Search Results - "LAFOLIE, P"

Ethical aspects of registry-based research in the Nordic countries by Ludvigsson, Jonas F, Håberg, Siri E, Knudsen, Gun Peggy, Lafolie, Pierre, Zoega, Helga, Sarkkola, Catharina, von Kraemer, Stephanie, Weiderpass, Elisabete, Nørgaard, Mette

“…National health care registries in the Nordic countries share many attributes, but different legal and ethical frameworks represent a challenge to promoting…”
Get full text

Nitric oxide as a marker for evaluation of treatment effect of cyclosporine A in patients with bladder pain syndrome/interstitial cystitis type 3C by Ehrén, Ingrid, Hallén Grufman, Katarina, Vrba, Margit, Sundelin, Runa, Lafolie, Pierre

“…Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic inflammatory disease and to date few treatments or tools for investigating the activity of…”
Get more information

Gastroduodenal Tolerance of 75 mg Clopidogrel versus 325 mg Aspirin in Healthy Volunteers: A Gastroscopic Study by Fork, F T, Lafolie, P, Tóth, E, Lindgärde, F

“…Background: Clopidogrel is a new antiplatelet agent that offers increased protection over aspirin in preventing vascular ischaemic events in patients with…”
Get full text

The addition of tramadol to morphine via patient-controlled analgesia does not lead to better post-operative pain relief after total knee arthroplasty by Stiller, C.-O., Lundblad, H., Weidenhielm, L., Tullberg, T., Grantinger, B., Lafolie, P., Jansson, K.-Å.

“…Background:  Tramadol is used as an analgesic in post‐operative pain treatment. Intravenous tramadol is often combined with morphine to achieve better pain…”
Get full text

Pharmacokinetics after an intravenous single dose of the opioid ketobemidone in children by LUNDEBERG, S., STEPHANSON, N., LAFOLIE, P., OLSSON, G. L., STILLER, C.-O., EKSBORG, S.

“…Background: Ketobemidone is often used as an alternative to morphine in children in the Scandinavian countries. The aim of this clinical trial was to explore…”
Get full text

Importance of creatinine analyses of urine when screening for abused drugs by Lafolie, P, Beck, O, Blennow, G, Boréus, L, Borg, S, Elwin, C E, Karlsson, L, Odelius, G, Hjemdahl, P

“…We report here a simple method involving urine creatine measurements for testing authenticity and reducing false-negative results in urine testing for drugs of…”
Get more information

Subjective and objective symptoms in relation to plasma methadone concentration in methadone patients by HILTUNEN, A. J, LAFOLIE, P, MARTEL, J, OTTOSSON, E.-C, BOREUS, L. O, BECK, O, BORG, S, HJEMDAHL, P

“…Two rating scales, which were originally developed for measurements of objective and subjective signs of opiate withdrawal, were used to evaluate potential…”
Get full text

Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells by Karim, Hazhar, Ghalali, Aram, Lafolie, Pierre, Vitols, Sigurd, Fotoohi, Alan K.

“…•We knocked down the TPMT gene using specifically designed siRNA in MOLT4 cells.•Our results show increased sensitivity of the cells to 6-TG, as compared to…”
Get full text

Urine and Plasma Pharmacokinetics of Codeine in Healthy Volunteers: Implications for Drugs-of-Abuse Testing by Lafolie, Pierre, Beck, Olof, Lin, Zhen, Albertioni, Freidoun, Boréus, Lars

“…Thirteen healthy volunteers participating in an open and randomized study received two single doses (25 and 50 rag) of codeine orally two weeks apart. Urine…”
Get full text

Using relation between urinary cannabinoid and creatinine excretions to improve monitoring of abuser adherence to abstinence by Lafolie, P, Beck, O, Hjemdahl, P, Borg, S

Get more information

Evaluation of safety and efficacy as an adjuvant for the chitosan-based vaccine delivery vehicle ViscoGel in a single-blind randomised Phase I/IIa clinical trial by Neimert-Andersson, Theresa, Binnmyr, Jonas, Enoksson, Mattias, Langebäck, Joakim, Zettergren, Louise, Hällgren, Anne-Charlotte, Franzén, Henry, Lind Enoksson, Sara, Lafolie, Pierre, Lindberg, Alf, Al-Tawil, Nabil, Andersson, Mats, Singer, Peter, Grönlund, Hans, Gafvelin, Guro

“…Highlights • ViscoGel is safe and well tolerated after one intramuscular injection in man. • ViscoGel impacts on the cell-mediated response to the model…”
Get full text

Pronounced Interindividual But Not Intraindividual Variation in Tamoxifen and Metabolite Levels in Plasma During Adjuvant Treatment of Women With Early Breast Cancer by Fotoohi, Alan K, Karim, Hazhar, Lafolie, Pierre, Pohanka, Anton, Östervall, Jennie, Hatschek, Thomas, Vitols, Sigurd

“…Tamoxifen is still an important antihormonal treatment option for patients with breast cancer and estrogen receptor-positive tumors. More than 20% of patients…”
Get full text

Deficient performance of drugs of abuse testing in Sweden: an external control study by Lafolie, P, Beck, O

“…Testing for drugs of abuse in urine is usually performed in two steps; after initial screening positive findings are confirmed with specific chromatographic…”
Get more information

Modification of commercial assay kits is justified by Beck, O, Lafolie, P, Hjemdahl, P

Get more information

LifeTrain: towards a European framework for continuing professional development in biomedical sciences by Hardman, Mike, Brooksbank, Cath, Johnson, Claire, Janko, Christa, See, Wolf, Lafolie, Pierre, Klech, Heinrich, Verpillat, Patrice, Lindén, Hans

“…Successful biomedical scientists learn throughout their careers. The LifeTrain project aims to optimize investments in learning to support the development of…”
Get full text

Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled study by Kupcinskas, Limas, Lafolie, Pierre, Lignell, Åke, Kiudelis, Gediminas, Jonaitis, Laimas, Adamonis, Kestutis, Andersen, Leif Percival, Wadström, Torkel

“…The aim of this study was to evaluate the efficacy of the natural antioxidant astaxanthin in functional dyspepsia in different doses and compared with placebo…”
Get full text

More symptoms with sialic receptor‐positive adenovirus in epidemic keratoconjunctivitis by Dahl, Madeleine, Gerhardsson, Erik, Lafolie, Pierre, Allard, Annika, Laurell, Carl‐Gustaf

Get full text

Intraindividual variation in 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute lymphoblastic leukaemia by LAFOLIE, P, HAYDER, S, BJORK, O, PETERSON, C

“…Intraindividual variation in 6-mercaptopurine (6-MP) kinetics has been little studied. It has now been examined in 18 children with acute lymphoblastic…”
Get full text

Ethical review of research in the grey area. The Ethical Review Act should be widened and case management more efficient by Lafolie, Pierre, Agahi, Neda

“…The present legal definition of the term research creates problems with what can be considered for ethical vetting by the Research Ethical Review Board. The…”
Get more information

The course of biological parameters and 6-mercaptopurine pharmacokinetics during maintenance treatment of children with acute lymphoblastic leukaemia by Hayder, S, Björk, O, Lafolie, P

“…Twenty patients on maintenance therapy (MT) for acute lymphoblastic leukaemia (ALL) with oral 6-mercaptopurine (6-MP) and methotrexate (MTX) were studied…”
Get more information