Search Results - "LAGNADO, R"

P2X4 receptors interact with both P2X2 and P2X7 receptors in the form of homotrimers by Antonio, LS, Stewart, AP, Xu, XJ, Varanda, WA, Murrell‐Lagnado, RD, Edwardson, JM

“…BACKGROUND AND PURPOSE The P2X receptor family consists of seven subunit types – P2X1–P2X7. All but P2X6 are able to assemble as homotrimers. In addition,…”
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Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels by Ho, I H, Murrell-Lagnado, R D

“…G protein-gated inwardly rectifying K + (GIRK) channels are activated independently by Gβγ and internal Na + via mechanisms requiring phosphatidylinositol…”
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A protocol for low contamination risk of autologous serum drops in the management of ocular surface disorders by Lagnado, R, King, A J, Donald, F, Dua, H S

“…Aim: To assess microbial contamination of 20% autologous serum (AS) eye drops used in a hospital inpatient setting. Method: 14 patients received autologous…”
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Molecular Determinants for Sodium-dependent Activation of G Protein-gated K+ Channels by Ho, I H, Murrell-Lagnado, R D

“…G protein-gated inwardly rectifying K + channels (GIRKs) are activated by a direct interaction with Gβγ subunits and also by raised internal [Na + ]. Both…”
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P2X Receptor Trafficking in Neurons Is Subunit Specific by Bobanovic, Laura K, Royle, Stephen J, Murrell-Lagnado, Ruth D

“…P2X receptors within the CNS mediate excitatory synaptic transmission and also act presynaptically to modulate neurotransmitter release. We have studied the…”
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Xe991 reveals differences in K(+) channels regulating chloride secretion in murine airway and colonic epithelium by MacVinish, L J, Guo, Y, Dixon, A K, Murrell-Lagnado, R D, Cuthbert, A W

“…The cognitive enhancer XE991 interacts with K(+) channels consisting of KCNQ2 and KCNQ3 heteromultimers to block the M-current. XE991 can also block KCNQ1 K(+)…”
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Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides by MURRELL-LAGNADO, R. D, ALDRICH, R. W

“…Synthetic peptides of the five alternative NH2-terminal sequences of Shaker when applied to the cytoplasmic side of ShB channels that have an NH2-terminal…”
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A case of orbital myositis secondary to orbital cellulitis in a child by Manuchehri, K, Lagnado, R, Butler, L

“…Eye (2003) 17, 434-436. doi:10.1038/sj.eye.6700342…”
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Energetics of Shaker K channels block by inactivation peptides by MURRELL-LAGNADO, R. D, ALDRICH, R. W

“…A synthetic peptide of the NH2-terminal inactivation domain of the ShB channel blocks Shaker channels which have an NH2-terminal deletion and mimics many of…”
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Long term clinical outcome of a randomised controlled trial of anterior chamber lenses after high volume intracapsular cataract surgery by Hennig, A, Johnson, G J, Evans, J R, Lagnado, R, Poulson, A, Pradhan, D, Foster, A, Wormald, R P L

“…BACKGROUND Age related cataract remains the major cause of blindness throughout the world. In many countries, the majority of cataract surgery continues to be…”
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Randomized controlled trial of anterior-chamber intraocular lenses in Nepal : long-term follow-up by EVANS, J. R, HENNIG, A, PRADHAN, D, FOSTER, A, LAGNADO, R, POULSON, A, JOHNSON, G. J, WORMALD, R. P. L

“…Most of the estimated 20 million people who are blind with cataracts live in rural areas of developing countries, where expert surgical resources are scarce…”
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Management options for the flat corneal graft by Lagnado, R, Rubinstein, M.P, Maharajan, S, Dua, H.S

“…The post-penetrating keratoplasty (PK) corneal profile may be unpredictable and visual rehabilitation can be difficult. A case series of 11 such patients with…”
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Visualization of three-dimensional flow in a four-roll mill by LAGNADO, R. R, LEAL, L. G

“…Flow visualization has been used to study the motion of a Newtonian fluid in a four-roll mill. Observations of the effect of increasing Reynolds number on the…”
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Ultrastructural analysis of Phytomonas species from Euphorbia pinea reveals trans-cytoplasmic filaments 10 nm in diameter by PAGE, Anton M, LAGNADO, John R

“…Phytomonas sp. derived from Euphorbia pinea are digenetic plant trypanosomes that are transmitted by the squashbug Stenocephalus agilis and exist exclusively…”
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Phosphorylation in vivo of chick brain microtubule-associated phospholipids by LAGNADO, J. R, KIRAZOV, E

“…Microtubules were prepared by temperature-dependent cycles of assembly/disassembly from chick brain labeled in vivo with 32Pi and the distribution of labeled…”
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3A.04. Characterisation of a novel duplication mutation in KCNJ5 from a patient with an aldosterone producing adenoma by Hardege, I, Xu, S, Gordon, R.D, Thompson, A.J, Murrell-Lagnado, R, Stowasser, M, O'Shaughnessy, K.M

“…Accounting for 5-10% of hypertension, Primary Aldosteronism (PA) is a condition in which one or both adrenal glands autonomously produce aldosterone, either…”
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Effects of phenothiazine neuroleptic drugs on the microtubular-membrane complex in bloodstream forms of Trypanosoma brucei by Page, A M, Lagnado, J R

“…African trypanosomes are parasitic protozoa causing sleeping sickness in humans and related diseases in domestic animals against which no entirely satisfactory…”
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Clear cell basal carcinoma: an unusual variant by Reck, A, Pathmanathan, T, Lagnado, R, Parham, D M

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A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression by Gómez-Posada, Juan Camilo, Etxeberría, Ainhoa, Roura-Ferrer, Meritxell, Areso, Pilar, Masin, Marianela, Murrell-Lagnado, Ruth D, Villarroel, Alvaro

“…KCNQ2 (Kv7.2) and KCNQ3 (Kv7.3) are the principal subunits underlying the potassium M-current, which exerts a strong control on neuronal excitability. KCNQ3…”
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Identification of regions that regulate the expression and activity of G protein-gated inward rectifier K+ channels in Xenopus oocytes by Stevens, E B, Woodward, R, Ho, I H, Murrell-Lagnado, R

“…1. The involvement of the cytoplasmic and core regions of K+ channel Kir3.1 and Kir3.2 subunits in determining the cell surface expression and G protein-gated…”
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