Search Results - "LANGFORD, Dianne"

Considerations for the use of SH-SY5Y neuroblastoma cells in neurobiology by Kovalevich, Jane, Langford, Dianne

“…The use of primary mammalian neurons derived from embryonic central nervous system tissue is limited by the fact that once terminally differentiated into…”
Get more information

Mitochondrial quality control in cardiac cells: Mechanisms and role in cardiac cell injury and disease by Tahrir, Farzaneh G., Langford, Dianne, Amini, Shohreh, Mohseni Ahooyi, Taha, Khalili, Kamel

“…Mitochondria play an important role in maintaining cardiac homeostasis by supplying the major energy required for cardiac excitation–contraction coupling as…”
Get full text

HIV and antiretroviral therapy in the brain: neuronal injury and repair by Ellis, Ronald, Langford, Dianne, Masliah, Eliezer

“…Approximately 40 million people worldwide are infected with human immunodeficiency virus (HIV). Despite HIV's known propensity to infect the CNS and cause…”
Get full text

Immediate Removal From Activity After Sport-Related Concussion Is Associated With Shorter Clinical Recovery and Less Severe Symptoms in Collegiate Student-Athletes by Asken, Breton M., Bauer, Russell M., Guskiewicz, Kevin M., McCrea, Michael A., Schmidt, Julianne D., Giza, Christopher C., Snyder, Aliyah R., Houck, Zachary M., Kontos, Anthony P., McAllister, Thomas W., Broglio, Steven P., Clugston, James R., Anderson, Scott, Bazarian, Jeff, Brooks, Alison, Buckley, Thomas, Chrisman, Sara, Collins, Michael, DiFiori, John, Duma, Stefan, Dykhuizen, Brian, Eckner, James T., Feigenbaum, Luis, Hoy, April, Kelly, Louise, Langford, T. Dianne, Lintner, Laura, McGinty, Gerald, Mihalik, Jason, Miles, Christopher, Ortega, Justus, Port, Nicholas, Putukian, Margot, Rowson, Steve, Svoboda, Steven

“…Background: Timely removal from activity after concussion symptoms remains problematic despite heightened awareness. Previous studies indicated potential…”
Get full text

Cocaine-mediated activation of microglia and microglial MeCP2 and BDNF production by Cotto, Bianca, Li, Hongbo, Tuma, Ronald F., Ward, Sara Jane, Langford, Dianne

“…The molecular substrates underlying cocaine reinforcement and addiction have been studied for decades, with a primary focus on signaling molecules involved in…”
Get full text

Antibodies from Multiple Sclerosis Brain Identified Epstein-Barr Virus Nuclear Antigen 1 & 2 Epitopes which Are Recognized by Oligoclonal Bands by Wang, Zhe, Kennedy, Peter GE, Dupree, Cecily, Wang, Min, Lee, Catherin, Pointon, Tiffany, Langford, T. Dianne, Graner, Michael W, Yu, Xiaoli

“…Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS), the etiology of which is poorly understood. The…”
Get full text

Astrocytes, HIV and the Glymphatic System: A Disease of Disrupted Waste Management? by Tice, Caitlin, McDevitt, Jane, Langford, Dianne

“…The discovery of the glial-lymphatic or glymphatic fluid clearance pathway in the rodent brain led researchers to search for a parallel system in humans and to…”
Get full text

SUMOylation and Viral Infections of the Brain by Imbert, Fergan, Leavitt, Gabrielle, Langford, Dianne

“…The small ubiquitin-like modifier (SUMO) system regulates numerous biological processes, including protein localization, stability and/or activity,…”
Get full text

Role of hexokinase-1 in the survival of HIV-1-infected macrophages by Sen, Satarupa, Kaminiski, Rafal, Deshmane, Satish, Langford, Dianne, Khalili, Kamel, Amini, Shohreh, Datta, Prasun K

“…Viruses have developed various strategies to protect infected cells from apoptosis. HIV-1 infected macrophages are long-lived and considered reservoirs for…”
Get full text

Concussions in young adult athletes: No effect on cerebral white matter by Hoffman, Linda J, Mis, Rachel E, Brough, Caroline, Ramirez, Servio, Langford, Dianne, Giovannetti, Tania, Olson, Ingrid R

“…The media's recent focus on possible negative health outcomes following sports- related concussion has increased awareness as well as anxiety among parents and…”
Get full text

Editorial: Advances in Understanding NeuroHIV Associated Changes in Neuroimmune Communication in the Combined Anti-retroviral Therapy (cART) Era by Gaskill, Peter J, Fields, Jerel Adam, Langford, Dianne T, Stauch, Kelly L, Williams, Dionna W

Get full text

Citrate shuttling in astrocytes is required for processing cocaine-induced neuron-derived excess peroxidated fatty acids by Natarajaseenivasan, Kalimuthusamy, Garcia, Alvaro, Velusamy, Prema, Shanmughapriya, Santhanam, Langford, Dianne

“…Disturbances in lipid metabolism in the CNS contribute to neurodegeneration and cognitive impairments. Through tight metabolic coupling, astrocytes provide…”
Get full text

PINCH: More than just an adaptor protein in cellular response by Kovalevich, Jane, Tracy, Brittany, Langford, Dianne

“…Particularly interesting new cysteine‐histidine‐rich protein (PINCH) is a LIM‐domain‐only adaptor protein involved in protein recruitment, subsequent assembly…”
Get full text

Sex Differences in Neck Strength Force and Activation Patterns in Collegiate Contact Sport by Gallo, Caitlin A, Desrochers, Gabrielle N, Morris, Garett J, Rumney, Chad D, Sandell, Sydney J, McDevitt, Jane K, Langford, Dianne, Rosene, John M

“…The purpose of this study was to assess changes in cervical musculature throughout contact-heavy collegiate ice hockey practices during a regular season of…”
Get full text

Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons by Natarajaseenivasan, Kalimuthusamy, Shanmughapriya, Santhanam, Velusamy, Prema, Sayre, Matthew, Garcia, Alvaro, Gomez, Nestor Mas, Langford, Dianne

“…Diseases and disorders with a chronic neuroinflammatory component are often linked with changes in brain metabolism. Among neurodegenerative disorders, people…”
Get full text

HIV-1 Tat and Cocaine Impair Survival of Cultured Primary Neuronal Cells via a Mitochondrial Pathway by De Simone, Francesca Isabella, Darbinian, Nune, Amini, Shohreh, Muniswamy, Madesh, White, Martyn K., Elrod, John W., Datta, Prasun K., Langford, Dianne, Khalili, Kamel

“…Addictive stimulant drugs, such as cocaine, are known to increase the risk of exposure to HIV-1 infection and hence predispose towards the development of AIDS…”
Get full text

Big Data in traumatic brain injury; promise and challenges by Agoston, Denes V, Langford, Dianne

“…Traumatic brain injury (TBI) is a spectrum disease of overwhelming complexity, the research of which generates enormous amounts of structured, semi-structured…”
Get full text

Cannabinoids Reduce Extracellular Vesicle Release from HIV-1 Infected Myeloid Cells and Inhibit Viral Transcription by DeMarino, Catherine, Cowen, Maria, Khatkar, Pooja, Cotto, Bianca, Branscome, Heather, Kim, Yuriy, Sharif, Sarah Al, Agbottah, Emmanuel T, Zhou, Weidong, Costiniuk, Cecilia T, Jenabian, Mohammad-Ali, Gelber, Cohava, Liotta, Lance A, Langford, Dianne, Kashanchi, Fatah

“…Of the 37.9 million individuals infected with human immunodeficiency virus type 1 (HIV-1), approximately 50% exhibit HIV-associated neurocognitive disorders…”
Get full text

Effects of purposeful soccer heading on circulating small extracellular vesicle concentration and cargo by Muñoz, Eric R., Caccese, Jaclyn B., Wilson, Brittany E., Shuler, Kyle T., Santos, Fernando V., Cabán, Carolina T., Jeka, John J., Langford, Dianne, Hudson, Matthew B.

“…•The present study is the first to identify and characterize a previously unknown microRNA, miR-7844-5p, that may be involved in cellular signaling cascades…”
Get full text

PINCH in the cellular stress response to tau-hyperphosphorylation by Ozdemir, Ahmet Yunus, Rom, Inna, Kovalevich, Jane, Yen, William, Adiga, Radhika, Dave, Rajnish S, Langford, Dianne

“…Particularly interesting new cysteine- histidine- rich protein (PINCH) is an adaptor protein that our data have shown is required for neurite extension under…”
Get full text