Search Results - "LARSSON, O. M"

Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission by Schousboe, A., Sarup, A., Bak, L.K., Waagepetersen, H.S., Larsson, O.M.

“…The fine tuning of both glutamatergic and GABAergic neurotransmission is to a large extent dependent upon optimal function of astrocytic transport processes…”
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A Possible Role of Alanine for Ammonia Transfer Between Astrocytes and Glutamatergic Neurons by Waagepetersen, Helle S, Sonnewald, Ursula, Larsson, Orla M, Schousboe, Arne

“…The metabolism of [U‐13C]lactate (1 mM) in the presence of unlabeled glucose (2.5 mM) was investigated in glutamatergic cerebellar granule cells, cerebellar…”
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Radiative cooling of fullerene anions in a storage ring by ANDERSEN, J. U, GOTTRUP, C, HANSEN, K, HVELPLUND, P, LARSSON, M. O

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Selective Inhibitors of Glial GABA Uptake:  Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues by Falch, Erik, Perregaard, Jens, Frølund, Bente, Søkilde, Birgitte, Buur, Anders, Hansen, Lene M, Frydenvang, Karla, Brehm, Lotte, Bolvig, Tina, Larsson, Orla M, Sanchez, Connie, White, Harold S, Schousboe, Arne, Krogsgaard-Larsen, Povl

“…3-Methoxy-4,5,6,7-tetrahydro-1,2-benzisoxazol-4-one (20a), or the corresponding 3-ethoxy analogue (20b), and…”
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Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity by Bolvig, Tina, Larsson, Orla M, Pickering, Darryl S, Nelson, Nathan, Falch, Erik, Krogsgaard-Larsen, Povl, Schousboe, Arne

“…The inhibitory action of bicyclic isoxazole γ-aminobutyric acid (GABA) analogues and their 4,4-diphenyl-3-butenyl (DPB) substituted derivatives has been…”
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Kinetic characterization of inhibition of gamma-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine by Larsson, O M, Falch, E, Krogsgaard-Larsen, P, Schousboe, A

“…The effects of N-(4,4-diphenyl-3-butenyl) derivatives of nipecotic acid (SKF-89976-A and SKF-100844-A) and guvacine (SKF-100330-A) on neuronal and astroglial…”
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Characterization of L-glutamate uptake into and release from astrocytes and neurons cultured from different brain regions by Drejer, J, Larsson, O M, Schousboe, A

“…The uptake of L-glutamate was studied in astrocytes cultured from different brain areas of newborn rats as well as in two different cultures of neurons…”
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Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons by Gram, L, Larsson, O M, Johnsen, A H, Schousboe, A

“…Valproate (VPA) and vigabatrin (gamma-vinyl GABA, GVG) are two novel antiepileptic drugs with a presumed GABAergic mechanism of action. However, for VPA, this…”
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GABA uptake inhibitors: relevance to antiepileptic drug research by Krogsgaard-Larsen, P, Falch, E, Larsson, O M, Schousboe, A

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Fragmentation of fast positive and negative C60 ions in collisions with rare gas atoms by LARSEN, M. C, HVELPLUND, P, LARSSON, M. O, SHEN, H

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Kinetic characterization of GABA-transaminase from cultured neurons and astrocytes by LARSSON, O. M, SCHOUSBOE, A

“…The enzymatic mechanism and the kinetic parameters of GABA-transaminase extracted from cultured mouse cerebral cortex neurons and astrocytes were studied…”
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Ontogenetic development of glutamate metabolizing enzymes in cultured cerebellar granule cells and in cerebellum in vivo by DREJER, J, LARSSON, O. M, KVAMME, E, SVENNEBY, G, HERTZ, L, SCHOUSBOE, A

“…The ontogenetic development of the enzymes phosphate activated glutaminase (PAG), glutamate dehydrogenase (GLDH), glutamic-oxaloacetic-transaminase (GOT),…”
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Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes by Waagepetersen, Helle S., Sonnewald, Ursula, Larsson, Orla M., Schousboe, Arne

“…The metabolism of glucose and lactate was investigated in cultured mouse cerebellar astrocytes, a culture preparation consisting of a homogeneous population of…”
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Acetoacetate and glucose as lipid precursors and energy substrates in primary cultures of astrocytes and neurons from mouse cerebral cortex by Lopes-Cardozo, M, Larsson, O M, Schousboe, A

“…Primary cultures of astrocytes and neurons derived from neonatal and embryonic mouse cerebral cortex, respectively, were incubated with [3-14C]acetoacetate or…”
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Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes by Larsson, O M, Gram, L, Schousboe, I, Schousboe, A

“…A preferential effect of valproate on gamma-aminobutyric acid (GABA) in the nerve terminal compartment has been proposed. Gamma-vinyl GABA, an irreversible…”
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Trafficking between glia and neurons of TCA cycle intermediates and related metabolites by Schousboe, Arne, Westergaard, Niels, Waagepetersen, Helle S., Larsson, Orla M., Bakken, Inger J., Sonnewald, Ursula

“…Net synthesis of the neurotransmitter amino acids glutamate and GABA can take place either from glutamine or from α‐ketoglutarate or another tricarboxylic acid…”
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Characterization of uptake and release processes for D- and L-aspartate in primary cultures of astrocytes and cerebellar granule cells by Drejer, J, Larsson, O M, Schousboe, A

“…The uptake of L- and D-aspartate was studied in astrocytes cultured from prefrontal cortex and in granule cells cultured from cerebellum. A high affinity…”
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Experimental studies of the influence of vigabatrin on the GABA system by Gram, L, Larsson, OM, Johnsen, A, Schousboe, A

“…1. Studies of the influence of clinically relevant concentrations of vigabatrin on GABA‐transaminase and on the release of endogenous GABA were performed in…”
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Hyperfine structure of the lower configurations in Y II by fast ion beam-laser spectroscopy by Villemoes, P, Arnesen, A, Heijkenskjöld, F, Kastberg, A, Larsson, M O

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Radiative Cooling of C60 by Andersen, JU, Brink, C, Hvelplund, P, Larsson, MO, Nielsen, BB, Shen, H

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