Search Results - "LASSEN, N. A"

Nitric oxide synthase inhibition and cerebrovascular regulation by Iadecola, C, Pelligrino, D A, Moskowitz, M A, Lassen, N A

“…There is increasing evidence that nitric oxide (NO) is an important molecular messenger involved in a wide variety of biological processes. Recent data suggest…”
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Benzodiazepine receptor quantification in vivo in humans using [11C]flumazenil and PET: application of the steady-state principle by Lassen, N A, Bartenstein, P A, Lammertsma, A A, Prevett, M C, Turton, D R, Luthra, S K, Osman, S, Bloomfield, P M, Jones, T, Patsalos, P N

“…Carbon-11-labeled flumazenil combined with positron emission tomography (PET) was used to measure the concentration (Bmax) of the benzodiazepine (Bz) receptor…”
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Ischemic stroke and incomplete infarction by GARCIA, J. H, LASSEN, N. A, WEILLER, C, SPERLING, B, NAKAGAWARA, J

“…The concept of selective vulnerability or selective loss o f individual neurons, with survival of glial and vascular elements as one of the consequences of a…”
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Heterogeneity of neocortical cerebral blood flow deficits in dementia of the Alzheimer type: a [99mTc]-d,l-HMPAO SPECT study by Waldemar, G, Bruhn, P, Kristensen, M, Johnsen, A, Paulson, O B, Lassen, N A

“…Regional cerebral blood flow (rCBF) was measured with high resolution brain dedicated single photon emission computer tomography (SPECT) and…”
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Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil by NAKAGAWARA, J, SPERLING, B, LASSEN, N. A

“…[123I]Iomazenil is a specific radioligand for the central benzodiazepine receptor that may be useful as an indicator of the intactness of cortical neurons…”
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Dynamic exercise enhances regional cerebral artery mean flow velocity by Linkis, P, Jørgensen, L G, Olesen, H L, Madsen, P L, Lassen, N A, Secher, N H

“…Dynamic exercise enhances regional cerebral artery mean flow velocity. J. Appl. Physiol. 78(1): 12-16, 1995.--Anterior (ACA) and middle (MCA) cerebral artery…”
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Cerebral O2 metabolism and cerebral blood flow in humans during deep and rapid-eye-movement sleep by Madsen, P L, Schmidt, J F, Wildschiødtz, G, Friberg, L, Holm, S, Vorstrup, S, Lassen, N A

“…It could be expected that the various stages of sleep were reflected in variation of the overall level of cerebral activity and thereby in the magnitude of…”
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Augmented hypoxic cerebral vasodilation in men during 5 days at 3,810 m altitude by Jensen, J B, Sperling, B, Severinghaus, J W, Lassen, N A

“…The fractional increase in cerebral blood flow (CBF) velocity (VCBF) from the control value with 5-min steps of isocapnic hypoxia and hyperoxic hypercapnia was…”
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Timing and topography of cerebral blood flow, aura, and headache during migraine attacks by Olesen, J, Friberg, L, Olsen, T S, Iversen, H K, Lassen, N A, Andersen, A R, Karle, A

“…Ten years of study has resulted in considerable but fragmented knowledge about regional cerebral blood flow in migraine with aura (classic migraine). In the…”
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Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique by Madsen, P L, Hasselbalch, S G, Hagemann, L P, Olsen, K S, Bülow, J, Holm, S, Wildschiødtz, G, Paulson, O B, Lassen, N A

“…Global cerebral blood flow (CBF), global cerebral metabolic rates for oxygen (CMRO2), and for glucose (CMRglc), and lactate efflux were measured during rest…”
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Middle cerebral artery blood velocity and cerebral blood flow and O2 uptake during dynamic exercise by Madsen, P L, Sperling, B K, Warming, T, Schmidt, J F, Secher, N H, Wildschiødtz, G, Holm, S, Lassen, N A

“…Results obtained by the 133Xe clearance method with external detectors and by transcranial Doppler sonography (TCD) suggest that dynamic exercise causes an…”
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A reappraisal of the relative merits of SPET and PET in the quantitation of neuroreceptors: the advantage of a longer half-life by Lassen, N A

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Activation-induced resetting of cerebral oxygen and glucose uptake in the rat by Madsen, P L, Linde, R, Hasselbalch, S G, Paulson, O B, Lassen, N A

“…In the clinical setting it has been shown that activation will increase cerebral glucose uptake in excess of cerebral oxygen uptake. To study this phenomenon…”
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Hyperfixation of HMPAO in subacute ischemic stroke leading to spuriously high estimates of cerebral blood flow by SPECT by Sperling, B, Lassen, N A

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Supplementary motor area and other cortical areas in organization of voluntary movements in man by Roland, P E, Larsen, B, Lassen, N A, Skinhøj, E

“…1. Previous studies in man have revealed a coupling between the regional cerebral blood flow (rCBF) and the regional cerebral metabolic rate for oxygen. In…”
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Average blood flow and oxygen uptake in the human brain during resting wakefulness: a critical appraisal of the Kety-Schmidt technique by Madsen, P L, Holm, S, Herning, M, Lassen, N A

“…The Kety-Schmidt technique can be regarded as the reference method for measurement of global average cerebral blood flow (average CBF) and global average…”
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The retention of [99mTc]-d,l-HM-PAO in the human brain after intracarotid bolus injection: a kinetic analysis by Lassen, N A, Andersen, A R, Friberg, L, Paulson, O B

“…[99mTc]-d,l-HM-PAO (HM-PAO) was injected rapidly into the internal carotid artery and its retention in the brain was recorded by external scintillation cameras…”
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Evaluation of the cerebral vasodilatory capacity by the acetazolamide test before EC-IC bypass surgery in patients with occlusion of the internal carotid artery by VORSTRUP, S, BRUN, B, LASSEN, N. A

“…Cerebral blood flow (CBF) was measured by xenon-133 inhalation tomography in 18 patients with cerebrovascular disease before and 4 months after…”
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The retention mechanism of technetium-99m-HM-PAO: intracellular reaction with glutathione by Neirinckx, R D, Burke, J F, Harrison, R C, Forster, A M, Andersen, A R, Lassen, N A

“…Preparations of d,l- and meso-hexamethylpropyleneamine oxime (HM-PAO) labeled with technetium-99m were added to rat brain homogenates diluted with phosphate…”
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Role of Extracellular and Intracellular Acidosis for Hypercapnia-Induced Inhibition of Tension of Isolated Rat Cerebral Arteries by Tian, Rong, Vogel, Pia, Lassen, Niels A, Mulvany, Michael J, Andreasen, Frederik, Aalkjaer, Christian

“…The importance of smooth muscle cell pHi and pHo for the hypercapnic vasodilation of rat cerebral arteries was evaluated in vitro.Vessel segments were mounted…”
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