Search Results - "LANKOFF, Anna"
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Targeted Radionuclide Therapy of Prostate Cancer-From Basic Research to Clinical Perspectives
Published in Molecules (Basel, Switzerland) (10-04-2020)“…Prostate cancer is the most commonly diagnosed malignancy in men and the second leading cause of cancer-related deaths in Western civilization. Although…”
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Nanoparticle-Based Radioconjugates for Targeted Imaging and Therapy of Prostate Cancer
Published in Molecules (Basel, Switzerland) (16-05-2023)“…Prostate cancer is the second most frequent malignancy in men worldwide and the fifth leading cause of death by cancer. Although most patients initially…”
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Hypothermia differentially modulates the formation and decay of NBS1, γH2AX and 53BP1 foci in U2OS cells exposed to gamma radiation
Published in Scientific reports (07-04-2022)“…In studies on the mechanism of DNA damage response where ionizing radiation is used as the DNA damaging agent, cells are often exposed to ionizing radiation on…”
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The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells
Published in Toxicology letters (05-02-2012)“…► Ag and TiO 2 nanoparticles are efficiently taken up by A549, HepG2 and THP1 cells. ► Ag and TiO 2 nanoparticles decrease metabolic activation and increase…”
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Design and Evaluation of 223Ra-Labeled and Anti-PSMA Targeted NaA Nanozeolites for Prostate Cancer Therapy–Part I
Published in Materials (02-09-2020)“…Prostate cancer is the second most frequent malignancy in men worldwide. Unfortunately, current therapies often lead to the onset of metastatic…”
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Design and Evaluation of 223Ra-Labeled and Anti-PSMA Targeted NaA Nanozeolites for Prostate Cancer Therapy—Part II. Toxicity, Pharmacokinetics and Biodistribution
Published in International journal of molecular sciences (27-05-2021)“…Metastatic castration-resistant prostate cancer (mCRPC) is a progressive and incurable disease with poor prognosis for patients. Despite introduction of novel…”
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Coralyne Radiosensitizes A549 Cells by Upregulation of CDKN1A Expression to Attenuate Radiation Induced G2/M Block of the Cell Cycle
Published in International journal of molecular sciences (28-05-2021)“…Coralyne is a synthetic analog of berberine related to protoberberine-isoquinoline alkaloids. Isoquinoline derivatives and analogs are renowned as potent…”
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Hypothermia modulates the DNA damage response to ionizing radiation in human peripheral blood lymphocytes
Published in International journal of radiation biology (16-04-2018)“…Low temperature at exposure has been shown to act in a radioprotective manner at the level of cytogenetic damage. It was suggested to be due to an effective…”
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No evidence of the long-term in vitro toxicity of Aeroxide P25 TiO2 nanoparticles in three mammalian cell lines despite the initial reduction of cellular mitochondrial activity
Published in Nukleonika (01-03-2024)“…We studied the effects of Aeroxide P25 titanium dioxide nanoparticles (TiO2 NPs) with a diameter of 21 nm on induction of DNA damage and long-term survival of…”
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A cross-platform public domain PC image-analysis program for the comet assay
Published in Mutation research (10-01-2003)“…The single-cell gel electrophoresis, also known as the comet assay, has gained wide-spread popularity as a simple and reliable method to measure genotoxic and…”
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Dietary Intervention with Blackcurrant Pomace Protects Rats from Testicular Oxidative Stress Induced by Exposition to Biodiesel Exhaust
Published in Antioxidants (01-08-2022)“…The exposure to diesel exhaust emissions (DEE) contributes to negative health outcomes and premature mortality. At the same time, the health effects of the…”
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Cisplatin Reduces the Frequencies of Radiotherapy-Induced Micronuclei in Peripheral Blood Lymphocytes of Patients with Gynaecological Cancer: Possible Implications for the Risk of Second Malignant Neoplasms
Published in Cells (Basel, Switzerland) (09-10-2021)“…Gynaecologic cancers are common among women and treatment includes surgery, radiotherapy or chemotherapy, where the last two methods induce DNA damage in…”
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Individual variations in the micronucleus assay for biological dosimetry after high dose exposure
Published in Mutation research (30-08-2013)“…The micronucleus assay is widely used as a biological dosimeter. Due to an inhibitory effect of radiation on cell proliferation the assay yields satisfactory…”
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The uptake kinetics and immunotoxic effects of microcystin-LR in human and chicken peripheral blood lymphocytes in vitro
Published in Toxicology (Amsterdam) (01-11-2004)“…Microcystin-LR is a cyanobacterial heptapeptide that presents acute and chronic hazards to animal and human health. We investigated the influence of this toxin…”
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Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin
Published in Toxicology in vitro (01-09-2007)“…Neutropenia is the primary dose-limiting effect of etoposide toxicity resulting in a decreased efficiency of cancer treatment. Hence, the protection of…”
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Effect of microcystin-LR and cyanobacterial extract from polish reservoir of drinking water on cell cycle progression, mitotic spindle, and apoptosis in CHO-K1 cells
Published in Toxicology and applied pharmacology (15-06-2003)“…Microcystin-LR is a cyanobacterial toxin possessing a potent tumor-promoting activity mediated through inhibition of protein phosphatases PP1 and PP2A. Because…”
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Protective effect of melatonin against nodularin-induced oxidative stress in mouse liver
Published in Archives of toxicology (01-04-2002)“…Nodularin is a hepatotoxin from a cyanobacterium, Nodularia spumigena, that inhibits protein phosphatases 1 and 2 and posseses tumor-promoting activity. The…”
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Fullerenol C60(OH)36 protects human erythrocyte membrane against high-energy electrons
Published in Biochimica et biophysica acta. Biomembranes (01-08-2018)“…Fullerenols (polyhydroxylated fullerene C60) are nanomaterial with potentially broad applicability in biomedical sciences with high antioxidant ability, thus,…”
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Fullerenol C 60 (OH) 36 protects human erythrocyte membrane against high-energy electrons
Published in Biochimica et biophysica acta. Biomembranes (01-08-2018)“…Fullerenols (polyhydroxylated fullerene C ) are nanomaterial with potentially broad applicability in biomedical sciences with high antioxidant ability, thus,…”
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Silver nanoparticles -- allies or adversaries?
Published in Annals of Agricultural and Environmental Medicine (2013)“…Nanoparticles (NP) are structures with at least one dimension of less than 100 nanometers (nm) and unique properties. Silver nanoparticles (AgNP), due to their…”
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