Search Results - "LADEDA, Virginia"
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Glypican-3 expression is silenced in human breast cancer
Published in Oncogene (01-11-2001)“…Glypican-3 (GPC3) is a membrane-bound heparan sulfate proteoglycan that is mutated in the Simpson-Golabi-Behmel syndrome. This is an X-linked condition…”
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2
CD44 expression in human gliomas
Published in Journal of surgical oncology (01-01-2002)“…Background and Objectives Glioma invasiveness involves the attachment of tumor cells to the brain extracellular matrix, rich in hyaluronic acid (HA). CD44, the…”
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Function and Expression of CD44 during Spreading, Migration, and Invasion of Murine Carcinoma Cells
Published in Experimental cell research (01-08-1998)“…The cell surface glycoprotein CD44 is proposed as a main participant in cell adhesion and migration. We studied the function, expression, and distribution of…”
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Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells
Published in Oncogene (25-04-2002)Get full text
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Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells
Published in Oncogene (25-04-2002)“…Acquisition of resistance to anoikis (detachment-induced apoptosis) is considered to be a requirement for transformed intestinal epithelial cells to invade…”
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Verapamil inhibits tumor protease production, local invasion and metastasis development in murine carcinoma cells
Published in International journal of cancer (09-12-1998)“…The invasion and metastasis process involves degradation of the extracellular matrix mediated by tumor‐ and host‐produced proteolytic enzymes. The main enzymes…”
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Increased Bcl-xLexpression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells
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8
Apoptotic cell death in mammary adenocarcinoma cells is prevented by soluble factors present in the target organ of metastasis
Published in Breast cancer research and treatment (01-09-2001)“…Target organ of metastasis determines the fate of metastasis. The soluble factors released from one or more cell types in the new stroma may influence growth…”
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Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model
Published in Breast cancer research and treatment (01-01-1996)“…Urokinase-type plasminogen activator (uPA) initiates an extracellular proteolytic cascade with which invasive cells eliminate barriers to movement. We have…”
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RalA Mediates v-Src, v-Ras, and v-Raf Regulation of CD44 and Fibronectin Expression in NIH3T3 Fibroblasts
Published in Biochemical and biophysical research communications (18-05-2001)“…Oncogenic transformation of fibroblasts by v-Src and v-Ras is often associated with downregulation of fibronectin (FN) and increased expression of CD44, a…”
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Combined treatment with verapamil, a calcium channel blocker, and B428, a synthetic uPA inhibitor, impairs the metastatic ability of a murine mammary carcinoma
Published in Oncology reports (01-05-2003)“…Urokinase plasminogen activator (uPA) and metalloproteinases (MMP) play key roles in invasion and metastasis, degrading extracellular matrix compounds and…”
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Characterization of F3II, a sarcomatoid mammary carcinoma cell line originated from a clonal subpopulation of a mouse adenocarcinoma
Published in Journal of surgical oncology (01-08-1996)“…We characterized a new mammary tumor cell line, F3II, previously established in vitro from a clonal subpopulation of the BALB/c transplantable mammary…”
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13
Expression of CD44s and CD44 splice variants in human melanoma
Published in Oncology reports (01-01-2002)“…The ability of tumor cells to adhere and detach from extracellular matrix and endothelial cells, is a crucial step in the metastatic process and may alter the…”
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CD44 expression in human gliomas. Commentary
Published in Journal of surgical oncology (2002)Get full text
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