Search Results - "LAKTIONOV, K. K"
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Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma
Published in PloS one (09-10-2013)“…Lung cancer is the major human malignancy, accounting for 30% of all cancer-related deaths worldwide. Poor survival of lung cancer patients, together with late…”
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2
Use of selpercatinib in a patient with RET-mutated non-small cell lung cancer: case report
Published in Sibirskiĭ onkologicheskiĭ zhurnal (12-05-2024)“…Background . The use of the modern targeted drugs in patients with non-small-cell lung cancer (NSCLC) with certain somatic alterations (genetic alterations in…”
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3
KRAS-mutated non-small cell lung cancer: new therapy strategies
Published in Sibirskiĭ onkologicheskiĭ zhurnal (12-05-2024)“…Lung cancer remains one of the most dangerous and most common cancers, requiring constant improvement of diagnostic and treatment methods. The genetic…”
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4
Nivolumab with Ipilimumab in the treatment of refractory hepatocellular carcinoma
Published in Medicinskij sovet (19-06-2022)“…HCC is considered refractory when it comes to progression during treatment with TKIs (sorafenib, lenvatinib). The combined immunotherapy of nivolumab with…”
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Adjuvant immunotherapy of operable non-small cell lung cancer: achievements and treatment prospects
Published in Medicinskij sovet (18-06-2022)“…Lung cancer is one of the most common malignant tumors with the highest mortality, with about 85% of cases of the disease being non-small cell lung cancer. To…”
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Efficacy of lorlatinib in the treatment of ALK-positive non-small cell lung cancer patients with progression on crizotinib: personal experience
Published in Medicinskij sovet (10-12-2021)“…Introduction . Lorlatinib is a third generation ALK tyrosine kinase inhibitor. Back in 2018, the drug underwent accelerated FDA approval and was recommended…”
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Evaluation and modifcation of lung immune prognostic index in patients with metastatic NSCLC treated by immunotherapy
Published in Sibirskiĭ onkologicheskiĭ zhurnal (01-05-2023)“…Aim of the study : to evaluate prognostic value of baseline lung immune prognostic index (LIPI) and its modification (mLIPI) for metastatic non-small cell lung…”
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Second-line treatment of hepatocellular carcinoma: from theory to practical issues
Published in Medicinskij sovet (09-12-2019)“…Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer with unmet needs of effective medications. Lenvatinib – a new oral multikinase…”
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Рembrolizumab as second line therapy for hepatocellular patient
Published in Medicinskij sovet (12-12-2021)“…The optimal hepatocellular cancer (HCC) therapy remains a challenge. Due to checkpoint inhibitors patients with intolerance to the targeted therapy and or…”
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Three-year results of application of nivolumab in patients with non-small cell lung cancer in clinical practice of the N.N. Blokhin Russian Cancer Research Center
Published in Medicinskij sovet (09-12-2019)“…Non-small cell lung cancer (NSCLC) is the leading cause of death from cancer worldwide. Despite the success over recent years in the treatment of NSCLC it has…”
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Ceritinib in the treatment of ALK-positive patients with nonsmall-cell lung cancer
Published in Medicinskij sovet (24-06-2019)“…Ceritinib is the second ALK tyrosine kinase inhibitor after crizotinib, registered in the Russian Federation for the treatment of ALKpositive patients with…”
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12
Long-term disease control in a patient with ALK-positive non-small cell lung cancer
Published in Medicinskij sovet (19-06-2022)“…Non-small cell lung cancer is a very heterogeneous group of diseases. When choosing an effective patient management strategy, an oncologist focuses on the…”
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Mutation in the kras gene as a predictor of the effectiveness of immunotherapy for non-small cell lung cancer
Published in Sibirskiĭ onkologicheskiĭ zhurnal (03-03-2022)“…The purpose of the study: to conduct a systematic literature review on the effectiveness and feasibility of using information on the presence of KRAS gene…”
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Five-year results of nivolumab for the treatment of non-small cell lung cancer in clinical practice of the N.N. Blokhin Russian Cancer Research Center
Published in Medicinskij sovet (07-08-2021)“…Introduction . Lung cancer remains the one of the most common and fatal cancers in the world. For a long time, chemotherapy was the only treatment option…”
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Immunotherapy for hepatocellular cancer: beginning and future perspectives
Published in Medicinskij sovet (24-06-2019)“…Hepatocellular cancer (HCC) is a significant problem of modern Oncology. Until recently, sorafenib was the only drug in the treatment of locally advanced and…”
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A clinical case of 3-year highly efficient pembrolizamable therapy of metasatic lung adenocarcinoma
Published in Medicinskij sovet (19-07-2018)“…Immunotherapy presents a new promising approach to the treatment of disseminated lung cancer. Pemriblisumab (Kitruda®) is one of the antiPD-1 drugs registered…”
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A preliminary results of integrated chemotherapy with EGFR receptor tyrosine kinase inhibitors in patients with non-small-cell-lung cancer harboring EGFR mutation
Published in Medicinskij sovet (24-06-2019)“…In the open prospective non-randomized single-center study we recruited patients with advanced NSCLC harboring EGFR mutations. Initially there were two months…”
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Design of targeted next-generation sequencing (NGS) of circulating tumour DNA (ctDNA): towards overcoming DNA
Published in Annals of oncology (01-10-2017)Get full text
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Clinical case of use of osimertinib in a patient with disseminated EGFR-mutated non-small cell lung cancer in the first-line therapy
Published in Medicinskij sovet (21-12-2020)“…Osimertinib is a third-generation tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR) that has been approved for the treatment of…”
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Afatinib in EGFR TKI-Naïve Patients with Locally Advanced or Metastatic EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Pooled Analysis of Three Phase IIIb Studies
Published in Frontiers in oncology (09-07-2021)“…Background Afatinib is approved for first-line treatment of patients with epidermal growth factor receptor mutation-positive ( EGFR m+) non-small-cell lung…”
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