Search Results - "LANDO, Malin"
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A new and improved host-independent plasmid system for RK2-based conjugal transfer
Published in PloS one (03-03-2014)“…Bacterial conjugation is a process that is mediated either by a direct cell-to-cell junction or by formation of a bridge between the cells. It is often used to…”
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2
Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI
Published in Cancer research (Chicago, Ill.) (15-10-2012)“…Knowledge of the molecular background of functional magnetic resonance (MR) images is required to fully exploit their potential in cancer management. We…”
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Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Published in Clinical cancer research (15-08-2016)“…A 31-gene expression signature reflected in dynamic contrast enhanced (DCE)-MR images and correlated with hypoxia-related aggressiveness in cervical cancer was…”
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4
Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer
Published in Nature communications (2013)“…Although human papillomavirus was identified as an aetiological factor in cervical cancer, the key human gene drivers of this disease remain unknown. Here we…”
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Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
Published in The Journal of pathology (01-05-2013)“…The pathogenetic role, including its target genes, of the recurrent 3p12–p14 loss in cervical cancer has remained unclear. To determine the onset of the event…”
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Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer
Published in PLoS genetics (01-11-2009)“…Integrative analysis of gene dosage, expression, and ontology (GO) data was performed to discover driver genes in the carcinogenesis and chemoradioresistance…”
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7
Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer
Published in Epigenetics (03-10-2015)“…Loss of 3p11-p14 is a frequent event in epithelial cancer and a candidate prognostic biomarker in cervical cancer. In addition to loss, promoter methylation…”
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8
Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence
Published in Oncotarget (12-07-2016)“…Cervical cancer and a subset of anogenital and head-and-neck carcinomas are caused by high-risk types of the human papillomavirus (hrHPV). During hrHPV-induced…”
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Abstract 807: Eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Genetic gains and losses, i.e. gene dosage alterations, influence gene expressions and thereby promote tumor development and progression…”
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Membranous Expression of Ectodomain Isoforms of the Epidermal Growth Factor Receptor Predicts Outcome after Chemoradiotherapy of Lymph Node―Negative Cervical Cancer
Published in Clinical cancer research (15-08-2011)“…We compared the prognostic significance of ectodomain isoforms of the epidermal growth factor receptor (EGFR), which lack the tyrosine kinase (TK) domain, with…”
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11
Hypoxia-induced alterations of G2 checkpoint regulators
Published in Molecular oncology (01-05-2016)“…Hypoxia promotes an aggressive tumor phenotype with increased genomic instability, partially due to downregulation of DNA repair pathways. However, genome…”
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Phosphorylation of EGFR measured with in situ proximity ligation assay: Relationship to EGFR protein level and gene dosage in cervical cancer
Published in Radiotherapy and oncology (01-10-2011)“…Abstract Purpose We have applied the sensitive and specific in situ proximity ligation assay (PLA) to characterize Tyr1068 phosphorylation of the epidermal…”
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13
A New and Improved Host-Independent Plasmid System for RK2-Based Conjugal Transfer: e90372
Published in PloS one (01-03-2014)“…Bacterial conjugation is a process that is mediated either by a direct cell-to-cell junction or by formation of a bridge between the cells. It is often used to…”
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14
Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical Cancer: e1000719
Published in PLoS genetics (01-11-2009)“…Integrative analysis of gene dosage, expression, and ontology (GO) data was performed to discover driver genes in the carcinogenesis and chemoradioresistance…”
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15
GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
Published in Genome biology (23-05-2008)“…Absolute tumor DNA copy numbers can currently be achieved only on a single gene basis by using fluorescence in situ hybridization (FISH). We present GeneCount,…”
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