen M., M.D, Li, Bao-Qing, M.D., Ph.D, Lau, Derick H., M.D., Ph.D, Farwell, D. Gregory, M.D, Luu, Quang, M.D, Stuart, Kerri, R.N, Newman, Kathleen, R.D, Purdy, James A., Ph.D, Vijayakumar, Srinivasan, M.D

“…Purpose To determine the effect of prophylactic gastrostomy tube (GT) placement on acute and long-term outcome for patients treated with definitive…”
Get full text

Tobacco Smoking During Radiation Therapy for Head-and-Neck Cancer Is Associated With Unfavorable Outcome by Chen, Allen M., M.D, Chen, Leon M., M.D, Vaughan, Andrew, Ph.D, Sreeraman, Radhika, B.A, Farwell, D. Gregory, M.D, Luu, Quang, M.D, Lau, Derick H., M.D., Ph.D, Stuart, Kerri, R.N, Purdy, James A., Ph.D, Vijayakumar, Srinivasan, M.D

“…Purpose To evaluate the effect of continued cigarette smoking among patients undergoing radiation therapy for head-and-neck cancer by comparing the clinical…”
Get full text

Brachial Plexus-Associated Neuropathy After High-Dose Radiation Therapy for Head-and-Neck Cancer by Chen, Allen M., M.D, Hall, William H., M.D, Li, Judy, Ph.D, Beckett, Laurel, Ph.D, Farwell, D. Gregory, M.D, Lau, Derick H., M.D., Ph.D, Purdy, James A., Ph.D

“…Purpose To identify clinical and treatment-related predictors of brachial plexus–associated neuropathies after radiation therapy for head-and-neck cancer…”
Get full text

Intensity-Modulated Radiotherapy is Associated With Improved Global Quality of Life Among Long-term Survivors of Head-and-Neck Cancer by Chen, Allen M., M.D, Farwell, D. Gregory, M.D, Luu, Quang, M.D, Vazquez, Esther G., R.N, Lau, Derick H., M.D., Ph.D, Purdy, James A., Ph.D

“…Purpose To compare the long-term quality of life among patients treated with and without intensity-modulated radiotherapy (IMRT) for head-and-neck cancer…”
Get full text

Quality of life among long-term survivors of head and neck cancer treated by intensity-modulated radiotherapy by Chen, Allen M, Daly, Megan E, Farwell, D Gregory, Vazquez, Esther, Courquin, Jean, Lau, Derick H, Purdy, James A

“…Radiation therapy to the head and neck has traditionally been associated with adverse effects that can affect oral health and physical functioning. Although…”
Get more information

Radiation Therapy in the Management of Head-and-Neck Cancer of Unknown Primary Origin: How Does the Addition of Concurrent Chemotherapy Affect the Therapeutic Ratio? by Chen, Allen M., M.D, Farwell, D. Gregory, M.D, Lau, Derick H., M.D., Ph.D, Li, Bao-Qing, M.D., Ph.D, Luu, Quang, M.D, Donald, Paul J., M.D

“…Purpose To determine how the addition of cisplatin-based concurrent chemotherapy to radiation therapy influences outcomes among a cohort of patients treated…”
Get full text

Gefitinib Therapy in Advanced Bronchioloalveolar Carcinoma: Southwest Oncology Group Study S0126 by WEST, Howard L, FRANKLIN, Wilbur A, MCCOY, Jason, GUMERLOCK, Paul H, VANCE, Ralph, LAU, Derick H. M, CHANSKY, Kari, CROWLEY, John J, GANDARA, David R

“…Advanced bronchioloalveolar carcinoma (BAC) is a distinct subtype of non-small-cell lung cancer (NSCLC) for which there is currently no optimal therapy. Based…”
Get full text

Clinical-dosimetric analysis of measures of dysphagia including gastrostomy-tube dependence among head and neck cancer patients treated definitively by intensity-modulated radiotherapy with concurrent chemotherapy by Li, Baoqing, Li, Dan, Lau, Derick H, Farwell, D Gregory, Luu, Quang, Rocke, David M, Newman, Kathleen, Courquin, Jean, Purdy, James A, Chen, Allen M

“…To investigate the association between dose to various anatomical structures and dysphagia among patients with head and neck cancer treated by definitive…”
Get full text

Phase III Trial of Paclitaxel Plus Carboplatin With or Without Tirapazamine in Advanced Non–Small-Cell Lung Cancer: Southwest Oncology Group Trial S0003 by WILLIAMSON, Stephen K, CROWLEY, John J, LARA, Primo N, MCCOY, Jason, LAU, Derick H. M, TUCKER, Robert W, MILLS, Glenn M, GANDARA, David R

“…Tumor hypoxia confers chemotherapy resistance. Tirapazamine is a cytotoxin that selectively targets hypoxic cells. We conducted a phase III clinical trial to…”
Get full text

Feasibility and toxicity of concurrent chemoradiation for elderly patients with head and neck cancer by Daly, Megan E., MD, Lau, Derick H., MD, Farwell, D. Gregory, MD, Luu, Quang, MD, Donald, Paul J., MD, Chen, Allen M., MD

“…Abstract Objectives Although concurrrent chemoradiation is increasingly used for patients with locally advanced head and neck cancer, many elderly patients…”
Get full text

Differential response rates to irradiation among patients with human papillomavirus positive and negative oropharyngeal cancer by Chen, Allen M., Li, Judy, Beckett, Laurel A., Zhara, Talia, Farwell, Gregory, Lau, Derick H., Gandour-Edwards, Regina, Vaughan, Andrew T., Purdy, James A.

“…Objectives/Hypothesis: To evaluate the responsiveness of human papillomavirus (HPV) ‐positive and HPV‐negative oropharyngeal cancer to intensity‐modulated…”
Get full text

Prospective Evaluation of Cancer Clinical Trial Accrual Patterns: Identifying Potential Barriers to Enrollment by Lara, Jr, P N, Higdon, R, Lim, N, Kwan, K, Tanaka, M, Lau, D H, Wun, T, Welborn, J, Meyers, F J, Christensen, S, O'Donnell, R, Richman, C, Scudder, S A, Tuscano, J, Gandara, D R, Lam, K S

“…Well-conducted cancer clinical trials are essential for improving patient outcomes. Unfortunately, only 3% of new cancer patients participate in clinical…”
Get full text

Southwestern Oncology Group Phase II Trial (S0526) of Pemetrexed in Bronchioloalveolar Carcinoma Subtypes of Advanced Adenocarcinoma by Lau, Derick H.M, Moon, James, Davies, Angela M, Sanborn, Rachel E, Hirsch, Fred R, Franklin, Wilbur A, Ruzich, Janet C, Redman, Mary W, Gandara, David R

“…Micro-Abstract Bronchioloalveolar carcinoma (BAC) subtypes of lung adenocarcinoma represent approximately 10% to 15% of new non–small-cell lung cancer cases…”
Get full text

Late esophageal toxicity after radiation therapy for head and neck cancer by Chen, Allen M., Li, Bao-Qing, Jennelle, Richard L. S., Lau, Derick H., Yang, Claus C., Courquin, Jean, Vijayakumar, Srinivasan, Purdy, James A.

“…Background. The aim of this study was to determine the incidence of esophageal toxicity after radiation therapy for head and neck cancer. Methods. The records…”
Get full text

Phase II Study of Consolidation Paclitaxel After Concurrent Chemoradiation in Poor-Risk Stage III Non–Small-Cell Lung Cancer: SWOG S9712 by DAVIES, Angela M, CHANSKY, Kari, LAU, Derick H. M, LEIGH, Bryan R, GASPAR, Laurie E, WEISS, Geoffrey R, WOZNIAK, Antoinette J, CROWLEY, John J, GANDARA, David R

“…A previous Southwest Oncology Group (SWOG) study (S9429) demonstrated efficacy and tolerability of concurrent chemoradiotherapy in poor-risk stage III…”
Get full text

Identification of novel targeting peptides for human ovarian cancer cells using “one-bead one-compound” combinatorial libraries by Aina, Olulanu H, Marik, Jan, Liu, Ruiwu, Lau, Derick H, Lam, Kit S

“…Using “one-bead one-compound” combinatorial chemistry technology, we generated random peptide libraries containing millions of 90 μm TentaGel beads, each with…”
Get full text

Advances in positron emission tomography technology have increased the need for surgical staging in non–small cell lung cancer by Lee, Benjamin Enoch, MD, von Haag, Derek, MD, Lown, Teri, RN, OCN, Lau, Derick, MD, PhD, Calhoun, Royce, MD, Follette, David, MD

“…Objectives Pretreatment staging of patients with non–small cell lung cancer is critically important in determining an appropriate treatment plan. As positron…”
Get full text

Randomized Phase II Trial of Concurrent Versus Sequential Bortezomib Plus Docetaxel in Advanced Non–Small-Cell Lung Cancer: A California Cancer Consortium Trial by Lara, Primo N, Longmate, Jeff, Reckamp, Karen, Gitlitz, Barbara, Argiris, Athanassios, Ramalingam, Suresh, Belani, Chandra P, Mack, Philip C, Lau, Derick H.M, Koczywas, Mariana, Wright, John J, Shepherd, Frances A, Leighl, Natasha, Gandara, David R

“…Abstract Background The proteasome inhibitor bortezomib sensitizes tumor cells to chemotherapy-induced apoptosis. In preclinical non–small-cell lung cancer…”
Get full text

Phase II Trial of Irinotecan and Carboplatin for Extensive or Relapsed Small-Cell Lung Cancer by Chen, Gigi, Huynh, Minh, Fehrenbacher, Lou, West, Howard, Lara, Jr, Primo N, Yavorkovsky, Leonid L, Russin, Michael, Goldstein, Desiree, Gandara, David, Lau, Derick

“…The regimens of weekly irinotecan with platinum have been used for treatment of metastatic small-cell lung cancer (SCLC). We conducted a multi-institution…”
Get full text