Search Results - "LAEDERMANN, Cedric J"

Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes by Laedermann, Cedric J, Abriel, Hugues, Decosterd, Isabelle

“…In the peripheral sensory nervous system the neuronal expression of voltage-gated sodium channels (Navs) is very important for the transmission of nociceptive…”
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Rufinamide Attenuates Mechanical Allodynia in a Model of Neuropathic Pain in the Mouse and Stabilizes Voltage-gated Sodium Channel Inactivated State by SUTER, Marc R, KIRSCHMANN, Guylène, LAEDERMANN, Cedric J, ABRIEL, Hugues, DECOSTERD, Isabelle

“…Voltage-gated sodium channels dysregulation is important for hyperexcitability leading to pain persistence. Sodium channel blockers currently used to treat…”
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Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain by Laedermann, Cédric J, Cachemaille, Matthieu, Kirschmann, Guylène, Pertin, Marie, Gosselin, Romain-Daniel, Chang, Isabelle, Albesa, Maxime, Towne, Chris, Schneider, Bernard L, Kellenberger, Stephan, Abriel, Hugues, Decosterd, Isabelle

“…Peripheral neuropathic pain is a disabling condition resulting from nerve injury. It is characterized by the dysregulation of voltage-gated sodium channels…”
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Voltage-Gated Sodium Channel Expression in Mouse DRG after SNI Leads to Re-Evaluation of Projections of Injured Fibers by Laedermann, Cédric J, Pertin, Marie, Suter, Marc R, Decosterd, Isabelle

“…Background: Dysregulation of voltage-gated sodium channels (Navs) is believed to play a major role in nerve fiber hyperexcitability associated with neuropathic…”
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The Antidiabetic Drug Metformin Regulates Voltage-Gated Sodium Channel NaV1.7 via the Ubiquitin-Ligase NEDD4-2 by Deftu, Alexandru-Florian, Chu Sin Chung, Paul, Laedermann, Cédric J, Gillet, Ludovic, Pertin, Marie, Kirschmann, Guylène, Decosterd, Isabelle

“…The antidiabetic drug metformin has been shown to reduce pain hypersensitivity in preclinical models of chronic pain and in neuropathic pain in humans…”
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Ubiquitylation of voltage-gated sodium channels by Laedermann, Cédric J, Decosterd, Isabelle, Abriel, Hugues

“…Ion channel proteins are regulated by different types of posttranslational modifications. The focus of this review is the regulation of voltage-gated sodium…”
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p.L1612P, a Novel Voltage-gated Sodium Channel Nav1.7 Mutation Inducing a Cold Sensitive Paroxysmal Extreme Pain Disorder by Suter, Marc R, Bhuiyan, Zahurul A, Laedermann, Cédric J, Kuntzer, Thierry, Schaller, Muriel, Stauffacher, Maurice W, Roulet, Eliane, Abriel, Hugues, Decosterd, Isabelle, Wider, Christian

“…BACKGROUND:Mutations in the SCN9A gene cause chronic pain and pain insensitivity syndromes. We aimed to study clinical, genetic, and electrophysiological…”
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β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells by Laedermann, Cédric J, Syam, Ninda, Pertin, Marie, Decosterd, Isabelle, Abriel, Hugues

“…Voltage-gated sodium channels (Navs) are glycoproteins composed of a pore-forming α-subunit and associated β-subunits that regulate Nav α-subunit plasma…”
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The Antidiabetic Drug Metformin Regulates Voltage-Gated Sodium Channel Na V 1.7 via the Ubiquitin-Ligase NEDD4-2 by Deftu, Alexandru-Florian, Chu Sin Chung, Paul, Laedermann, Cédric J, Gillet, Ludovic, Pertin, Marie, Kirschmann, Guylène, Decosterd, Isabelle

“…The antidiabetic drug metformin has been shown to reduce pain hypersensitivity in preclinical models of chronic pain and in neuropathic pain in humans…”
Get full text