Search Results - "LASZLO, G"

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients by Brasnyó, Pál, Molnár, Gergő A., Mohás, Márton, Markó, Lajos, Laczy, Boglárka, Cseh, Judit, Mikolás, Esztella, Szijártó, István András, Mérei, Ákos, Halmai, Richárd, Mészáros, László G., Sümegi, Balázs, Wittmann, István

“…Although resveratrol has widely been studied for its potential health benefits, little is known about its metabolic effects in humans. Our aims were to…”
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Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters by Puskás, László G., Kitajka, Klara, Vizler, Csaba, Szebeni, G. J.

“…One of the hallmarks of cancer-related inflammation is the recruitment of monocyte-macrophage lineage cells to the tumor microenvironment. These tumor…”
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Striking Neurochemical and Behavioral Differences in the Mode of Action of Selegiline and Rasagiline by Harsing, Laszlo G, Timar, Julia, Miklya, Ildiko

“…Selegiline and rasagiline are two selective monoamine oxidase B (MAO-B) inhibitors used in the treatment of Parkinson’s disease. In their clinical application,…”
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Glaucoma risk index:Automated glaucoma detection from color fundus images by Bock, Rüdiger, Meier, Jörg, Nyúl, László G., Hornegger, Joachim, Michelson, Georg

“…Glaucoma as a neurodegeneration of the optic nerve is one of the most common causes of blindness. Because revitalization of the degenerated nerve fibers of the…”
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Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides Insights into the Origins of Lignocellulose Decay Capabilities by Nagy, László G, Riley, Robert, Tritt, Andrew, Adam, Catherine, Daum, Chris, Floudas, Dimitrios, Sun, Hui, Yadav, Jagjit S, Pangilinan, Jasmyn, Larsson, Karl-Henrik, Matsuura, Kenji, Barry, Kerrie, Labutti, Kurt, Kuo, Rita, Ohm, Robin A, Bhattacharya, Sukanta S, Shirouzu, Takashi, Yoshinaga, Yuko, Martin, Francis M, Grigoriev, Igor V, Hibbett, David S

“…Evolution of lignocellulose decomposition was one of the most ecologically important innovations in fungi. White-rot fungi in the Agaricomycetes (mushrooms and…”
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Evolution: Complex Multicellular Life with 5,500 Genes by Nagy, Laszlo G.

“…The origin of complex multicellularity was a major transition in evolution and is generally associated with higher genomic complexity. However, some complex…”
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GABAergic neurogliaform cells represent local sources of insulin in the cerebral cortex by Molnár, Gábor, Faragó, Nóra, Kocsis, Ágnes K, Rózsa, Márton, Lovas, Sándor, Boldog, Eszter, Báldi, Rita, Csajbók, Éva, Gardi, János, Puskás, László G, Tamás, Gábor

“…Concentrations of insulin in the brain are severalfold higher than blood plasma levels. Insulin in the brain regulates the metabolism, molecular composition,…”
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Signatures of cell death and proliferation in perturbation transcriptomics data—from confounding factor to effective prediction by Szalai, Bence, Subramanian, Vigneshwari, Holland, Christian H, Alföldi, Róbert, Puskás, László G, Saez-Rodriguez, Julio

“…Abstract Transcriptional perturbation signatures are valuable data sources for functional genomics. Linking perturbation signatures to screenings opens the…”
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Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivity by Weber, Felix C, Németh, Tamás, Csepregi, Janka Z, Dudeck, Anne, Roers, Axel, Ozsvári, Béla, Oswald, Eva, Puskás, László G, Jakob, Thilo, Mócsai, Attila, Martin, Stefan F

“…Allergic contact dermatitis and its animal model, contact hypersensitivity (CHS), are T cell-mediated inflammatory skin diseases induced by contact allergens…”
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The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function by Oberbeck, Nina, Pham, Victoria C., Webster, Joshua D., Reja, Rohit, Huang, Christine S., Zhang, Yue, Roose-Girma, Merone, Warming, Søren, Li, Qingling, Birnberg, Andrew, Wong, Weng, Sandoval, Wendy, Kőműves, László G., Yu, Kebing, Dugger, Debra L., Maltzman, Allie, Newton, Kim, Dixit, Vishva M.

“…The integrity of the mammalian epidermis depends on a balance of proliferation and differentiation in the resident population of stem cells 1 . The kinase…”
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Targeting the cancer mutanome of breast cancer by Radvanyi, Laszlo G.

“…A metastatic hormone receptor–positive breast cancer, usually resistant to immunotherapy, is successfully treated with tumor-infiltrating lymphocytes enriched…”
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Enhancer Regulation of Dopaminergic Neurochemical Transmission in the Striatum by Harsing, Laszlo, Knoll, Joseph, Miklya, Ildiko

“…The trace amine-associated receptor 1 (TAAR1) is a Gs protein-coupled, intracellularly located metabotropic receptor. Trace and classic amines, amphetamines,…”
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Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs by Jost, Norbert, Virág, László, Comtois, Philippe, Ördög, Balázs, Szuts, Viktória, Seprényi, György, Bitay, Miklós, Kohajda, Zsófia, Koncz, István, Nagy, Norbert, Szél, Tamás, Magyar, János, Kovács, Mária, Puskás, László G., Lengyel, Csaba, Wettwer, Erich, Ravens, Ursula, Nánási, Péter P., Papp, Julius Gy, Varró, András, Nattel, Stanley

“…Key points •  Cardiac repolarization, through which heart‐cells return to their resting state after having fired, is a delicate process, susceptible to…”
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Mechanisms of glycine release, which build up synaptic and extrasynaptic glycine levels: The role of synaptic and non-synaptic glycine transporters by Harsing, Laszlo G, Matyus, Peter

“…Highlights ► Glycine can be released from neurons and astroglial cells. ► GlyT-1 carries out bidirectional glycine transport in the synaptic and extrasynaptic…”
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Purinergic–Glycinergic Interaction in Neurodegenerative and Neuroinflammatory Disorders of the Retina by Harsing, Laszlo G., Szénási, Gábor, Zelles, Tibor, Köles, László

“…Neurodegenerative–neuroinflammatory disorders of the retina seriously hamper human vision. In searching for key factors that contribute to the development of…”
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Tumor-Infiltrating Lymphocyte Therapy: Addressing Prevailing Questions by Radvanyi, Laszlo G

“…Autologous adoptive T-cell therapies have made tremendous strides over the last few years with excitement currently being generated by technologies that can…”
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Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi by Riley, Robert, Salamov, Asaf A., Brown, Daren W., Nagy, Laszlo G., Floudas, Dimitrios, Held, Benjamin W., Levasseur, Anthony, Lombard, Vincent, Morin, Emmanuelle, Otillar, Robert, Lindquist, Erika A., Sun, Hui, LaButti, Kurt M., Schmutz, Jeremy, Jabbour, Dina, Luoi, Hong, Baker, Scott E., Pisabarro, Antonio G., Walton, Jonathan D., Blanchette, Robert A., Henrissat, Bernard, Martin, Francis, Cullen, Dan, Hibbett, David S., Grigoriev, Igor V.

“…Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most wood-decaying species, as well as pathogens and mutualistic symbionts…”
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Standardisation of lung function testing: helpful guidance from the ATS/ERS Task Force by Laszlo, G

“…In patients with non-asthmatic COPD the increase in FEV1 and FVC after bronchodilator is more or less normally distributed. 11, 12 Moreover, these increases…”
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Glycine Transporter 1 Inhibitors Minimize the Analgesic Tolerance to Morphine by Galambos, Anna Rita, Essmat, Nariman, Lakatos, Péter P, Szücs, Edina, Boldizsár, Jr, Imre, Abbood, Sarah Kadhim, Karádi, Dávid Á, Kirchlechner-Farkas, Judit Mária, Király, Kornél, Benyhe, Sándor, Riba, Pál, Tábi, Tamás, Harsing, Jr, Laszlo G, Zádor, Ferenc, Al-Khrasani, Mahmoud

“…Opioid analgesic tolerance (OAT), among other central side effects, limits opioids' indispensable clinical use for managing chronic pain. Therefore, there is…”
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Kinetic analysis of the toxicity of pharmaceutical excipients Cremophor EL and RH40 on endothelial and epithelial cells by Kiss, Lóránd, Walter, Fruzsina R, Bocsik, Alexandra, Veszelka, Szilvia, Ozsvári, Béla, Puskás, László G, Szabó-Révész, Piroska, Deli, Mária A

“…Cremophor EL and RH40 are widely used excipients in oral and intravenous drug formulations such as Taxol infusion to improve drug dissolution and absorption…”
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