Search Results - "LAMBERT, P. F"

The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer by Richard, C, Lanner, C, Naryzhny, S N, Sherman, L, Lee, H, Lambert, P F, Zehbe, I

“…Persistent infection with high-risk human papillomaviruses (HPVs), especially type 16 has been undeniably linked to cervical cancer. The Asian-American (AA)…”
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HPV16 E6 confers p53-dependent and p53-independent phenotypes in the epidermis of mice deficient for E6AP by SHAI, A, NGUYEN, M. L, WAGSTAFF, J, JIANG, Y.-H, LAMBERT, P. F

“…High-risk human papillomaviruses are the causative agents of cervical and other anogenital cancers. In these cancers, two viral oncogenes, E6 and E7, are…”
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Differential gene expression between skin and cervix induced by the E7 oncoprotein in a transgenic mouse model by Ibarra Sierra, E, Díaz Chávez, J, Cortés-Malagón, E.M, Uribe-Figueroa, L, Hidalgo-Miranda, A, Lambert, P.F, Gariglio, P

“…Abstract HPV16 E7 oncoprotein expression in K14E7 transgenic mice induces cervical cancer after 6 months of treatment with the co-carcinogen 17β-estradiol. In…”
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Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells by Jeon, S, Allen-Hoffmann, B L, Lambert, P F

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Evidence for a switch in the mode of human papillomavirus type 16 DNA replication during the viral life cycle by Flores, E R, Lambert, P F

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Centrosome Abnormalities and Genomic Instability by Episomal Expression of Human Papillomavirus Type 16 in Raft Cultures of Human Keratinocytes by Duensing, S, Duensing, A, Flores, E R, Do, A, Lambert, P F, Münger, K

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Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene by Herber, R, Liem, A, Pitot, H, Lambert, P F

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High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7’s induction of DNA damage response, an activity mediated by E7’s inactivation of pocket proteins by Park, J W, Shin, M-K, Lambert, P F

“…Fanconi anemia (FA) is a rare genetic disorder caused by defects in a DNA damage repair system, the FA pathway. FA patients frequently develop squamous cell…”
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Gene expression profile of cervical and skin tissues from human papillomavirus type 16 E6 transgenic mice by Mendoza-Villanueva, D, Diaz-Chavez, J, Uribe-Figueroa, L, Rangel-Escareão, C, Hidalgo-Miranda, A, March-Mifsut, S, Jimenez-Sanchez, G, Lambert, Pf, Gariglio, P

“…Although K14E6 transgenic mice develop spontaneous tumors of the skin epithelium, no spontaneous reproductive tract malignancies arise, unless the transgenic…”
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DEK promotes HPV-positive and -negative head and neck cancer cell proliferation by Adams, A K, Hallenbeck, G E, Casper, K A, Patil, Y J, Wilson, K M, Kimple, R J, Lambert, P F, Witte, D P, Xiao, W, Gillison, M L, Wikenheiser-Brokamp, K A, Wise-Draper, T M, Wells, S I

“…Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, and patient outcomes using current treatments remain poor. Tumor…”
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Different Responses of Epidermal and Hair Follicular Cells to Radiation Correlate with Distinct Patterns of p53 and p21 Induction by Song, Shiyu, Lambert, Paul F.

“…Different parts of the skin respond to ionizing radiation with different sensitivities. To examine the mechanisms underlying these different responses, we…”
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Cell Cycle Regulation of Human Interleukin-8 Gene Expression by the Human Immunodeficiency Virus Type 1 Tat Protein by Mahieux, R, Lambert, P F, Agbottah, E, Halanski, M A, Deng, L, Kashanchi, F, Brady, J N

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Tumorigenicity by human papillomavirus type 16 E6 and E7 in transgenic mice correlates with alterations in epithelial cell growth and differentiation by GRIEP, A. E, HERBER, R, JEON, S, LOHSE, J. K, DUBIELZIG, R. R, LAMBERT, P. F

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Epidermal Cancer Associated with Expression of Human Papillomavirus Type 16 E6 and E7 Oncogenes in the Skin of Transgenic Mice by Lambert, Paul F., Pan, Huichin, Pitot, Henry C., Liem, Amy, Jackson, Mark, Griep, Anne E.

“…Certain "high-risk" anogenital human papillomaviruses (HPVs) have been associated with the majority of human cervical carcinomas. In these cancers, two…”
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The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex by DOSTATNI, N, LAMBERT, P. F, SOUSA, R, HAM, J, HOWLEY, P. M, YANIV, M

“…The products encoded by the E2 open reading frame of the papillomaviruses are DNA-binding transcription factors involved in the positive or negative regulation…”
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Integration of Human Papillomavirus Type 16 DNA into the Human Genome Leads to Increased Stability of E6 and E7 mRNAs: Implications for Cervical Carcinogenesis by Jeon, Saewha, Lambert, Paul F.

“…In many cervical cancers, human papillomavirus type 16 (HPV-16) DNA genomes are found to be integrated into the host chromosome. In this study, we demonstrate…”
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A fourth Sp1 site in the human immunodeficiency virus type 1 long terminal repeat is essential for negative-sense transcription by Peeters, A, Lambert, P F, Deacon, N J

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Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis by RILEY, Rebeccah R, DUENSING, Stefan, BRAKE, Tiffany, MÜNGER, Karl, LAMBERT, Paul F, ARBEIT, Jeffrey M

“…Human cervix cancer is caused by high-risk human papillomaviruses encoding E6 and E7 oncoproteins, each of which alter function of distinct targets regulating…”
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Papillomavirus DNA replication by Lambert, P.F. (University of Wisconsin, Madison, WI)

“…The capacity for bovine papillomavirus type 1 (BPV-1) to transform rodent cells in tissue culture has provided a system for studying regulated replication of a…”
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Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization by DOAN, T, HERD, K. A, LAMBERT, P. F, FERNANDO, G. J. P, STREET, M. D, TINDLE, R. W

“…The E7 oncoprotein of human papillomavirus 16 functions as a tumor-specific antigen in transformed epithelial cells of the uterine cervix to which…”
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