Search Results - "LANNOY, Vincent"
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A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia
Published in Science signaling (12-09-2017)“…GPR15 is an orphan G protein-coupled receptor (GPCR) that is found in lymphocytes. It functions as a co-receptor of simian immunodeficiency virus and HIV-2 and…”
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Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells
Published in The Journal of biological chemistry (20-09-2013)“…TLQP-21, a peptide derived from VGF (non-acronymic) by proteolytic processing, has been shown to modulate energy metabolism, differentiation, and cellular…”
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Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
Published in The Journal of biological chemistry (11-07-2003)“…Short chain fatty acids (SCFAs), including acetate, propionate, and butyrate, are produced at high concentration by bacteria in the gut and subsequently…”
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Pro- and Anti-Inflammatory Role of ChemR23 Signaling in Pollutant-Induced Inflammatory Lung Responses
Published in The Journal of immunology (1950) (15-02-2016)“…Inhalation of traffic-related particulate matter (e.g., diesel exhaust particles [DEPs]) is associated with acute inflammatory responses in the lung, and it…”
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Identification of a Novel Human ADP Receptor Coupled to Gi
Published in The Journal of biological chemistry (02-11-2001)“…We have cloned and expressed a novel human G-protein-coupled receptor closely related to the human P2Y12 receptor. It corresponds to the orphan receptor called…”
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The onecut transcription factor HNF6 is required for normal development of the biliary tract
Published in Development (Cambridge) (15-04-2002)“…During liver development, hepatoblasts differentiate into hepatocytes or biliary epithelial cells (BEC). The BEC delineate the intrahepatic and extrahepatic…”
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The role of ChemR23 in the induction and resolution of cigarette smoke-induced inflammation
Published in The Journal of immunology (1950) (01-05-2011)“…Chronic obstructive pulmonary disease is mainly triggered by cigarette smoke (CS) and progresses even after smoking cessation. CS induces an exaggerated influx…”
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Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7
Published in PloS one (28-02-2013)“…Recent studies have shown that heteromerization of the chemokine receptors CCR2, CCR5 and CXCR4 is associated to negative binding cooperativity. In the present…”
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Identification of Natural Ligands for the Orphan G Protein-coupled Receptors GPR7 and GPR8
Published in The Journal of biological chemistry (10-01-2003)“…GPR7 and GPR8 are two structurally related orphan G protein-coupled receptors, presenting high similarities with opioid and somatostatin receptors. Two…”
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Pharmacological characterization of human NPFF1 and NPFF2 receptors expressed in CHO cells by using NPY Y1 receptor antagonists
Published in European journal of pharmacology (01-09-2002)Get full text
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Hepatocyte Nuclear Factor 6, a Transcription Factor that Contains a Novel Type of Homeodomain and a Single cut Domain
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-1996)“…Tissue-specific transcription is regulated in part by cell type-restricted proteins that bind to defined sequences in target genes. The DNA-binding domain of…”
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OC-2, a Novel Mammalian Member of the ONECUT Class of Homeodomain Transcription Factors Whose Function in Liver Partially Overlaps with That of Hepatocyte Nuclear Factor-6
Published in The Journal of biological chemistry (29-01-1999)“…Transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6, are characterized by the presence of a single cut domain and…”
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Isoforms of Hepatocyte Nuclear Factor-6 Differ in DNA-binding Properties, Contain a Bifunctional Homeodomain, and Define the New ONECUT Class of Homeodomain Proteins
Published in The Journal of biological chemistry (29-05-1998)“…Hepatocyte nuclear factor-6 (HNF-6) contains a single cut domain and a homeodomain characterized by a phenylalanine at position 48 and a methionine at position…”
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Type I Protein C Deficiency Caused by Disruption of a Hepatocyte Nuclear Factor (HNF)-6/HNF-1 Binding Site in the Human Protein C Gene Promoter
Published in The Journal of biological chemistry (24-04-1998)“…Protein C is a vitamin K-dependent zymogen of a serine protease that inhibits blood coagulation by proteolytic inactivation of factors Va and VIIIa…”
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Transcriptional Stimulation by Hepatocyte Nuclear Factor-6
Published in The Journal of biological chemistry (21-07-2000)“…Transcription factors of the ONECUT class, whose prototype is HNF-6, contain a single cut domain and a divergent homeodomain characterized by a phenylalanine…”
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Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF)
Published in The Journal of biological chemistry (21-07-2000)“…Transcription factors of the ONECUT class, whose prototype is HNF-6, contain a single cut domain and a divergent homeodomain characterized by a phenylalanine…”
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The Transcription Factor Onecut-2 Controls the Microphthalmia-Associated Transcription Factor Gene
Published in Biochemical and biophysical research communications (03-08-2001)“…Microphthalmia-associated transcription factor (MITF) is essential for melanocyte differentiation. MITF mutations are associated with some cases of Waardenburg…”
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Pharmacological characterization of human NPFF(1) and NPFF(2) receptors expressed in CHO cells by using NPY Y(1) receptor antagonists
Published in European journal of pharmacology (20-09-2002)“…Neuropeptide FF (NPFF) belongs to an opioid-modulatory system including two precursors (pro-NPFF(A) and pro-NPFF(B)) and two G-protein coupled receptors…”
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Pharmacological characterization of human NPFF 1 and NPFF 2 receptors expressed in CHO cells by using NPY Y 1 receptor antagonists
Published in European journal of pharmacology (2002)“…Neuropeptide FF (NPFF) belongs to an opioid-modulatory system including two precursors (pro-NPFF A and pro-NPFF B) and two G-protein coupled receptors (NPFF 1…”
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