Search Results - "LABIDALLE, Serge"

Effects of curcumin and curcumin derivatives on mitochondrial permeability transition pore by Ligeret, Heidi, Barthelemy, Sophie, Zini, Roland, Tillement, Jean-Paul, Labidalle, Serge, Morin, Didier

“…Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) is a natural compound with antiproliferative properties. Recent studies suggest that…”
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Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation by Morin, Didier, Barthélémy, Sophie, Zini, Roland, Labidalle, Serge, Tillement, Jean-Paul

“…Curcumin is a natural compound showing antiproliferative properties. Recent studies suggest that these properties might be due to its ability to induce…”
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Structure–Property Relationships of Trimetazidine Derivatives and Model Compounds as Potential Antioxidants by Ancerewicz, Jacek, Migliavacca, Eugenia, Carrupt, Pierre-Alain, Testa, Bernard, Brée, Françoise, Zini, Roland, Tillement, Jean-Paul, Labidalle, Serge, Guyot, Daniel, Chauvet-Monges, Anne-Marie, Crevat, Aimé, Le Ridant, Alain

“…Twenty-five compounds (trimetazidine derivatives and other compounds, mostly having a free phenolic group) were examined for their radical scavenging and…”
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NO-Mediated Aromatic Nitration during Decomposition of Phenolic S-Nitrosothiols in Non-Aqueous Aerobic Medium by PETIT, Catherine, BERNARDES-GENISSON, Vania, HOFFMANN, Pascal, SOUCHARD, Jean-Pierre, LABIDALLE, Serge

“…Five novel S-nitrosothiol compounds (6-10) derived from L-cysteine were generated in solution and their decomposition rate was followed by UV spectroscopy. In…”
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Protective effects of the lipophilic redox conjugate tocopheryl succinyl-ethyl ferulate on HIV replication by Edeas, Marvin A, Claise, Catherine, Vergnes, Laurent, Yacine Khalfoun, Barthelemy, Sophie, Labidalle, Serge, Lindenbaum, Albert

“…Previously, we demonstrated that ferulate ethyl and tocopherol reduced HIV replication. In this study, we investigate whether the conjugation of both compounds…”
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SYNTHESIS AND CHARACTERIZATION OF NEW AROMATIC THIONITRITES by Petit, Catherine, Hoffmann, Pascal, Souchard, Jean-Pierre, Labidalle, Serge

“…Thionitrites (S-nitrosothiols) play an essential biological role as nitric oxide (NO . ) carriers. Here, we present the synthesis. the characterization and the…”
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Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems by Gafner, Stefan, Lee, Sang-Kook, Cuendet, Muriel, Barthélémy, Sophie, Vergnes, Laurent, Labidalle, Serge, Mehta, Rajendra G., Boone, Charles W., Pezzuto, John M.

“…Curcumin ( 1) and 22 curcumin analogs have been evaluated in cancer chemoprevention models. The substitution pattern on the aromatic moiety proved to be…”
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Fluoride curcumin derivatives: new mitochondrial uncoupling agents by Ligeret, Heidi, Barthélémy, Sophie, Bouchard Doulakas, Géraldine, Carrupt, Pierre-Alain, Tillement, Jean-Paul, Labidalle, Serge, Morin, Didier

“…The mitochondrial effects of two fluoride curcumin derivatives were studied. They induced the collapse of mitochondrial membrane potential (Δψ), increased…”
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[ 3H]BHDP as a novel and selective ligand for σ1 receptors in liver mitochondria and brain synaptosomes of the rat by Klouz, Anis, Tillement, Jean-Paul, Boussard, Marie-Françoise, Wierzbicki, Michel, Berezowski, Vincent, Cecchelli, Roméo, Labidalle, Serge, Onténiente, Brigitte, Morin, Didier

“…The binding profile of [ 3H]BHDP ([ 3H] N-benzyl- N′-(2-hydroxy-3,4-dimethoxybenzyl)-piperazine) was evaluated. [ 3H]BHDP labelled a single class of binding…”
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Dual effect of ebselen on mitochondrial permeability transition by Morin, Didier, Zini, Roland, Ligeret, Heidi, Neckameyer, Wendi, Labidalle, Serge, Tillement, Jean-Paul

“…This study reports an investigation on the effect of the seleno-organic compound ebselen on rat liver mitochondria. We show that low concentrations of ebselen…”
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[3H]BHDP as a novel and selective ligand for sigma1 receptors in liver mitochondria and brain synaptosomes of the rat by Klouz, Anis, Tillement, Jean-Paul, Boussard, Marie-Françoise, Wierzbicki, Michel, Berezowski, Vincent, Cecchelli, Roméo, Labidalle, Serge, Onténiente, Brigitte, Morin, Didier

“…The binding profile of [(3)H]BHDP ([(3)H]N-benzyl-N'-(2-hydroxy-3,4-dimethoxybenzyl)-piperazine) was evaluated. [(3)H]BHDP labelled a single class of binding…”
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[3H]BHDP as a novel and selective ligand for δ1 receptors in liver mitochondria and brain synaptosomes of the rat by Klouz, Anis, Tillement, Jean-Paul, Boussard, Marie-Françoise, Wierzbicki, Michel, Berezowski, Vincent, Cecchelli, Roméo, Labidalle, Serge, Onteniente, Brigitte, Morin, Didier

“…The binding profile of [3H]BHDP [3H]N-benzyl-N'-(2-hydroxy-3,4-dimethoxybenzyl)-piperazine) was evaluated. [3H]BHDP labelled a single class of binding sites…”
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[3H]‐Trimetazidine mitochondrial binding sites: regulation by cations, effect of trimetazidine derivatives and other agents and interaction with an endogenous substance by Morin, Didier, Sapena, Rosa, Elimadi, Aziz, Testa, Bernard, Labidalle, Serge, Le Ridant, Alain, Tillement, Jean‐Paul

“…Trimetazidine, an antiischaemic drug, has been shown to restore impaired mitochondrial functions. Specific binding sites for [3H]‐trimetazidine have been…”
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Synthèse de dérivés imidazopyridiniques et pyridinotriaziniques by Mayrargue, Joëlle, Labidalle, Serge, Randriatsoa, Jean, Moskowitz, Henri, Miocque, Marcel

“…Les propargyl‐1 pyridiniums substitues en 2 par un reste hydroxylamine ou hydrazine se cyclisent par chauffage en imidazopyridiniums. Les analogues substitués…”
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Synthèse de dérivés imidazopyridiniques et pyridinotriaziniques by Mayrargue, Joëlle, Labidalle, Serge, Randriatsoa, Jean, Moskowitz, Henri, Miocque, Marcel

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