Search Results - "LAITINEN, TARJA"
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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
Published in Nature genetics (01-03-2019)“…Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease…”
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Motor vehicle accidents in CPAP-compliant obstructive sleep apnea patients—a long-term observational study
Published in Sleep & breathing (01-09-2020)“…Purpose Obstructive sleep apnea (OSA) has been associated with a 2- to 7-fold risk of motor vehicle accidents (MVAs). Continuous positive airway pressure…”
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Home non-invasive ventilation: An observational study of aetiology, chronic respiratory failure of multiple aetiologies, survival and treatment adherence
Published in Heliyon (30-06-2024)“…Home non-invasive ventilation (NIV) is used to treat patients with chronic respiratory failure (CRF). However, knowledge on the prevalence and impact of…”
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Global energy consumption due to friction in paper machines
Published in Tribology international (01-06-2013)“…Calculations on the global energy consumption used to overcome friction in paper machines in terms of friction in motors, transmissions, pumps, blowers,…”
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High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study
Published in Neoplasia (New York, N.Y.) (01-09-2020)“…Tumor mutation burden (TMB) is an emerging predictive cancer biomarker. Few studies have addressed the prognostic role of TMB in non-small cell lung carcinoma,…”
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Use of electronic health record data mining for heart failure subtyping
Published in BMC research notes (11-09-2023)“…Abstract Objective To assess whether electronic health record (EHR) data text mining can be used to improve register-based heart failure (HF) subtyping. EHR…”
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Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA
Published in PloS one (28-09-2012)“…Asthma has substantial morbidity and mortality and a strong genetic component, but identification of genetic risk factors is limited by availability of…”
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Documentation of the patient's smoking status in common chronic diseases - analysis of medical narrative reports using the ULMFiT based text classification
Published in European clinical respiratory journal (01-01-2021)“…Smoking cessation is essential part of a successful treatment in many chronic diseases. Our aim was to analyse how actively clinicians discuss and document…”
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Response to letter entitled “CPAP adherence and cardiovascular disease: beware of the healthy adherer effect”
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Retrospective Evaluation of Lung Adenocarcinoma Patients Progressing on 1st Line Chemotherapy
Published in Medicina (Kaunas, Lithuania) (16-11-2019)“…Evaluation of data from electronic health care records could help in guiding towards more rational drug treatments. This single center study evaluated clinical…”
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Co-morbidities are the key nominators of the health related quality of life in mild and moderate COPD
Published in BMC pulmonary medicine (19-06-2014)“…Co-morbidities are common in chronic obstructive pulmonary disease (COPD). We assessed the contribution of common co-morbidities on health related quality of…”
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Characterization of a Common Susceptibility Locus for Asthma-Related Traits
Published in Science (American Association for the Advancement of Science) (09-04-2004)“…Susceptibility to asthma depends on variation at an unknown number of genetic loci. To identify susceptibility genes on chromosome 7p, we adopted a…”
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Characterization of sputum biomarkers for asthma-COPD overlap syndrome
Published in International journal of chronic obstructive pulmonary disease (01-01-2016)“…Asthma-COPD overlap syndrome (ACOS) is a commonly encountered chronic airway disease. However, ACOS is still a consensus-based clinical phenotype and the…”
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Normal values for the Pelli-Robson contrast sensitivity test
Published in Journal of cataract and refractive surgery (01-02-2001)“…To define normal values for the Pelli-Robson contrast sensitivity test in different age groups. University Eye Clinic of Kuopio, Kuopio, Finland. Contrast…”
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Improved risk prediction of chemotherapy‐induced neutropenia—model development and validation with real‐world data
Published in Cancer medicine (Malden, MA) (01-02-2022)“…Background The existing risk prediction models for chemotherapy‐induced febrile neutropenia (FN) do not necessarily apply to real‐life patients in different…”
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Forced Vital Capacity (FVC) decline, mortality and healthcare resource utilization in idiopathic pulmonary fibrosis
Published in European clinical respiratory journal (01-01-2020)“…Aim of the study: Potential care implications of antifibrotic reimbursement restrictions were studied by forced vital capacity (FVC) decline, mortality and…”
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Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes
Published in Communications biology (23-02-2022)“…Large-scale biobank initiatives and commercial repositories store genomic data collected from millions of individuals, and tools to leverage the rapidly…”
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Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics
Published in Cell genomics (12-10-2022)“…The research of rare and devastating orphan diseases, such as idiopathic pulmonary fibrosis (IPF) has been limited by the rarity of the disease itself. The…”
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Localized corrosion of stainless steel in chloride, sulfate and thiosulfate containing environments
Published in Corrosion science (01-03-2000)“…Localized corrosion behavior of UNS S30403 type stainless steel was studied by cyclic polarization scans, scratch tests and Contact Electric Resistance (CER)…”
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