Search Results - "LAKATOS, P"
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Characterization of and Risk Factors for the Acute-Phase Response after Zoledronic Acid
Published in The journal of clinical endocrinology and metabolism (01-09-2010)“…Context: Intravenous aminobisphosphonates often cause an acute-phase response (APR), but the precise components of this, its frequency, and the risk factors…”
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Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target
Published in The American journal of gastroenterology (01-09-2015)“…The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) program was initiated by the International Organization for the Study of Inflammatory…”
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3
Neural mechanisms of mismatch negativity dysfunction in schizophrenia
Published in Molecular psychiatry (01-11-2017)“…Schizophrenia is associated with cognitive deficits that reflect impaired cortical information processing. Mismatch negativity (MMN) indexes pre-attentive…”
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Differential Ganglioside and Cholesterol Depletion by Various Cyclodextrin Derivatives and Their Effect on Synaptosomal Glutamate Release
Published in International journal of molecular sciences (21-08-2022)“…Gangliosides are glycosphingolipids of the plasma membrane and are highly enriched in the nervous system where they play a vital role in normal cell functions…”
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Patient-Reported Outcomes in Inflammatory Bowel Diseases: Another Piece in the Puzzle
Published in Journal of Crohn's and colitis (05-07-2021)Get full text
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East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort
Published in Gut (01-04-2014)“…The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. The reasons for these changes remain unknown. The aim of this study was to…”
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The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study
Published in Osteoporosis international (01-12-2015)“…Summary The FREEDOM study and its Extension provide long-term information about the effects of denosumab for the treatment of postmenopausal osteoporosis…”
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Separation of tolperisone and its degradation products by a dual cyclodextrin capillary electrophoresis system to study their potential role in allergic events
Published in Journal of pharmaceutical and biomedical analysis (01-01-2025)“…Tolperisone is a centrally acting muscle relaxant that has been used for the treatment of post-stroke spasticity and low back pain. Recently, the safety of…”
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The Acute Antiallodynic Effect of Tolperisone in Rat Neuropathic Pain and Evaluation of Its Mechanism of Action
Published in International journal of molecular sciences (01-09-2022)“…Current treatment approaches to manage neuropathic pain have a slow onset and their use is largely hampered by side-effects, thus there is a significant need…”
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Telmisartan Is a Promising Agent for Managing Neuropathic Pain and Delaying Opioid Analgesic Tolerance in Rats
Published in International journal of molecular sciences (27-04-2023)“…Despite the large arsenal of analgesic medications, neuropathic pain (NP) management is not solved yet. Angiotensin II receptor type 1 (AT1) has been…”
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Time to onset of bisphosphonate‐related osteonecrosis of the jaws: a multicentre retrospective cohort study
Published in Oral diseases (01-05-2017)“…Objectives Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates (BP). Although the risk of ONJ increases with increasing…”
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Review article: the natural history of paediatric‐onset ulcerative colitis in population‐based studies
Published in Alimentary pharmacology & therapeutics (01-02-2016)“…Summary Background A better knowledge of the natural history of disabling chronic diseases is essential to improve patient management, evaluate the impact of…”
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Early clinical remission and normalisation of CRP are the strongest predictors of efficacy, mucosal healing and dose escalation during the first year of adalimumab therapy in Crohn’s disease
Published in Alimentary pharmacology & therapeutics (01-10-2011)“…Aliment Pharmacol Ther 2011; 34: 911–922 Summary Background Adalimumab is a fully human monoclonal antibody targeting tumour necrosis factor with proven…”
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Predictors of relapse in patients with Crohn's disease in remission after 1 year of biological therapy
Published in Alimentary pharmacology & therapeutics (01-01-2013)“…Summary Background Some of the most important questions relating to the use of biological therapy in inflammatory bowel diseases concern the duration of…”
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Is there an increased risk of lymphoma and malignancies under anti-TNF therapy in IBD?
Published in Current drug targets (01-02-2010)“…Tumour necrosis factor alpha (TNF-alpha) inhibitors ensure valuable treatment advantages for patients with inflammatory bowel diseases (IBD) by offering a more…”
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Pharmacological Evidence on Augmented Antiallodynia Following Systemic Co-Treatment with GlyT-1 and GlyT-2 Inhibitors in Rat Neuropathic Pain Model
Published in International journal of molecular sciences (01-03-2021)“…The limited effect of current medications on neuropathic pain (NP) has initiated large efforts to develop effective treatments. Animal studies showed that…”
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Predictive suppression of cortical excitability and its deficit in schizophrenia
Published in The Journal of neuroscience (10-07-2013)“…Recent neuroscience advances suggest that when interacting with our environment, along with previous experience, we use contextual cues and regularities to…”
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Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis
Published in The New England journal of medicine (03-05-2007)“…In this double-blind, placebo-controlled trial, women with postmenopausal osteoporosis received an infusion of either zoledronic acid (5 mg) or placebo at…”
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The effect of L-theanine and S-ketamine on d-serine cellular uptake
Published in Biochimica et biophysica acta. Proteins and proteomics (01-10-2020)“…Decreased extracellular level of d-Serine (D-Ser), a co-agonist of the N-methyl-d-aspartate (NMDA) receptors was connected to receptor hypofunction in the…”
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Pregabalin–Tolperisone Combination to Treat Neuropathic Pain: Improved Analgesia and Reduced Side Effects in Rats
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2023)“…The current treatment of neuropathic pain (NP) is unsatisfactory; therefore, effective novel agents or combination-based analgesic therapies are needed…”
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