Search Results - "LAGORCE, Christine"

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome by Galon, Jérôme, Costes, Anne, Sanchez-Cabo, Fatima, Kirilovsky, Amos, Mlecnik, Bernhard, Lagorce-Pagès, Christine, Tosolini, Marie, Camus, Matthieu, Berger, Anne, Wind, Philippe, Zinzindohoué, Franck, Bruneval, Patrick, Cugnenc, Paul-Henri, Trajanoski, Zlatko, Fridman, Wolf-Herman, Pagès, Franck

“…The role of the adaptive immune response in controlling the growth and recurrence of human tumors has been controversial. We characterized the…”
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In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer by Pagès, Franck, Kirilovsky, Amos, Mlecnik, Bernhard, Asslaber, Martin, Tosolini, Marie, Bindea, Gabriela, Lagorce, Christine, Wind, Philippe, Marliot, Florence, Bruneval, Patrick, Zatloukal, Kurt, Trajanoski, Zlatko, Berger, Anne, Fridman, Wolf-Herman, Galon, Jérôme

“…Many patients who present with early-stage colorectal cancer (International Union Against Cancer TNM stages I and II) are nevertheless at high risk of relapse…”
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The consensus immunoscore: toward a new classification of colorectal cancer by Lanzi, Anastasia, Pagès, Franck, Lagorce-Pagès, Christine, Galon, Jérôme

“…In its latest edition, the WHO classification of the Digestive System Tumors introduced for the first time the immune response as essential and desirable…”
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Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge by Pernot, Simon

“…While the incidence of gastric cancer has decreased worldwide in recent decades,the incidence of signetring cell carcinoma(SRCC) is rising. SRCC has a specific…”
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CARMN‐NOTCH2 fusion transcript drives high NOTCH2 expression in glomus tumors of the upper digestive tract by Girard, Nicolas, Marin, Cristi, Hélias‐Rodzewicz, Zofia, Villa, Chiara, Julié, Catherine, Lajarte‐Thirouard, Anne‐Sophie, Beauce, Simon Martin, Lagorce‐Pages, Christine, Renaud, Florence, Cazals‐Hatem, Dominique, Guedj, Nathalie, Cros, Jérome, Raffin‐Sanson, Marie‐Laure, Selves, Janick, Terris, Benoit, Fléjou, Jean‐François, Garchon, Henri‐Jean, Coindre, Jean‐Michel, Emile, Jean‐François

“…Glomus tumors (GTs) are perivascular tumors mostly occurring in the distal extremities. Rare cases arise in the digestive tract and may be misdiagnosed with…”
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Delayed retroperitoneal liposarcoma diagnosis and management in a patient with massive obesity by Rives-Lange, Claire, Poghosyan, Tigran, Dariane, Charles, Douard, Richard, Mongeois, Elise, Boudaoud, Amel Ait, Barsamian, Charles, Radu, Alina, Lagorce, Christine, Verkarre, Virginie, Larousserie, Frédérique, Perregaux, Jean-François, Joly, Fransisca, Carette, Claire, Czernichow, Sébastien

“…People suffering from extreme obesity may be exposed to delayed diagnosis and treatment of cancer. A 37-year-old woman (weight = 245 kg, body mass index (BMI)…”
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Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer by Marliot, Florence, Chen, Xiaoyi, Kirilovsky, Amos, Sbarrato, Thomas, El Sissy, Carine, Batista, Luciana, Van den Eynde, Marc, Haicheur-Adjouri, Nacilla, Anitei, Maria-Gabriela, Musina, Ana-Maria, Scripcariu, Viorel, Lagorce-Pagès, Christine, Hermitte, Fabienne, Galon, Jérôme, Fieschi, Jacques, Pagès, Franck

“…BackgroundNew and fully validated tests need to be brought into clinical practice to improve the estimation of recurrence risk in patients with colon cancer…”
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Expression of ghrelin in fundus is increased after gastric banding in morbidly obese patients by Uzzan, Bernard, Catheline, Jean-Marc, Lagorce, Christine, Airinei, Gheorghe, Bon, Cyriaque, Cohen, Régis, Perret, Gérard-Yves, Aparicio, Thomas, Benamouzig, Robert

“…Ghrelin, a 28 amino-acid acylated orexigenic peptide secreted by the stomach, acts on the hypothalamic arcuate nucleus which stimulates feeding behavior. Serum…”
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International Validation of the Immunoscore Biopsy in Patients With Rectal Cancer Managed by a Watch-and-Wait Strategy by El Sissy, Carine, Kirilovsky, Amos, Lagorce Pagès, Christine, Marliot, Florence, Custers, Petra A, Dizdarevic, Edina, Sroussi, Marine, Castillo-Martin, Mireia, Haicheur, Nacilla, Dermani, Mohamed, Loche, Nicolas, Buttard, Bénedicte, Musina, Ana Maria, Anitei, Maria Gabriela, van den Berg, José G, Broeks, Annegien, Iseas, Soledad, Coraglio, Mariana, Loria, Fernando Sanchez, Romero, Alfredo, Laurent-Puig, Pierre, de Reyniès, Aurélien, Fernandez, Laura M, Karoui, Mehdi, Tougeron, David, Vaccaro, Carlos A, Santino, Juan P, Poulsen, Laurids Østergaard, Lindebjerg, Jan, O'Connor, Juan Manuel, Scripcariu, Viorel, Dimofte, Mihail-Gabriel, Gérard, Jean-Pierre, Chalabi, Myriam, Figueiredo, Nuno, Perez, Rodrigo O, Habr-Gama, Angelita, Galon, Jérôme, Hansen, Torben Frøstrup, Jensen, Lars Henrik, Beets, Geerard, Zeitoun, Guy, Pagès, Franck

“…No biomarker capable of improving selection and monitoring of patients with rectal cancer managed by watch-and-wait (W&W) strategy is currently available…”
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Therapeutic Implications of the Immunoscore in Patients with Colorectal Cancer by El Sissy, Carine, Kirilovsky, Amos, Zeitoun, Guy, Marliot, Florence, Haicheur, Nacilla, Lagorce-Pagès, Christine, Galon, Jérôme, Pagès, Franck

“…Four decades were needed to progress from the first demonstration of the independent prognostic value of lymphocytes infiltration in rectal cancers to the…”
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International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study by Pagès, Franck, Mlecnik, Bernhard, Marliot, Florence, Bindea, Gabriela, Ou, Fang-Shu, Bifulco, Carlo, Lugli, Alessandro, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia Y, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia K, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Fredriksen, Tessa, Buttard, Bénédicte, Angelova, Mihaela, Vasaturo, Angela, Maby, Pauline, Church, Sarah E, Angell, Helen K, Lafontaine, Lucie, Bruni, Daniela, El Sissy, Carine, Haicheur, Nacilla, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Meyers, Jeffrey P, Paustian, Christopher, Feng, Zipei, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Mușină, Ana-Maria, Scripcariu, Dragos-Viorel, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Torigoe, Toshihiko, Sato, Noriyuki, Furuhata, Tomohisa, Takemasa, Ichiro, Itoh, Kyogo, Patel, Prabhu S, Vora, Hemangini H, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Kawakami, Yutaka, Marincola, Francesco M, Ascierto, Paolo A, Sargent, Daniel J, Fox, Bernard A, Galon, Jérôme

“…The estimation of risk of recurrence for patients with colon carcinoma must be improved. A robust immune score quantification is needed to introduce immune…”
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Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer by ANITEI, Maria-Gabriela, ZEITOUN, Guy, DANCIU, Mihai, BRUNEVAL, Patrick, SCRIPCARIU, Viorel, CHEVALLIER, Jean-Marc, ZINZINDOHOUE, Franck, BERGER, Anne, GALON, Jérôme, PAGES, Franck, MLECNIK, Bernhard, MARLIOT, Florence, HAICHEUR, Nacilla, TODOSI, Ana-Maria, KIRILOVSKY, Amos, LAGORCE, Christine, BINDEA, Gabriela, FERARIU, Dan

“…To determine whether the tumor immune infiltrate, as recently evaluated with the Immunoscore methodology, could be a useful prognostic marker in patients with…”
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Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer by Mlecnik, Bernhard, Bifulco, Carlo, Bindea, Gabriela, Marliot, Florence, Lugli, Alessandro, Lee, J Jack, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia Y, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia K, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Fredriksen, Tessa, Buttard, Bénédicte, Lafontaine, Lucie, Bruni, Daniela, Lanzi, Anastasia, El Sissy, Carine, Haicheur, Nacilla, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Paustian, Christopher, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Muşină, Ana-Maria, Scripcariu, Dragos-Viorel, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Torigoe, Toshihiko, Sato, Noriyuki, Furuhata, Tomohisa, Takemasa, Ichiro, Itoh, Kyogo, Patel, Prabhu S, Vora, Hemangini H, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Kawakami, Yutaka, Marincola, Francesco M, Ascierto, Paolo A, Fox, Bernard A, Pagès, Franck, Galon, Jérôme

“…The purpose of this study was to evaluate the prognostic value of Immunoscore in patients with stage III colon cancer (CC) and to analyze its association with…”
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Focus on the Immunoscore and its potential clinical implications by El Sissy, Carine, Marliot, Florence, Haicheur, Nacilla, Kirilovsky, Amos, Scripcariu, Dragos, Lagorce-Pagès, Christine, Galon, Jérôme, Pagès, Franck

“…The role of the immune response at the tumor site is now recognized as crucial in the clinical course of patients with cancer. The importance of the immune…”
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A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy by El Sissy, Carine, Kirilovsky, Amos, Van den Eynde, Marc, Muşină, Ana-Maria, Anitei, Maria-Gabriela, Romero, Alfredo, Marliot, Florence, Junca, Audelaure, Doyen, Jérôme, Mlecnik, Bernhard, Haicheur, Nacilla, Fredriksen, Tessa, Lagorce, Christine, Jouret-Mourin, Anne, Leonard, Daniel, Bibeau, Frédéric, Iseas, Soledad, Roca, Enrique L, Cabanne, Ana M, Vaccaro, Carlos A, Santino, Juan P, Huertas, Eduardo, Tougeron, David, Carvalho, Carlos, Figueiredo, Nuno, Perez, Rodrigo O, Habr-Gama, Angelita, Scripcariu, Viorel, Gerard, Jean-Pierre, Galon, Jérôme, Zeitoun, Guy, Pagès, Franck

“…No biomarker to personalize treatment in locally advanced rectal cancer (LARC) is currently available. We assessed in LARC whether a diagnostic biopsy-adapted…”
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Immune response and digestive cancers: Prognostic and therapeutic implications by Bibeau, Frédéric, Bazille, Céline, Svrcek, Magali, Pierson, Rémi, Lagorce-Pagès, Christine, Cohen, Romain, André, Thierry

“…The aim of this article is to emphasize the impact of the immune response in digestive cancers, especially from colorectal (CRC) origin. In this setting, an…”
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Cancer classification using the Immunoscore: a worldwide task force by Galon, Jérôme, Pagès, Franck, Marincola, Francesco M, Angell, Helen K, Thurin, Magdalena, Lugli, Alessandro, Zlobec, Inti, Berger, Anne, Bifulco, Carlo, Botti, Gerardo, Tatangelo, Fabiana, Britten, Cedrik M, Kreiter, Sebastian, Chouchane, Lotfi, Delrio, Paolo, Arndt, Hartmann, Asslaber, Martin, Maio, Michele, Masucci, Giuseppe V, Mihm, Martin, Vidal-Vanaclocha, Fernando, Allison, James P, Gnjatic, Sacha, Hakansson, Leif, Huber, Christoph, Singh-Jasuja, Harpreet, Ottensmeier, Christian, Zwierzina, Heinz, Laghi, Luigi, Grizzi, Fabio, Ohashi, Pamela S, Shaw, Patricia A, Clarke, Blaise A, Wouters, Bradly G, Kawakami, Yutaka, Hazama, Shoichi, Okuno, Kiyotaka, Wang, Ena, O'Donnell-Tormey, Jill, Lagorce, Christine, Pawelec, Graham, Nishimura, Michael I, Hawkins, Robert, Lapointe, Réjean, Lundqvist, Andreas, Khleif, Samir N, Ogino, Shuji, Gibbs, Peter, Waring, Paul, Sato, Noriyuki, Torigoe, Toshihiko, Itoh, Kyogo, Patel, Prabhu S, Shukla, Shilin N, Palmqvist, Richard, Nagtegaal, Iris D, Wang, Yili, D'Arrigo, Corrado, Kopetz, Scott, Sinicrope, Frank A, Trinchieri, Giorgio, Gajewski, Thomas F, Ascierto, Paolo A, Fox, Bernard A

“…Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation of tissue samples obtained during surgical resection of the…”
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Fatal Invasive Aspergillosis Complicating Severe Plasmodium falciparum Malaria by Hocqueloux, Laurent, Bruneel, Fabrice, Pages, Christine Lagorce, Vachon, François

“…We report the first 2 cases of fatal invasive aspergillosis complicating severe malaria. In 2 nonimmune European adults without underlying disease, death was…”
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International validation of the Immunoscore-biopsy (IS B ) to guide selection and monitoring of patients treated with watch-and-wait (WW) strategy for rectal cancer by Pages, Franck, El Sissy, Carine, Kirilovsky, Amos, Custers, Petra, Dizdarevic, Edina, Lagorce, Christine, Castillo-Martin, Mireia, van den Berg, José, Iseas, Soledad, Sanchez Loria, Fernando, Gerard, Jean-Pierre, Dimofte, Gabriel, Perez, Rodrigo O, Habr-Gama, Angelita, Figueiredo, Nuno, Hansen, Torben, Chalabi, Myriam, Galon, Jerome, Beets, Geerard, Zeitoun, Guy

“…3517 Background: The WW strategy for patients with rectal cancer who achieved a clinical complete response (cCR) after neoadjuvant therapy (nT) allows to avoid…”
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The consensus Immunoscore adapted to biopsies in patients with locally advanced rectal cancer: Potential clinical significance for a “Watch and Wait” strategy by El Sissy, Carine, Kirilovsky, Amos, Van Den Eynde, Marc, Romero, Alfredo, Marliot, Florence, Lagorce, Christine, Bibeau, Frédéric, Iseas, Ilma Soledad, Roca, Enrique Luis, Vaccaro, Carlos Alberto, Tougeron, David, Carvalho, Carlos Torres, Figueiredo, Nuno, Perez, Rodrigo O, Habr Gama, Angelita, Scripcariu, Viorel, Gerard, Jean-Pierre, Galon, Jerome, Zeitoun, Guy, Pages, Franck

“…Abstract only 2628 Background: We investigated whether an adaptation to rectal biopsies of the recently validated consensus Immunoscore, could predict the…”
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