Search Results - "LACAZE, Paul"

Ethical and practical implications of returning genetic research results: two Australian case studies by Tiller, Jane, Trainer, Alison H, Campbell, Ian, Lacaze, Paul A

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Monitoring the genetic testing and life insurance moratorium in Australia: a national research project by Tiller, Jane, Winship, Ingrid, Otlowski, Margaret FA, Lacaze, Paul A

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Blood DNA methylation as a potential biomarker of dementia: A systematic review by Fransquet, Peter D., Lacaze, Paul, Saffery, Richard, McNeil, John, Woods, Robyn, Ryan, Joanne

“…Dementia is a major public health issue with rising prevalence rates, but many individuals remain undiagnosed. Accurate and timely diagnosis is key for the…”
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The Australian moratorium on genetics and life insurance: evaluating policy compared to Parliamentary recommendations regarding genetic discrimination by Tiller, Jane, Lacaze, Paul, Otlowski, Margaret

“…Objectives and importance of study: Genetic discrimination is a health policy issue of international concern to clinicians, patients, researchers, and policy…”
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Population DNA screening for medically actionable disease risk in adults by Lacaze, Paul A, Tiller, Jane, Winship, Ingrid, Lacaze, Paul, Tiller, Jane, Winship, Ingrid, Brotchie, Adam, McNeil, John, Zalcberg, John, Thomas, David, Milne, Roger, James, Paul, Delatycki, Martin, Young, Mary‐Anne, Nowak, Kristen, Nguyen‐Dumont, Tu, Southey, Melissa, Ademi, Zanfina, Bruinsma, Fiona, Riaz, Moeen, Terrill, Bronwyn, Kirk, Judy, Tucker, Kathy, Andrews, Lesley, Pachter, Nicholas, Susman, Rachel, Poplawski, Nicola, Wallis, Matthew, Watts, Gerald, Nicholls, Steve, Macrae, Finlay, Sturm, Amy, Green, Robert, Ahern, Susannah, Revote, Jerico, Von Saldern, Simon, Powell, Sarah, Rice, Toni

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Current state of rare disease registries and databases in Australia: a scoping review by Ruseckaite, Rasa, Mudunna, Chethana, Caruso, Marisa, Helwani, Falak, Millis, Nicole, Lacaze, Paul, Ahern, Susannah

“…Rare diseases (RDs) affect approximately 8% of all people or > 400 million people globally. The Australian Government's National Strategic Action Plan for Rare…”
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The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response by Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter

“…Recent studies suggest that the sterol metabolic network participates in the interferon (IFN) antiviral response. However, the molecular mechanisms linking IFN…”
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Phenotypic Heterogeneity in Dementia: A Challenge for Epidemiology and Biomarker Studies by Ryan, Joanne, Fransquet, Peter, Wrigglesworth, Jo, Lacaze, Paul

“…Dementia can result from a number of distinct diseases with differing etiology and pathophysiology. Even within the same disease, there is considerable…”
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Genetic discrimination by Australian insurance companies: a survey of consumer experiences by Tiller, Jane, Morris, Susan, Rice, Toni, Barter, Krystal, Riaz, Moeen, Keogh, Louise, Delatycki, Martin B, Otlowski, Margaret, Lacaze, Paul

“…We report previously undocumented evidence of genetic discrimination by Australian insurance companies, obtained through direct consumer reports. We surveyed…”
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Loss of Y and clonal hematopoiesis in blood—two sides of the same coin? by Ljungström, Viktor, Mattisson, Jonas, Halvardson, Jonatan, Pandzic, Tatjana, Davies, Hanna, Rychlicka-Buniowska, Edyta, Danielsson, Marcus, Lacaze, Paul, Cavelier, Lucia, Dumanski, Jan P., Baliakas, Panagiotis, Forsberg, Lars A.

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Implementation of public health genomics in Pakistan by Riaz, Moeen, Tiller, Jane, Ajmal, Muhammad, Azam, Maleeha, Qamar, Raheel, Lacaze, Paul

“…There has been considerable recent progress in the implementation of public health genomics policy throughout the developed world. However, in the developing…”
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Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis by Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A, Watterson, Steven, Shui, Guanghou, Lacaze, Paul, Khondoker, Mizanur, Dickinson, Paul, Sing, Garwin, Rodríguez-Martín, Sara, Phelan, Peter, Forster, Thorsten, Strobl, Birgit, Müller, Matthias, Riemersma, Rudolph, Osborne, Timothy, Wenk, Markus R, Angulo, Ana, Ghazal, Peter

“…Little is known about the protective role of inflammatory processes in modulating lipid metabolism in infection. Here we report an intimate link between the…”
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Public Involvement in Global Genomics Research: A Scoping Review by Nunn, Jack S, Tiller, Jane, Fransquet, Peter, Lacaze, Paul

“…Public involvement in research occurs when the public, patients, or research participants are actively contributing to the research process. Public involvement…”
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Regulation of Internet-based Genetic Testing: Challenges for Australia and Other Jurisdictions by Tiller, Jane, Lacaze, Paul

“…The Internet currently enables unprecedented ease of access for direct-to-consumer (DTC) genetic testing, with saliva collection kits posted directly to…”
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Should Australia Ban the Use of Genetic Test Results in Life Insurance? by Tiller, Jane, Otlowski, Margaret, Lacaze, Paul

“…Under current Australian regulation, life insurance companies can require applicants to disclose all genetic test results, including results from research or…”
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Genetic testing and insurance in Australia by Otlowski, Margaret, Barlow-Stewart, Kristine, Lacaze, Paul, Tiller, Jane

“…Genetic testing offers great benefit for the diagnosis of genetic conditions and to identify and manage risk for conditions such as familial breast cancer…”
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Co-designing genomics research with a large group of donor-conceived siblings by Nunn, Jack S, Crawshaw, Marilyn, Lacaze, Paul

“…Human genomics research is growing rapidly. More effective methods are required for co-design and involving people, especially those sub-populations which are…”
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Future implications of polygenic risk scores for life insurance underwriting by Yanes, Tatiane, Tiller, Jane, Haining, Casey M., Wallingford, Courtney, Otlowski, Margaret, Keogh, Louise, McInerney-Leo, Aideen, Lacaze, Paul

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Study protocol: the Australian genetics and life insurance moratorium—monitoring the effectiveness and response (A-GLIMMER) project by Tiller, Jane, McInerney-Leo, Aideen, Belcher, Andrea, Boughtwood, Tiffany, Gleeson, Penny, Delatycki, Martin, Barlow-Stewart, Kristine, Winship, Ingrid, Otlowski, Margaret, Keogh, Louise, Lacaze, Paul

“…Abstract Background The use of genetic test results in risk-rated insurance is a significant concern internationally, with many countries banning or…”
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Efficacy and safety of avatrombopag in combination with immunosuppressive therapy in treatment-naïve and relapsed/refractory severe aplastic anaemia: protocol for the DIAAMOND-Ava-FIRST and DIAAMOND-Ava-NEXT Bayesian Optimal Phase II trials by McQuilten, Zoe, Heritier, Stephane, Fox, Lucy, Fox, Vanessa, Young, Lauren, Blombery, Piers, Cunningham, Ilona, Curnow, Jennifer, Higgins, Alisa, Hiwase, Devendra K, Filshie, Robin, Firkin, Frank, Lacaze, Paul, Mason, Kylie, Mills, Anthony K, Pepperell, Dominic, Patil, Sushrut, Stevenson, William, Szer, Jeff, Waters, Neil, Wilson, Kate, Ting, Stephen, Wood, Erica

“…IntroductionImmunosuppressive therapy (IST) with antithymocyte globulin (ATG) and ciclosporin is standard of care for patients with severe aplastic anaemia…”
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