Search Results - "LASSILA, O."

Embracing "Web 3.0" by Lassila, O., Hendler, J.

“…With the Resource Description Framework (RDF) and Web Ontology Language (OWL) - the languages that power the semantic Web - becoming standards and new…”
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Phenotypic characterization of regulatory T cells in the human decidua by HEIKKINEN, J., MÖTTÖNEN, M., ALANEN, A., LASSILA, O.

“…SUMMARY Pregnancy is a unique situation for the maternal immune system. We have studied and identified a CD4+CD25+ regulatory T (Treg) cell population isolated…”
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Phenotypic characterization of human decidual macrophages by HEIKKINEN, J., MÖTTÖNEN, M., KOMI, J., ALANEN, A., LASSILA, O.

“…Summary Pregnancy is a challenge to the immune system, which not only has to protect the mother and the fetus from invading pathogens but to also maintain…”
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CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis by Möttönen, M., Heikkinen, J., Mustonen, L., Isomäki, P., Luukkainen, R., Lassila, O.

“…Summary CD4+ CD25+ regulatory T (Treg) cells play a critical role in the maintenance of peripheral tolerance and the prevention of autoimmunity. In the present…”
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Gene Interaction Network Regulates Plasma Cell Differentiation by Alinikula, J., Lassila, O.

“…Effective humoral immunity depends on B cells, plasma cells and follicular helper T cells (TFH) and secreted high‐affinity antibodies. The differentiation of…”
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Regulation of B Cell to Plasma Cell Transition within the Follicular B Cell Response by Nera, K.‐P., Kyläniemi, M. K., Lassila, O.

“…Persistent humoral immunity depends on the follicular B cell response and on the generation of somatically mutated high‐affinity plasma cells and memory B…”
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BLIMP‐1 is insufficient to induce antibody secretion in the absence of IRF4 in DT40 cells by Budzyńska, P. M., Kyläniemi, M. K., Lassila, O., Nera, K.‐P., Alinikula, J.

“…Differentiation of B cells into antibody‐secreting cells (ASCs), plasmablasts and plasma cells is regulated by a network of transcription factors. Within this…”
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Web metadata: a matter of semantics by Lassila, O.

“…The sheer volume of information can make searching the Web frustrating. The paper considers how the Resource Description Framework, with its focus on…”
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IRF4 Deficiency Leads to Altered BCR Signalling Revealed by Enhanced PI3K Pathway, Decreased SHIP Expression and Defected Cytoskeletal Responses by Budzyńska, P. M., Niemelä, M., Sarapulov, A.V., Kyläniemi, M.K., Nera, K.‐P., Junttila, S., Laiho, A., Mattila, P.K., Alinikula, J., Lassila, O.

“…The graded expression of transcription factor interferon regulatory factor 4 (IRF4) regulates B cell development and is critical for plasma cell…”
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Pax5 – a Critical Inhibitor of Plasma Cell Fate by Nera, K.‐P., Lassila, O.

“…Paired box protein 5 (Pax5) is essential for early B cell commitment as well as for B cell development, and continuous expression of Pax5 is required…”
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What's on Users' Minds? Toward a Usable Smart Phone Security Model by Toninelli, A., Montanari, R., Lassila, O., Khushraj, D.

“…Smart phones pose new challenges to usable security. Current means of specifying security policies or preferences for resource sharing are either woefully…”
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Aiolos Controls Gene Conversion and Cell Death in DT40 B Cells by Narvi, E, Nera, K.-P, Terho, P, Mustonen, L, Granberg, J, Lassila, O

“…The Ikaros family transcription factor Aiolos is important for B cell function, since B cells of Aiolos-null mutant mice exhibit an activated phenotype,…”
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Chicken B‐Cell‐Activating Factor: Regulator of B‐Cell Survival in the Bursa of Fabricius by Koskela, K., Nieminen, P., Kohonen, P., Salminen, H., Lassila, O.

“…Previous studies on mammals have demonstrated that a tumour necrosis factor family member, B‐cell‐activating factor (BAFF) (BlyS, TALL‐1), is mainly produced…”
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Avian Model for B-Cell Immunology - New Genomes and Phylotranscriptomics by Kohonen, P, Nera, K.-P, Lassila, O

“…The purpose of this review is to discuss the use of chicken and other model organisms in the study of B-cell development and function as well as to highlight…”
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Non‐steroidal anti‐oestrogens inhibit the differentiation of synovial macrophages into dendritic cells by Komi, J., Möttönen, M., Luukkainen, R., Lassila, O.

“…Background. Dendritic cells (DC) have been suggested to play an important role in the pathogenesis of rheumatoid arthritis (RA). Agents that inhibit DC…”
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Single‐Cell Analysis of Ets‐1 Transcription Factor Expression during Lymphocyte Activation and Apoptosis by Koskela, K., Lassila, O.

“…The Ets‐1 proto‐oncogene is a prototype member of Ets family of transcription factors. It is preferentially expressed in lymphoid cells, where it is essential…”
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Interaction Between Borrelia burgdorferi and Immature Human Dendritic Cells by Suhonen, J., Komi, J., Soukka, J., Lassila, O., Viljanen, M. K.

“…Antigen uptake and the following maturation of dendritic cells (DCs) are pivotal to the initiation of specific antimicrobial immune responses. DCs also play an…”
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Cytokine Levels in Midtrimester Amniotic Fluid in Normal Pregnancy and in the Prediction of Pre‐eclampsia by Heikkinen, J., Möttönen, M., Pulkki, K., Lassila, O., Alanen, A.

“…Midtrimester amniotic fluid cytokines may reflect the function of the maternal immune system in the maternal–fetal interface and thus be predictive of…”
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Avian Helios and Evolution of the Ikaros Family by Kohonen, P., Nera, K.‐P., Lassila, O.

“…Helios (Znfn1a2) is an Ikaros‐related lymphoid regulatory protein with possible involvement in T‐cell development and function as well as in the early events…”
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Development of Early PCLP1‐Expressing Haematopoietic Cells within the Avian Dorsal Aorta by Suonpää, P., Kohonen, P., Koskela, K., Koskiniemi, H., Salminen‐Mankonen, H., Lassila, O.

“…The first haematopoietic stem cells (HSC) develop in the dorsal aorta as haematopoietic intra‐aortic clusters (HIAC). To evaluate the initial steps of…”
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