Search Results - "LAMBOOY, Lambert H. J"

Quantitative proteome profiling of respiratory virus-infected lung epithelial cells by van Diepen, Angela, Brand, H. Kim, Sama, Iziah, Lambooy, Lambert H.J., van den Heuvel, Lambert P., van der Well, Leontine, Huynen, Martijn, Osterhaus, Albert D.M.E., Andeweg, Arno C., Hermans, Peter W.M.

“…Respiratory virus infections are among the primary causes of morbidity and mortality in humans. Influenza virus, respiratory syncytial virus (RSV),…”
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Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects by Brouwer, Connie, De Abreu, Ronney A., Keizer-Garritsen, Jenneke J., Lambooy, Lambert H.J., Ament, Kai, ter Riet, Patricia G.J.H., van Wering, Elisabeth R., Trijbels, Frans J.M., Veerman, Anjo J.P., Hoogerbrugge, Peter M., Bökkerink, Jos P.M.

“…Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme, catalysing S-methylation of aromatic and heterocyclic sulphhydryl compounds. TPMT activities and…”
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Real-time analysis of Tyrosine hydroxylase gene expression: A sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma by LAMBOOY, Lambert H. J, GIDDING, Corrie E. M, VAN DEN HEUVEL, Lambert P, HULSBERGEN-VAN DE KAA, Christina A, LIGTENBERG, Marjolijn, BÖKKERINK, Jos P. M, DE ABREU, Ronney A

“…The purpose of this study was to establish a sensitive and semiquantitative method for the detection of minimal residual disease of neuroblastoma, the most…”
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Measurement of thiopurine S-methyltransferase activity in human blood samples based on high-performance liquid chromatography: reference values in erythrocytes from children by Keizer-Garritsen, Jenneke J, Brouwer, Connie, Lambooy, Lambert H J, Ter Riet, Patricia, Bökkerink, Jos P M, Trijbels, Frans J M, De Abreu, Ronney A

“…Monitoring 6-thiopurine S-methyltransferase (TPMT; EC 2.1.1.67) activity is especially important when patients are treated with 6-thiopurine drugs, since…”
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Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis by De Abreu, Ronney A, Trueworthy, Robert C, van Kuilenburg, André B P, Vogels-Mentink, Trude M, Lambooy, Lambert H J, van Gennip, Albert H

“…Methotrexate (MTX) followed by 6-mercaptopurine (6MP) is one of the best known combinations for the treatment of childhood acute lymphoblastic leukaemia…”
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Inhibition of DNA methylation in malignant MOLT F4 lymphoblasts by 6-mercaptopurine by Lambooy, Lambert H. J, Leegwater, Peter A. J, van den Heuvel, Lambert P, Bokkerink, Jos P, De Abreu, Ronney A

“…Treatment of MOLT F4 lymphoblasts with 6-mercaptopurine (6-MP) resulted in a decrease of ATP and a depletion of S-adenosylmethionine (AdoMet). To investigate…”
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Real-Time Analysis of Tyrosine Hydroxylase Gene Expression by Lambert H. J. Lambooy, Corrie E. M. Gidding, Lambert P. van den Heuvel, Christina A. Hulsbergen-van de Kaa, Marjolijn Ligtenberg, Jos P. M. Bökkerink, Ronney A. De Abreu

“…Purpose: The purpose of this study was to establish a sensitive and semiquantitativemethod for the detection of minimal residual diseaseof neuroblastoma, the…”
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Azathioprine-related bone marrow toxicity and low activities of purine enzymes in patients with rheumatoid arthritis by Kerstens, P J, Stolk, J N, De Abreu, R A, Lambooy, L H, van de Putte, L B, Boerbooms, A A

“…Azathioprine (AZA) metabolism largely parallels the endogenous purine pathways. To date, thiopurine methyltransferase (TPMT) deficiency has been reported as a…”
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Inhibition of IMP dehydrogenase by mycophenolic acid in Molt F4 human malignant lymphoblasts by Stet, E H, De Abreu, R A, Bökkerink, J P, Lambooy, L H, Vogels-Mentink, T M, Keizer-Garritsen, J J, Trijbels, F J

“…The effects of inhibition of inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in guanine nucleotide de novo synthesis, on cell growth,…”
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