Search Results - "LAGHI, FRANCO"
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Ultrasound and non-ultrasound imaging techniques in the assessment of diaphragmatic dysfunction
Published in BMC pulmonary medicine (15-03-2021)“…Diaphragm muscle dysfunction is increasingly recognized as an important element of several diseases including neuromuscular disease, chronic obstructive…”
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Inflammatory cytokines and cardiac arrhythmias: the lesson from COVID-19
Published in Nature reviews. Immunology (01-05-2022)“…Although inflammatory cytokines are implicated in the pathogenesis of cardiac arrhythmias, inflammation is still largely overlooked in the current management…”
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Caution about early intubation and mechanical ventilation in COVID-19
Published in Annals of intensive care (09-06-2020)Get full text
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Long-Term Acute Care Hospital Outcomes of Mechanically Ventilated Patients With Coronavirus Disease 2019
Published in Critical care medicine (01-02-2022)“…To describe the clinical characteristics and outcomes of adult patients with coronavirus disease 2019 requiring weaning from prolonged mechanical ventilation…”
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ERS statement on respiratory muscle testing at rest and during exercise
Published in The European respiratory journal (01-06-2019)“…Assessing respiratory mechanics and muscle function is critical for both clinical practice and research purposes. Several methodological developments over the…”
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Misconceptions of pathophysiology of happy hypoxemia and implications for management of COVID-19
Published in Respiratory research (24-09-2020)“…In the article "The pathophysiology of 'happy' hypoxemia in COVID-19," Dhont et al. (Respir Res 21:198, 2020) discuss pathophysiological mechanisms that may be…”
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Systemic Inflammation Rapidly Induces Reversible Atrial Electrical Remodeling: The Role of Interleukin-6-Mediated Changes in Connexin Expression
Published in Journal of the American Heart Association (20-08-2019)“…Background Systemic inflammation is a strong predictor of atrial fibrillation. A key role for electrical remodeling is increasingly recognized, and…”
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Emerging Arrhythmic Risk of Autoimmune and Inflammatory Cardiac Channelopathies
Published in Journal of the American Heart Association (20-11-2018)Get full text
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Systemic inflammation and arrhythmic risk: lessons from rheumatoid arthritis
Published in European heart journal (07-06-2017)“…Rheumatoid arthritis (RA) is a chronic immuno-mediated disease primarily affecting the joints, characterized by persistent high-grade systemic inflammation…”
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P-SILI is not justification for intubation of COVID-19 patients
Published in Annals of intensive care (03-08-2020)Get full text
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A Case Report of Cystic Fibrosis Plus Tuberous Sclerosis: A Cautionary Tale Regarding Lung Transplantation
Published in Transplantation proceedings (01-10-2021)“…•Co-occurrence of cystic fibrosis and tuberous sclerosis complex is exceedingly rare.•Cystic fibrosis may require pneumonectomy to control recurrent lung…”
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Basing intubation of acutely hypoxemic patients on physiologic principles
Published in Annals of intensive care (12-06-2024)“…The decision to intubate a patient with acute hypoxemic respiratory failure who is not in apparent respiratory distress is one of the most difficult clinical…”
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Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies
Published in Nature reviews. Immunology (01-01-2019)Get full text
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P-SILI as justification for intubation in COVID-19: readers as arbiters
Published in Annals of intensive care (18-11-2020)Get full text
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Pearls and pitfalls of respiratory testing in a patient with amyotrophic lateral sclerosis and COPD
Published in Breathe (Lausanne, Switzerland) (01-06-2023)“…Interpretation of pulmonary function testing in patients with amyotrophic lateral sclerosis must account for coexisting lung diseases, when making patient care…”
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Synthetic cannabinoid ajulemic acid exerts potent antifibrotic effects in experimental models of systemic sclerosis
Published in Annals of the rheumatic diseases (01-09-2012)“…Cannabinoids modulate fibrogenesis in scleroderma. Ajulemic acid (AjA) is a non-psychoactive synthetic analogue of tetrahydrocannabinol that can bind the…”
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Risk of QTc Interval Prolongation Associated With Circulating Anti-Ro/SSA Antibodies Among US Veterans: An Observational Cohort Study
Published in Journal of the American Heart Association (16-02-2021)“…Background Anti-Sjögren's syndrome-related antigen A-antibodies (anti-Ro/SSA-antibodies) are responsible for a novel form of acquired long-QT syndrome, owing…”
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Unravelling Atrioventricular Block Risk in Inflammatory Diseases: Systemic Inflammation Acutely Delays Atrioventricular Conduction via a Cytokine-Mediated Inhibition of Connexin43 Expression
Published in Journal of the American Heart Association (02-11-2021)“…Background Recent data suggest that systemic inflammation can negatively affect atrioventricular conduction, regardless of acute cardiac injury. Indeed,…”
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Validity and reliability of rectus femoris ultrasound measurements: Comparison of curved-array and linear-array transducers
Published in Journal of rehabilitation research and development (01-01-2014)“…Muscle-mass loss augers increased morbidity and mortality in critically ill patients. Muscle-mass loss can be assessed by wide linear-array ultrasound…”
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