Search Results - "LACKNER, Edith"

Single- and Repeated-Dose Pharmacokinetics of Ceftaroline in Plasma and Soft Tissues of Healthy Volunteers for Two Different Dosing Regimens of Ceftaroline Fosamil by Matzneller, Peter, Lackner, Edith, Lagler, Heimo, Wulkersdorfer, Beatrix, Österreicher, Zoe, Zeitlinger, Markus

“…Ceftaroline fosamil (CPT-F) is currently approved for use for the treatment of complicated skin and soft tissue infections and community-acquired pneumonia at…”
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Effects of Olanzapine and Ziprasidone on Glucose Tolerance in Healthy Volunteers by SACHER, Julia, MOSSAHEB, Nilufar, SPINDELEGGER, Christoph, KLEIN, Nikolas, GEISS-GRANADIA, Thomas, SAUERMANN, Robert, LACKNER, Edith, JOUKHADAR, Christian, FTULLER, Markus, KASPER, Siegfried

“…Atypical antipsychotics have been linked to a higher risk for glucose intolerance, and consequentially the development of type 2 diabetes mellitus (DM2). We…”
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A new topical formulation enhances relative diclofenac bioavailability in healthy male subjects by Brunner, Martin, Davies, David, Martin, Wolfgang, Leuratti, Chiara, Lackner, Edith, Müller, Markus

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Therapy with topical non‐steroidal anti‐inflammatory drugs (NSAIDs) relies on the ability of the active drug to…”
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Phase I Study to Assess Safety of Laser-Assisted Topical Administration of an Anti-TNF Biologic in Patients With Chronic Plaque-Type Psoriasis by Bauer, Martin, Lackner, Edith, Matzneller, Peter, Al Jalali, Valentin, Pajenda, Sahra, Ling, Vincent, Böhler, Christof, Braun, Werner, Braun, Reinhard, Boesch, Maximilian, Brunner, Patrick M., Zeitlinger, Markus

“…Ablative fractional laser treatment facilitates epidermal drug delivery, which might be an interesting option to increase the topical efficacy of biological…”
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Iontophoresis driven concentrations of topically administered diclofenac in skeletal muscle and blood of healthy subjects by Crevenna, Richard, Burian, Angela, Oesterreicher, Zoe, Lackner, Edith, Jäger, Walter, Rezcicek, Gottfried, Keilani, Mohammad, Zeitlinger, Markus

“…Purpose The present open single-centre, descriptive and comparative pharmacokinetic study aimed to investigate the efficacy of iontophoresis to enhance…”
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Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans by Stohlawetz, Petra Jilma, Dzirlo, Larisa, Hergovich, Nicole, Lackner, Edith, Mensik, Christa, Eichler, Hans Georg, Kabrna, Eva, Geissler, Klaus, Jilma, Bernd

“…A recent study in dogs suggested that erythropoietin (EPO) not only promotes the synthesis of increased numbers of reticulated platelets but that these newly…”
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Magnetic Resonance Imaging Analysis of the Spread of Local Anesthetic Solution after Ultrasound-guided Lateral Thoracic Paravertebral Blockade by Marhofer, Daniela, Marhofer, Peter, Kettner, Stephan C., Fleischmann, Edith, Prayer, Daniela, Schernthaner, Melanie, Lackner, Edith, Willschke, Harald, Schwetz, Pascal, Zeitlinger, Markus

“…Abstract Background: This study was designed to examine the spread of local anesthetic (LA) via magnetic resonance imaging after a standardized…”
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Penetration of Moxifloxacin into Healthy and Inflamed Subcutaneous Adipose Tissues in Humans by JOUKHADAR, Christian, STASS, Heino, MULLER-ZELLENBERG, Ulrike, LACKNER, Edith, KOVAR, Florian, MINAR, Erich, MÜLLER, Markus

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Penetration of Moxifloxacin into Peripheral Compartments in Humans by Müller, M, Stass, H, Brunner, M, Möller, J G, Lackner, E, Eichler, H G

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Concentrations of Gemifloxacin at the Target Site in Healthy Volunteers after a Single Oral Dose by ISLINGER, Florian, BOUW, Rene, STAHL, Mathias, LACKNER, Edith, ZELENY, Petra, BRUNNER, Martin, MÜLLER, Markus, EICHLER, Hans Georg, JOUKHADAR, Christian

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Distribution and Antimicrobial Activity of Ciprofloxacin in Human Soft Tissues by BRUNNER, M, HOLLENSTEIN, U, DELACHER, S, JÄGER, D, SCHMID, R, LACKNER, E, GEORGOPOULOS, A, EICHLER, H. G, MÜLLER, M

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High voriconazole target-site exposure after approved sequence dosing due to nonlinear pharmacokinetics assessed by long-term microdialysis by Kirbs, Claudia, Kluwe, Franziska, Drescher, Franziska, Lackner, Edith, Matzneller, Peter, Weiss, Johanna, Zeitlinger, Markus, Kloft, Charlotte

“…Voriconazole, a broad-spectrum antifungal drug used to prevent and treat invasive fungal infections, shows complex pharmacokinetics and is primarily…”
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Diclofenac in vitro microdialysis study comparing different experimental set‐ups to improve quantitative recovery by Jorda, Anselm, Armogida, Marianna, Lackner, Edith, Saikumar, Sivasankari, Sucharski, Filip, Weber, Maria, Zeitlinger, Markus

“…Several studies investigated diclofenac tissue concentrations using microdialysis (MD). However, thorough evaluations of the optimal MD set‐up for diclofenac…”
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Lack of dermal penetration of topically applied gentamicin as pharmacokinetic evidence indicating insufficient efficacy by Oesterreicher, Zoe, Lackner, Edith, Jäger, Walter, Höferl, Martina, Zeitlinger, Markus

“…Treatment of skin and superficial soft tissue infections with topically applied antibiotics is a controversial topic, because only few clinical studies exist…”
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Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU by Wulkersdorfer, Beatrix, Bergmann, Felix, Amann, Lisa, Fochtmann-Frana, Alexandra, Al Jalali, Valentin, Kurdina, Elizaveta, Lackner, Edith, Wicha, Sebastian G, Dorn, Christoph, Schäfer, Bruno, Ihra, Gerald, Rath, Thomas, Radtke, Christine, Zeitlinger, Markus

“…Abstract Background Pathophysiological changes in severely burned patients alter the pharmacokinetics (PK) of anti-infective agents, potentially leading to…”
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Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination by Sanz-Codina, Maria, Wicha, Sebastian G, Wulkersdorfer, Beatrix, Al Jalali, Valentin, Van Os, Wisse, Vossen, Matthias G, Bauer, Martin, Lackner, Edith, Dorn, Christoph, Zeitlinger, Markus

“…High protein binding (PB) of antibiotics has an impact on their antimicrobial activity. It has been questioned whether in vitro PB determination can capture…”
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Feasibility of microdialysis for determination of protein binding and target site pharmacokinetics of colistin in vivo by Matzneller, Peter, Gobin, Patrice, Lackner, Edith, Zeitlinger, Markus

“…Tissue pharmacokinetics and plasma protein binding of colistin have not been described in humans in vivo. Colistin concentrations in plasma, muscle, and…”
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Tissue pharmacokinetics of telavancin in healthy volunteers: a microdialysis study by Matzneller, Peter, Österreicher, Zoe, Reiter, Birgit, Lackner, Edith, Stimpfl, Thomas, Zeitlinger, Markus

“…Telavancin is a novel lipoglycoprotein antibiotic with MRSA activity. To date, tissue pharmacokinetics (PK) and plasma protein binding of the drug are…”
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Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers by Sanz-Codina, Maria, van Os, Wisse, Pham, Anh Duc, Jorda, Anselm, Wölf-Duchek, Michael, Bergmann, Felix, Lackner, Edith, Lier, Constantin, van Hasselt, J G Coen, Minichmayr, Iris K, Dorn, Christoph, Zeitlinger, Markus, Al Jalali, Valentin

“…Cefiderocol may potentially be used to treat skin and soft tissue infections (SSTIs). However, the pharmacokinetics of cefiderocol in human soft tissues have…”
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Comparison of pharmacokinetics and stability of generics of cefepime, linezolid and piperacillin/tazobactam with their respective originator drugs: an intravenous bioequivalence study in healthy volunteers by Bergmann, Felix, Wulkersdorfer, Beatrix, Oesterreicher, Zoe, Bauer, Martin, al Jalali, Valentin, Nussbaumer-Pröll, Alina, Wölfl-Duchek, Michael, Jorda, Anselm, Lackner, Edith, Reiter, Birgit, Stimpfl, Thomas, Ballarini, Nicolas, König, Franz, Zeitlinger, Markus

“…Abstract Objectives The efficacy and quality of generic antibacterial drug formulations are often questioned by both healthcare specialists and patients…”
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