Search Results - "LASOTA, JERZY"

Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis by Miettinen, Markku, Lasota, Jerzy

“…Gastrointestinal stromal tumors (GISTs) are specific, generally Kit (CD117)-positive, mesenchymal tumors of the gastrointestinal tract encompassing a majority…”
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Gastrointestinal stromal tumors: pathology and prognosis at different sites by Miettinen, Markku, Lasota, Jerzy

“…Gastrointestinal (GI) stromal tumors (GISTs) are the most common mesenchymal tumors specific to the GI tract, generally defined as KIT (CD117)-positive tumors…”
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Histopathology of gastrointestinal stromal tumor by Miettinen, Markku, Lasota, Jerzy

“…Gastrointestinal stromal tumor (GIST), generally driven by oncogenic KIT or PDGFRA mutations, is the most common mesenchymal tumor of the gastrointestinal (GI)…”
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Gastrointestinal Stromal Tumors by Miettinen, Markku, MD, Lasota, Jerzy, MD

“…Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gastrointestinal tract. Soon after GIST was recognized as a tumor driven…”
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Gastric schwannoma: a clinicopathologic study of 51 cases and critical review of the literature by Voltaggio, Lysandra, MD, Murray, Rebecca, MD, Lasota, Jerzy, MD, Miettinen, Markku, MD

“…Summary Schwannoma is a rare gastrointestinal mesenchymal tumor, as the vast majority of gastric mesenchymal tumors are gastrointestinal stromal tumors. In…”
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Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas by Inaguma, Shingo, Lasota, Jerzy, Wang, Zengfeng, Felisiak-Golabek, Anna, Ikeda, Hiroshi, Miettinen, Markku

“…The CD274 (PD-L1)/PDCD1 (PD-1) pathway is crucial for the modulation of immune responses and self-tolerance. Aberrantly expressed CD274 allows tumor cells to…”
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Primary malignant melanoma of esophagus: clinicopathologic characterization of 20 cases including molecular genetic profiling of 15 tumors by Lasota, Jerzy, Kowalik, Artur, Felisiak-Golabek, Anna, Zięba, Sebastian, Waloszczyk, Piotr, Masiuk, Marek, Wejman, Jaroslaw, Szumilo, Justyna, Miettinen, Markku

“…Primary malignant melanoma of esophagus is very rare, and its clinicopathologic and genetic features have not been extensively investigated. In this study, 20…”
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New fusion sarcomas: histopathology and clinical significance of selected entities by Miettinen, Markku, Felisiak-Golabek, Anna, Luiña Contreras, Alejandro, Glod, John, Kaplan, Rosandra N., Killian, Jonathan Keith, Lasota, Jerzy

“…Many sarcomas contain gene fusions that can be pathogenetic mechanisms and diagnostic markers. In this article we review selected fusion sarcomas and…”
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Gastrointestinal stromal tumors : definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis by MIETTINEN, Markku, LASOTA, Jerzy

“…Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract. They are defined here as KIT (CD117, stem…”
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Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor by Killian, J Keith, Kim, Su Young, Miettinen, Markku, Smith, Carly, Merino, Maria, Tsokos, Maria, Quezado, Martha, Smith, Jr, William I, Jahromi, Mona S, Xekouki, Paraskevi, Szarek, Eva, Walker, Robert L, Lasota, Jerzy, Raffeld, Mark, Klotzle, Brandy, Wang, Zengfeng, Jones, Laura, Zhu, Yuelin, Wang, Yonghong, Waterfall, Joshua J, O'Sullivan, Maureen J, Bibikova, Marina, Pacak, Karel, Stratakis, Constantine, Janeway, Katherine A, Schiffman, Joshua D, Fan, Jian-Bing, Helman, Lee, Meltzer, Paul S

“…Gastrointestinal stromal tumors (GIST) harbor driver mutations of signal transduction kinases such as KIT, or, alternatively, manifest loss-of-function defects…”
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Intranodal Palisaded Myofibroblastoma: Another Mesenchymal Neoplasm With CTNNB1 (β-catenin Gene) Mutations: Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of 18 Cases by Laskin, William B, Lasota, Jerzy P, Fetsch, John F, Felisiak-Golabek, Anna, Wang, Zeng-Feng, Miettinen, Markku

“…Intranodal palisaded myofibroblastoma is a benign, lymph node–based myofibroblastic tumor of unknown pathogenesis. We report the clinicopathologic,…”
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KIT and PDGFRA mutations in gastrointestinal stromal tumors (GISTs) by Lasota, Jerzy, Miettinen, Markku

“…Mutually exclusive KIT and PDGFRA mutations are central events in GIST pathogenesis, and their understanding is becoming increasingly important, because…”
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Expression of ALCAM (CD166) and PD-L1 (CD274) independently predicts shorter survival in malignant pleural mesothelioma by Inaguma, Shingo, Lasota, Jerzy, Wang, Zengfeng, Czapiewski, Piotr, Langfort, Renata, Rys, Janusz, Szpor, Joanna, Waloszczyk, Piotr, Okoń, Krzysztof, Biernat, Wojciech, Ikeda, Hiroshi, Schrump, David S., Hassan, Raffit, Miettinen, Markku

“…Diffuse malignant mesothelioma of the pleura is a highly aggressive tumor typically associated with short survival. ALCAM (CD166), a type I transmembrane…”
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Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review by Miettinen, Markku, Majidi, Mourad, Lasota, Jerzy

“…Gastrointestinal stromal tumor (GIST) is the designation for the specific c- kit expressing and Kit-signaling driven mesenchymal tumors, many of which have…”
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Expression of neural cell adhesion molecule L1 (CD171) in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in gastrointestinal stromal tumors by Inaguma, Shingo, Wang, Zengfeng, Lasota, Jerzy P, Miettinen, Markku M

“…The neural cell adhesion molecule L1 (CD171) is a multidomain type 1 membrane glycoprotein of the immunoglobulin superfamily important in the nervous system…”
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Frequency and clinicopathologic profile of PIK3CA mutant GISTs: molecular genetic study of 529 cases by Lasota, Jerzy, Felisiak-Golabek, Anna, Wasag, Bartosz, Kowalik, Artur, Zięba, Sebastian, Chłopek, Małgorzata, Wang, Zeng-Feng, Coates, Tiffany, Kopczynski, Janusz, Gozdz, Stanislaw, Sarlomo-Rikala, Maarit, Miettinen, Markku

“…Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors usually driven by the mutational activation of receptor tyrosine kinases, KIT, or PDGFRA…”
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MAGE-A is More Highly Expressed Than NY-ESO-1 in a Systematic Immunohistochemical Analysis of 3668 Cases by Kerkar, Sid P, Wang, Zeng-Feng, Lasota, Jerzy, Park, Tristen, Patel, Krishna, Groh, Eric, Rosenberg, Steven A, Miettinen, Markku M

“…Two cancer testis antigens, the New York esophageal squamous cell carcinoma-1 (NY-ESO-1) and the melanoma-antigen family A (MAGE-A), represent promising…”
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Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: A review by Miettinen, Markku, El-Rifai, Wa'El, H, Leslie, Lasota, Jerzy

“…This paper reviews data on the prognosis of gastrointestinal stromal tumors (GISTs). These tumors are specific KIT-expressing and KIT-signaling–driven…”
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Epithelioid variant of gastrointestinal stromal tumor harboring PDGFRA mutation and MLH1 gene alteration: A case report by Kobayashi, Mizuho, Inaguma, Shingo, Raffeld, Mark, Kato, Hiroyuki, Suzuki, Shugo, Wakasugi, Takehiro, Mitsui, Akira, Kuwabara, Yoshiyuki, Lasota, Jerzy, Ikeda, Hiroshi, Miettinen, Markku, Takahashi, Satoru

“…Gastrointestinal stromal tumors (GISTs) are the most important and common mesenchymal tumors of the gastrointestinal tract, especially in the stomach. GISTs…”
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Gastrointestinal Stromal Tumors Presenting as Omental Masses―A Clinicopathologic Analysis of 95 Cases by MIETTINEN, Markku, SOBIN, Leslie H, LASOTA, Jerzy

“…Gastrointestinal stromal tumors (GISTs), generally KIT-positive and KIT/PDGFRA mutation-driven mesenchymal neoplasms, most commonly originate from the stomach…”
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