Search Results - "LAGERSTRÖM, M C."

The Ancestry of the Prolactin-Releasing Hormone Precursor by LAGERSTRÖM, M C., FREDRIKSSON, R, BJARNADOTTIR, T K., SCHIÖTH, H B.

“…: The prolactin‐releasing hormone (PRLH) is implicated in food intake and is expressed in several parts of the mammalian brain. The origin of the peptide…”
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Origin of the prolactin-releasing hormone (PRLH) receptors: Evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution by Lagerström, Malin C., Fredriksson, Robert, Bjarnadóttir, Thóra K., Fridmanis, Davids, Holmquist, Tomas, Andersson, Jan, Yan, Yi-Lin, Raudsepp, Terje, Zoorob, Rima, Kukkonen, Jyrki P., Lundin, Lars-Gustav, Klovins, Janis, Chowdhary, Bhanu P., Postlethwait, John H., Schiöth, Helgi B.

“…We present seven new vertebrate homologs of the prolactin-releasing hormone receptor (PRLHR) and show that these are found as two separate subtypes, PRLHR1 and…”
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The human and mouse repertoire of the adhesion family of G-protein-coupled receptors by Bjarnadóttir, Thóra K., Fredriksson, Robert, Höglund, Pär J., Gloriam, David E., Lagerström, Malin C., Schiöth, Helgi B.

“…The adhesion G-protein-coupled receptors (GPCRs) (also termed LN-7TM or EGF-7TM receptors) are membrane-bound proteins with long N-termini containing multiple…”
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Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes by Haitina, Tatjana, Klovins, Janis, Andersson, Jan, Fredriksson, Robert, Lagerström, Malin C, Larhammar, Dan, Larson, Earl T, Schiöth, Helgi B

“…The rainbow trout (Oncorhynchus mykiss) is one of the most widely used fish species in aquaculture and physiological research. In the present paper, we report…”
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Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types by Häring, Martin, Zeisel, Amit, Hochgerner, Hannah, Rinwa, Puneet, Jakobsson, Jon E. T., Lönnerberg, Peter, La Manno, Gioele, Sharma, Nilesh, Borgius, Lotta, Kiehn, Ole, Lagerström, Malin C., Linnarsson, Sten, Ernfors, Patrik

“…The dorsal horn of the spinal cord is critical to processing distinct modalities of noxious and innocuous sensation, but little is known of the neuronal…”
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The Secretin GPCRs Descended from the Family of Adhesion GPCRs by Nordström, Karl J. V., Lagerström, Malin C., Wallér, Linn M. J., Fredriksson, Robert, Schiöth, Helgi B.

“…The Adhesion G-protein-coupled receptors (GPCRs) are the most complex gene family among GPCRs with large genomic size, multiple introns, and a fascinating…”
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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints by Fredriksson, Robert, Lagerström, Malin C, Lundin, Lars-Gustav, Schiöth, Helgi B

“…The superfamily of G-protein-coupled receptors (GPCRs) is very diverse in structure and function and its members are among the most pursued targets for drug…”
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Adult spinal Dmrt3 neurons receive direct somatosensory inputs from ipsi‐ and contralateral primary afferents and from brainstem motor nuclei by Vieillard, Jennifer, Franck, Marina C. M., Hartung, Sunniva, Jakobsson, Jon E. T., Ceder, Mikaela M., Welsh, Robert E., Lagerström, Malin C., Kullander, Klas

“…In the spinal cord, sensory‐motor circuits controlling motor activity are situated in the dorso–ventral interface. The neurons identified by the expression of…”
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Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives by Fredriksson, Robert, Höglund, Pär J, Gloriam, David E.I, Lagerström, Malin C, Schiöth, Helgi B

“…We report seven new members of the superfamily of human G protein-coupled receptors (GPCRs) found by searches in the human genome databases, termed GPR100,…”
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Restricted Cortical and Amygdaloid Removal of Vesicular Glutamate Transporter 2 in Preadolescent Mice Impacts Dopaminergic Activity and Neuronal Circuitry of Higher Brain Function by Wallen-Mackenzie, Asa, Nordenankar, Karin, Fejgin, Kim, Lagerstrom, Malin C, Emilsson, Lina, Fredriksson, Robert, Wass, Caroline, Andersson, Daniel, Egecioglu, Emil, Andersson, My, Strandberg, Joakim, Lindhe, Orjan, Schioth, Helgi B, Chergui, Karima, Hanse, Eric, Langstrom, Bengt, Fredriksson, Anders, Svensson, Lennart, Roman, Erika, Kullander, Klas

“…A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits…”
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There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini by Fredriksson, Robert, Gloriam, David E.I., Höglund, Pär J., Lagerström, Malin C., Schiöth, Helgi B.

“…We report six novel members of the superfamily of human G-protein coupled receptors (GPCRs) found by searches in the human genome databases, termed GPR123,…”
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Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions by Fredriksson, Robert, Lagerström, Malin C, Höglund, Pär J, Schiöth, Helgi B

“…We report eight novel members of the superfamily of human G protein-coupled receptors (GPCRs) found by searches in the human genome databases, termed GPR97,…”
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Expansion of the Superfamily of G-Protein-Coupled Receptors in Chordates by FREDRIKSSON, ROBERT, LAGERSTRÖM, MALIN C., SCHIÖTH, HELGI B.

“…: We have used sequence hidden Markov models to identify and classify all G‐protein‐coupled receptors (GPCRs) from 13 eukaryotic genomes. We found that the 5…”
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High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3 by Lagerström, Malin C., Klovins, Janis, Fredriksson, Robert, Fridmanis, Davids, Haitina, Tatjana, Ling, Maria K., Berglund, Magnus M., Schiöth, Helgi B.

“…We created a molecular model of the human melanocortin 4 receptor (MC4R) and introduced a series of His residues into the receptor protein to form metal ion…”
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Functional Role, Structure, and Evolution of the Melanocortin-4 Receptor by SCHIÖTH, HELGI B., LAGERSTRÖM, MALIN C., WATANOBE, HAJIME, JONSSON, LOGI, VERGONI, ANNA VALERIA, RINGHOLM, ANETA, SKARPHEDINSSON, JON O., SKULADOTTIR, GUDRUN V., KLOVINS, JANIS, FREDRIKSSON, ROBERT

“…: The melanocortin (MC)‐4 receptor participates in regulating body weight homeostasis. We demonstrated early that acute blockage of the MC‐4 receptor increases…”
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Association of feather colour with constitutively active melanocortin 1 receptors in chicken by Ling, Maria K., Lagerström, Malin C., Fredriksson, Robert, Okimoto, Ronald, Mundy, Nicholas I., Takeuchi, Sakae, Schiöth, Helgi B.

“…Seven alleles of the chicken melanocortin (MC) 1 receptor were cloned into expression vectors, expressed in mammalian cells and pharmacologically…”
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