Search Results - "LAMPRECHT, Sergio A"

Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms by Lamprecht, Sergio A, Lipkin, Martin

“…Recent findings have indicated that dietary calcium, vitamin D and folate can modulate and inhibit colon carcinogenesis. Supporting evidence has been obtained…”
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Cox-2 expression, PGE₂ and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice by Gravaghi, Claudia, La Perle, Krista M.D, Ogrodwski, Paul, Kang, Jing X, Quimby, Fred, Lipkin, Martin, Lamprecht, Sergio A

“…There is great interest in the role of polyunsaturated fatty acids (PUFAs) in promoting (n-6 class) or inhibiting (n-3 class) inflammation. Mammalian cells are…”
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Dietary factors in human colorectal cancer by Lipkin, M, Reddy, B, Newmark, H, Lamprecht, S.A

“…Colorectal cancer is a significant cause of mortality in Western societies. The progression of the disease from normal colonic epithelium to the acquisition of…”
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Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon by Yang, Kan, Lamprecht, Sergio A., Liu, Yanhui, Shinozaki, Hiroharu, Fan, Kunhua, Leung, Denis, Newmark, Harold, Steele, Vernon E., Kelloff, Gary J., Lipkin, Martin

“…In this study we investigated the chemopreventive effects of quercetin and rutin when added to standard AIN-76A diet and fed to normal and azoxymethane…”
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Cellular Mechanisms of Calcium and Vitamin D in the Inhibition of Colorectal Carcinogenesis by LAMPRECHT, SERGIO A., LIPKIN, MARTIN

“…Convincing evidence is available showing that dietary calcium and vitamin D impede the development of colonic carcinogenesis. The major cellular modes of…”
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Cox-2 expression, PGE(2) and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice by Gravaghi, Claudia, La Perle, Krista M D, Ogrodwski, Paul, Kang, Jing X, Quimby, Fred, Lipkin, Martin, Lamprecht, Sergio A

“…There is great interest in the role of polyunsaturated fatty acids (PUFAs) in promoting (n-6 class) or inhibiting (n-3 class) inflammation. Mammalian cells are…”
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Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice by Yang, Kan, Lamprecht, Sergio A, Shinozaki, Hiroharu, Fan, Kunhua, Yang, Wancai, Newmark, Harold L, Kopelovich, Levy, Edelmann, Winfried, Jin, Bo, Gravaghi, Claudia, Augenlicht, Leonard, Kucherlapati, Raju, Lipkin, Martin

“…Both epidemiological and experimental findings have indicated that components of Western diets influence colonic tumorigenesis. Among dietary constituents,…”
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Migrating colonic crypt epithelial cells: primary targets for transformation by Lamprecht, Sergio A., Lipkin, Martin

“…It is widely believed that stem cells are the relevant target cells for colonic cell transformation. Evidence is presented that a proliferative transit…”
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Mechanisms of action of vitamin D: recent findings and new questions by Lipkin, Martin, Lamprecht, Sergio A

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Mouse Models of Gastrointestinal Tumorigenesis for Dietary Cancer Prevention Studies by Lamprecht, Sergio A, Lipkin, Martin

“…Mouse models have been generated to help identify dietary components that are protective against gastrointestinal tumorigenesis. Some of the models are…”
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Peroxisome proliferator‐activated receptor γ agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/− double mutant mice by Yang, Kan, Fan, Kun‐Hua, Lamprecht, Sergio A., Edelmann, Winfried, Kopelovich, Levy, Kucherlapati, Raju, Lipkin, Martin

“…The role of the nuclear peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) in colon tumorigenesis remains controversial. Notwithstanding evidence that…”
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Apoptosis (programmed cell death) in colonic cells : from normal to transformed stage by LIFSHITZ, Sarit, LAMPRECHT, Sergio A, BENHARROCH, Daniel, PRINSLOO, Isebrand, POLAK-CHARCON, Sylvie, SCHWARTZ, Betty

“…We determined apoptosis in whole rat colonic tissue and in isolated colonocytes from the various rat crypt regions in preneoplastic stages up to frank…”
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Cox-2 expression, PGE sub(2 and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice) by Gravaghi, Claudia, La Perle, Krista MD, Ogrodwski, Paul, Kang, Jing X, Quimby, Fred, Lipkin, Martin, Lamprecht, Sergio A

“…There is great interest in the role of polyunsaturated fatty acids (PUFAs) in promoting (n-6 class) or inhibiting (n-3 class) inflammation. Mammalian cells are…”
Get full text

Cox-2 expression, PGE 2 and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice by Gravaghi, Claudia, La Perle, Krista M.D., Ogrodwski, Paul, Kang, Jing X., Quimby, Fred, Lipkin, Martin, Lamprecht, Sergio A.

“…There is great interest in the role of polyunsaturated fatty acids (PUFAs) in promoting ( n-6 class) or inhibiting ( n-3 class) inflammation. Mammalian cells…”
Get full text

Peroxisome proliferator‐activated receptor γ agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc 1638 N/+ Mlh1 +/− double mutant mice by Yang, Kan, Fan, Kun‐Hua, Lamprecht, Sergio A., Edelmann, Winfried, Kopelovich, Levy, Kucherlapati, Raju, Lipkin, Martin

“…The role of the nuclear peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) in colon tumorigenesis remains controversial. Notwithstanding evidence that…”
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Peroxisome proliferator-activated receptor γ agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638N/+ Mlh1+/- double mutant mice by KAN YANG, FAN, Kun-Hua, LAMPRECHT, Sergio A, EDELMANN, Winfried, KOPELOVICH, Levy, KUCHERLAPATI, Raju, LIPKIN, Martin

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Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc super(1638 N/+) Mlh1 super(+/-) double mutant mice by Yang, Kan, Fan, Kun-Hua, Lamprecht, Sergio A, Edelmann, Winfried, Kopelovich, Levy, Kucherlapati, Raju, Lipkin, Martin

“…The role of the nuclear peroxisome proliferator-activated receptor- gamma (PPAR- gamma ) in colon tumorigenesis remains controversial. Notwithstanding evidence…”
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Controlled release of TGF‐β1 impedes rat colon carcinogenesis in vivo by Mikhailowski, Rachel, Shpitz, Baruch, Polak‐Charcon, Sylvie, Kost, Yoseph, Segal, Carmen, Fich, Alexander, Lamprecht, Sergio A.

“…Transforming growth factor β1 (TGF‐β1) is a cytokine known to play a key role in the control of cell growth. TGF‐β1 potently inhibits the proliferation of…”
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Controlled release of TGF-β1 impedes rat colon carcinogenesisin vivo by Mikhailowski, Rachel, Shpitz, Baruch, Polak-Charcon, Sylvie, Kost, Yoseph, Segal, Carmen, Fich, Alexander, Lamprecht, Sergio A.

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Extensive apoptotic death of rat colonic cells deprived of crypt habitat by Lifshitz, Sarit, Schwartz, Betty, Polak-Charcon, Sylvie, Benharroch, Daniel, Prinsloo, Isebrand, Lamprecht, Sergio A.

“…Apoptosis in cells of different lineages is restrained by survival signals which depend upon cell‐to‐cell communication. The aim of this study was to determine…”
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