Search Results - "LANGMAN, Michael J. S"

Sudden death in patients receiving drugs tending to prolong the QT interval by Jolly, Kate, Gammage, Michael D., Cheng, Kar Keung, Bradburn, Peter, Banting, Miriam V., Langman, Michael J. S.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Drugs slowing electocardiographic QT conduction can cause tachyarrhythmias, torsades de pointes (TdP) and cardiac…”
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Antihypertensive medication and the risk of acute pancreatitis: The European case-control study on drug-induced acute pancreatitis (EDIP) by Eland, Ingo A., Sundström, Anders, Velo, Giancarlo P., Andersen, Morten, Sturkenboom, Miriam C. J. M., Langman, Michael J. S., Stricker, Bruno H. CH, Wiholm, Beje, FOR THE EDIP STUDY GROUP OF THE EUROPEAN PHARMACOVIGILANCE RESEARCH GROUP

“…Objective. Angiotensin-converting enzyme (ACE) inhibitors and diuretics have been associated with acute pancreatitis. We quantified the risk of acute…”
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Adverse effects of conventional non-steroidal anti-inflammatory drugs on the upper gastrointestinal tract by Langman, Michael J. S.

“…This article reviews the clinical and epidemiological features of conventional non‐steroidal anti‐inflammatory drug (NSAID) related peptic ulcer complications,…”
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Psychotropic medication: curing illness or creating problems? by Jolly, Kate, Langman, Michael J S

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NSAIDs and gastrointestinal cancer prevention by JOLLY, Kate, CHENG, Kar K, LANGMAN, Michael J. S

“…Numerous studies report the relationship between aspirin and other nonsteroidal anti-inflammatories (NSAIDs) and cancer incidence, in particular for colorectal…”
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Loss of Estrogen Inactivation in Colonic Cancer by English, Mark A, Kane, Kate F, Cruickshank, Neil, Langman, Michael J. S, Stewart, Paul M, Hewison, Martin

“…Age and sex differences in the incidence of colonic cancer, together with epidemiological data on patients taking hormone replacement therapy, suggest the…”
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Controversies in COX-2 selective inhibition by SIMON, Lee S, SMOLEN, Josef S, DOUGADOS, Maxime, DUBOIS, Raymond N, FITZGERALD, Garret A, FRISHMAN, W, GARCIA RODRIGUEZ, Luis A, HOCHBERG, Marc C, KALDEN, Joachim R, LAINE, Loren, LANGMAN, Michael J. S, PRESCOTT, Stephen M, ABRAMSON, Steven B, VAN DE PUTTE, Leo B. A, WHELTON, Andrew, WHITE, William B, WILLIAMS, Gordon H, APPEL, Gerald, BOMBARDIER, Claire, BRATER, D. Craig, BREEDVELD, Ferdinand C, BRUNE, Kay, BURMESTER, Gerd R, CROFFORD, Leslie J

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Heparin therapy for ulcerative colitis? Effects and mechanisms by MICHELL, Nicholas P, LALOR, Patricia, LANGMAN, Michael J. S

“…Despite intensive medical treatment with steroids and immunosuppressants, acute colitis is still associated with a colectomy rate of up to 15%. Following the…”
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Targets of 17β-oestradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? by YAN QIU, LANGMAN, Michael J. S, EGGO, Margaret C

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Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205 by Lewis, Aurélia E., Susarla, Radhika, Wong, Benjamin C.Y., Langman, Michael J.S., Eggo, Margaret C.

“…Activation of protein kinase C δ (PKCδ) is believed to be pro-apoptotic. PKCδ is reported to be reduced in colon cancers. Using a colon cancer cell line, COLO…”
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Smoking And Ulcerative Colitis [With Reply] by Kennedy, H. G., Amery, K. V., Logan, R., Langman, Michael J. S.

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Protein kinase C inhibition induces DNA fragmentation in COLO 205 cells which is blocked by cysteine protease inhibition but not mediated through caspase-3 by Lewis, Aurélia E, Wong, Benjamin C.Y, Langman, Michael J.S, Eggo, Margaret C

“…Enhancing apoptosis to remove abnormal cells has potential in reversing cancerous processes. Caspase-3 activation generally accompanies apoptosis and its…”
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Targets of 17beta-oestradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? by Qiu, Y, Langman, MJ, Eggo, MC

“…Epidemiological studies show a strong link between postmenopausal hormone replacement therapy and decreased incidence of colorectal cancer. The colon cancer…”
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ABC of colorectal cancer: Epidemiology by Boyle, Peter, Langman, Michael J S

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Expression of oestrogen receptor and oestrogen-inducible genes ps2 and erd5 in large bowel mucosa and cancer by Singh, Sukhdev, Poulsom, Richard, Hanby, Andrew M., Rogers, Len A., Wright, Nicholas A., Sheppard, Michael C., Langman, Michael J. S.

“…Since there is a preponderance of large bowel cancer in males, both in humans and in experimental models, and hormone replacement therapy is protective, a role…”
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Smoking And Crohn's Disease by Somerville, Kevin W., Logan, Richard F. A., Edmond, Margaret, Langman, Michael J. S.

“…In a case-control study 82 patients with Crohn's disease and matched controls drawn from general practice lists were questioned about their smoking habits…”
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Safety of acid-suppressing drugs by SMALLWOOD, R. A, BERLIN, R. G, CASTAGNOLI, N, FESTEN, H. P. M, HAWKEY, C. J, LAM, S. K, LANGMAN, M. J. S, LUNDBORG, P, PARKINSON, A

“…There is an extensive literature on the adverse effects of drugs that inhibit gastric acid secretion. This study presents a critical examination of…”
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Smoking And Ulcerative Colitis by Logan, Richard F. A., Edmond, Margaret, Somerville, Kevin W., Langman, Michael J. S.

“…In a case-control study of smoking and ulcerative colitis patients with the disease were much less likely to smoke than community controls matched for age and…”
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Testing the efficacy of antisecretory drugs in patients with haematemesis and melaena by Langman, M J

“…Despite the logical expectation of effectiveness, and wide use, of antisecretory drugs in the initial management of patients with hematemesis and melaena,…”
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Smoking and ulcerative colitis: 2 by Kennedy, H G

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