Search Results - "LANTUEJOUL, Sylvie"
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Nivolumab or nivolumab plus ipilimumab in patients with relapsed malignant pleural mesothelioma (IFCT-1501 MAPS2): a multicentre, open-label, randomised, non-comparative, phase 2 trial
Published in The lancet oncology (01-02-2019)“…There is no recommended therapy for malignant pleural mesothelioma that has progressed after first-line pemetrexed and platinum-based chemotherapy. Disease…”
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The 2021 WHO Classification of Lung Tumors: Impact of Advances Since 2015
Published in Journal of thoracic oncology (01-03-2022)“…The 2021 WHO Classification of Thoracic Tumours was published earlier this year, with classification of lung tumors being one of the chapters. The principles…”
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Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma
Published in PloS one (10-10-2012)“…Splicing abnormalities frequently occur in cancer. A key role as splice site choice regulator is played by the members of the SR (Ser/Arg-rich) family of…”
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Routine molecular profiling of patients with advanced non-small-cell lung cancer: results of a 1-year nationwide programme of the French Cooperative Thoracic Intergroup (IFCT)
Published in The Lancet (British edition) (02-04-2016)“…Summary Background The molecular profiling of patients with advanced non-small-cell lung cancer (NSCLC) for known oncogenic drivers is recommended during…”
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PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee
Published in Journal of thoracic oncology (01-04-2020)“…The recent development of immune checkpoint inhibitors (ICIs) has led to promising advances in the treatment of patients with NSCLC and SCLC with advanced or…”
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The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker: A Perspective from the International Association for the Study of Lung Cancer Pathology Committee
Published in Journal of thoracic oncology (01-09-2020)“…Immune checkpoint inhibitor (ICI) therapies have revolutionized the management of patients with NSCLC and have led to unprecedented improvements in response…”
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Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non-Small-Cell Lung Cancer
Published in Journal of clinical oncology (10-04-2016)“…Tumor lymphocytic infiltration (TLI) has differing prognostic value among various cancers. The objective of this study was to assess the effect of TLI in lung…”
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Multicenter harmonization study for PD-L1 IHC testing in non-small-cell lung cancer
Published in Annals of oncology (01-04-2018)“…Various programed death ligand 1 (PD-L1) immunohistochemistry (IHC) assays have been developed and used in clinical trials in association with different drugs…”
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Subtype Classification of Lung Adenocarcinoma Predicts Benefit From Adjuvant Chemotherapy in Patients Undergoing Complete Resection
Published in Journal of clinical oncology (20-10-2015)“…The classification for invasive lung adenocarcinoma by the International Association for the Study of Lung Cancer, American Thoracic Society, European…”
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Predictive Biomarkers for Immunotherapy in Lung Cancer: Perspective From the International Association for the Study of Lung Cancer Pathology Committee
Published in Journal of thoracic oncology (01-12-2022)“…Immunotherapy including immune checkpoint inhibitors (ICIs) has become the backbone of treatment for most lung cancers with advanced or metastatic disease. In…”
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Nonsmall cell lung carcinoma: diagnostic difficulties in small biopsies and cytological specimens
Published in European respiratory review (01-09-2017)“…The pathological and molecular classification of lung cancer has become substantially more complex over the past decade. For diagnostic purposes on small…”
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The International Association for the Study of Lung Cancer Global Survey on Molecular Testing in Lung Cancer
Published in Journal of thoracic oncology (01-09-2020)“…Access to targeted therapies for lung cancer depends on the accurate identification of patients' biomarkers through molecular testing. The International…”
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SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas
Published in Nature genetics (01-10-2015)“…Francois Le Loarer, Franck Tirode and colleagues identify a new class of undifferentiated thoracic sarcomas characterized by inactivation of SMARCA4 , which…”
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The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group
Published in Lung cancer (Amsterdam, Netherlands) (01-04-2012)“…Highlights ► The diagnosis of lung cancer involves the identification and complete classification of malignancy. ► New therapeutic options require specific…”
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Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers
Published in Science translational medicine (22-05-2013)“…Activation of normally silent tissue-specific genes and the resulting cell "identity crisis" are the unexplored consequences of malignant epigenetic…”
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Rapid On-Site Evaluation of Endobronchial Ultrasound-Guided Transbronchial Needle Aspirations for the Diagnosis of Lung Cancer: A Perspective From Members of the Pulmonary Pathology Society
Published in Archives of pathology & laboratory medicine (1976) (01-02-2018)“…- Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a very useful tool in the field of diagnostic respiratory…”
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Pulmonary preneoplasia - sequential molecular carcinogenetic events
Published in Histopathology (01-01-2009)“…Bronchial and bronchioloalveolar carcinogenesis is a multicentric and multistep process, leading to a sequential accumulation of molecular and genetic…”
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Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study
Published in Journal of thoracic oncology (01-02-2012)“…In 2011, the French National Cancer Institute recommended ALK-fluorescence in situ hybridization (FISH) testing in all EGFR/KRAS-negative adenocarcinomas by…”
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Programmed Death Ligand-1 Immunohistochemistry--A New Challenge for Pathologists: A Perspective From Members of the Pulmonary Pathology Society
Published in Archives of pathology & laboratory medicine (1976) (01-04-2016)“…The binding of programmed death ligand-1 and ligand-2 (PD-L1 and PD-L2) to PD-1 blocks T-cell-mediated immune response to tumor. Antibodies that target…”
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