Search Results - "LANTHALER, Karin"

Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction Monitoring by Lawless, Craig, Holman, Stephen W., Brownridge, Philip, Lanthaler, Karin, Harman, Victoria M., Watkins, Rachel, Hammond, Dean E., Miller, Rebecca L., Sims, Paul F.G., Grant, Christopher M., Eyers, Claire E., Beynon, Robert J., Hubbard, Simon J.

“…Defining intracellular protein concentration is critical in molecular systems biology. Although strategies for determining relative protein changes are…”
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Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy by Brownridge, Philip, Holman, Stephen W., Gaskell, Simon J., Grant, Christopher M., Harman, Victoria M., Hubbard, Simon J., Lanthaler, Karin, Lawless, Craig, O'cualain, Ronan, Sims, Paul, Watkins, Rachel, Beynon, Robert J.

“…In this paper, we discuss the challenge of large‐scale quantification of a proteome, referring to our programme that aims to define the absolute quantity, in…”
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Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger by Guillemette, Thomas, van Peij, Noël N M E, Goosen, Theo, Lanthaler, Karin, Robson, Geoffrey D, van den Hondel, Cees A M J J, Stam, Hein, Archer, David B

“…Filamentous fungi such as Aspergillus niger have a high capacity secretory system and are therefore widely exploited for the industrial production of native…”
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Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast by Lanthaler, Karin, Bilsland, Elizabeth, Dobson, Paul D, Moss, Harry J, Pir, Pınar, Kell, Douglas B, Oliver, Stephen G

“…The uptake of drugs into cells has traditionally been considered to be predominantly via passive diffusion through the bilayer portion of the cell membrane…”
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Implications of the dominant role of transporters in drug uptake by cells by Dobson, Paul D, Lanthaler, Karin, Oliver, Stephen G, Kell, Douglas B

“…Drug entry into cells was previously believed to be via diffusion through the lipid bilayer of the cell membrane, with the contribution to uptake by…”
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Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae by Arvas, Mikko, Pakula, Tiina, Lanthaler, Karin, Saloheimo, Markku, Valkonen, Mari, Suortti, Tapani, Robson, Geoff, Penttilä, Merja

“…Secretion stress is caused by compromised folding, modification or transport of proteins in the secretory pathway. In fungi, induction of genes in response to…”
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Proteome Cold-Shock Response in the Extremely Acidophilic Archaeon, Cuniculiplasma divulgatum by Bargiela, Rafael, Lanthaler, Karin, Potter, Colin M, Ferrer, Manuel, Yakunin, Alexander F, Paizs, Bela, Golyshin, Peter N, Golyshina, Olga V

“…The archaeon is ubiquitous in acidic environments with low-to-moderate temperatures. However, molecular mechanisms underlying its ability to thrive at lower…”
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Transcriptome Analysis of Recombinant Protein Secretion by Aspergillus nidulans and the Unfolded-Protein Response In Vivo by SIMS, Andrew H, GENT, Manda E, LANTHALER, Karin, DUNN-COLEMAN, Nigel S, OLIVER, Stephen G, ROBSON, Geoffrey D

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Role of the bga1-Encoded Extracellular β-Galactosidase of Hypocrea jecorina in Cellulase Induction by Lactose by Seiboth, Bernhard, Hartl, Lukas, Salovuori, Noora, Lanthaler, Karin, Robson, Geoff D., Vehmaanperä, Jari, Penttilä, Merja E., Kubicek, Christian P.

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Absolute Quantification of the Glycolytic Pathway in Yeast by Carroll, Kathleen M., Simpson, Deborah M., Eyers, Claire E., Knight, Christopher G., Brownridge, Philip, Dunn, Warwick B., Winder, Catherine L., Lanthaler, Karin, Pir, Pınar, Malys, Naglis, Kell, Douglas B., Oliver, Stephen G., Gaskell, Simon J., Beynon, Robert J.

“…The availability of label-free data derived from yeast cells (based on the summed intensity of the three strongest, isoform-specific peptides) permitted a…”
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Absolute protein quantification of the yeast chaperome under conditions of heat shock by Mackenzie, Rebecca J., Lawless, Craig, Holman, Stephen W., Lanthaler, Karin, Beynon, Robert J., Grant, Chris M., Hubbard, Simon J., Eyers, Claire E.

“…Chaperones are fundamental to regulating the heat shock response, mediating protein recovery from thermal‐induced misfolding and aggregation. Using the QconCAT…”
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Absolute quantification of the glycolytic pathway in yeast: deployment of a complete QconCAT approach by Carroll, Kathleen M, Simpson, Deborah M, Eyers, Claire E, Knight, Christopher G, Brownridge, Philip, Dunn, Warwick B, Winder, Catherine L, Lanthaler, Karin, Pir, Pinar, Malys, Naglis, Kell, Douglas B, Oliver, Stephen G, Gaskell, Simon J, Beynon, Robert J

“…The availability of label-free data derived from yeast cells (based on the summed intensity of the three strongest, isoform-specific peptides) permitted a…”
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The use of continuous culture in systems biology investigations by Winder, Catherine L, Lanthaler, Karin

“…When acquiring data for systems biology studies, it is essential to perform the experiments in controlled and reproducible conditions. Advances in the fields…”
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Further developments towards a genome-scale metabolic model of yeast by Dobson, Paul D, Smallbone, Kieran, Jameson, Daniel, Simeonidis, Evangelos, Lanthaler, Karin, Pir, Pınar, Lu, Chuan, Swainston, Neil, Dunn, Warwick B, Fisher, Paul, Hull, Duncan, Brown, Marie, Oshota, Olusegun, Stanford, Natalie J, Kell, Douglas B, King, Ross D, Oliver, Stephen G, Stevens, Robert D, Mendes, Pedro

“…To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope…”
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Quantitative analysis of chaperone network throughput in budding yeast by Brownridge, Philip, Lawless, Craig, Payapilly, Aishwarya B., Lanthaler, Karin, Holman, Stephen W., Harman, Victoria M., Grant, Christopher M., Beynon, Robert J., Hubbard, Simon J.

“…The network of molecular chaperones mediates the folding and translocation of the many proteins encoded in the genome of eukaryotic organisms, as well as a…”
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Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy: Microbial Proteomics by BROWNRIDGE, Philip, HOLMAN, Stephen W, WATKINS, Rachel, BEYNON, Robert J, GASKELL, Simon J, GRANT, Christopher M, HARMAN, Victoria M, HUBBARD, Simon J, LANTHALER, Karin, LAWLESS, Craig, O'CUALAIN, Ronan, SIMS, Paul

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Circadian rhythmicity during prolonged chemostat cultivation of Neurospora crassa by Tralau, Tewes, Lanthaler, Karin, Robson, Geoff D., Crosthwaite, Susan K.

“…Following exposure to light and attainment of steady-state in the chemostat, Neurospora was grown in constant conditions of darkness at 25 °C for 6 days…”
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Role of the bga1-Encoded Extracellular {szligbeta}-Galactosidase of Hypocrea jecorina in Cellulase Induction by Lactose by Seiboth, Bernhard, Hartl, Lukas, Salovuori, Noora, Lanthaler, Karin, Robson, Geoff D, Vehmaanperä, Jari, Penttilä, Merja E, Kubicek, Christian P

“…Lactose is the only soluble and economically feasible carbon source for the production of cellulases or heterologous proteins regulated by cellulase expression…”
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