Search Results - "LABEUR, C"

female-specific desaturase gene responsible for diene hydrocarbon biosynthesis and courtship behaviour in Drosophila melanogaster by Chertemps, T, Duportets, L, Labeur, C, Ueyama, M, Wicker-Thomas, C

“…Drosophila melanogaster shows sexually dimorphic cuticular hydrocarbons, with monoenes produced in males and dienes produced in females. Here we describe a…”
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Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease by Demeester, N, Castro, G, Desrumaux, C, De Geitere, C, Fruchart, J C, Santens, P, Mulleners, E, Engelborghs, S, De Deyn, P P, Vandekerckhove, J, Rosseneu, M, Labeur, C

“…We investigated the lipoprotein distribution and composition in cerebrospinal fluid (CSF) in a group of patients with Alzheimer's disease (AD) or affected by…”
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Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid β peptides by Demeester, N., Mertens, C., Caster, H., Goethals, M., Vandekerckhove, J., Rosseneu, M., Labeur, C.

“…The Dutch (E22Q) and Flemish (A21G) mutations in the βAPP region of the amyloid precursor protein (APP) are associated with familial forms of Alzheimer…”
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β-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E : Relevance to Alzheimer's disease by PILLOT, T, GOETHALS, M, NAJIB, J, LABEUR, C, LINS, L, CHAMBAZ, J, BRASSEUR, R, VANDEKERCKHOVE, J, ROSSENEU, M

“…Growing evidence indicates the involvement of apolipoprotein E (apoE) in the development of late-onset and sporadic forms of Alzheimer's disease, although its…”
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A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling by Peelman, F., Vinaimont, N., Vanloo, B., Labeur, C., Rosseneu, M., Verhee, A., Verschelde, J‐L., Vanderckove, J., Tavernier, J., Seguret‐Mace, S., Duverger, N., Hutchinson, G.

“…The enzyme cholesterol lecithin acyl transferase (LCAT) shares the Ser/Asp‐Glu/His triad with lipases, esterases and proteases, but the low level of sequence…”
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Decreased postprandial high density lipoprotein cholesterol and apolipoproteins A-I and E in normolipidemic smoking men: relations with lipid transfer proteins and LCAT activities by Mero, N, Van Tol, A, Scheek, L M, Van Gent, T, Labeur, C, Rosseneu, M, Taskinen, M R

“…We have previously reported that normolipidemic smokers are lipid intolerant due to increased responses of triglyceride-rich lipoproteins (TRL) apolipoprotein…”
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Effects of natural mutations in lecithin:cholesterol acyltransferase on the enzyme structure and activity by Peelman, F, Verschelde, J L, Vanloo, B, Ampe, C, Labeur, C, Tavernier, J, Vandekerckhove, J, Rosseneu, M

“…A molecular model was built for human lecithin:cholesterol acyltransferase (LCAT) based upon the structural homology between this enzyme and lipases (Peelman…”
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Apoptosis induced in neuronal cells by C-terminal amyloid beta-fragments is correlated with their aggregation properties in phospholipid membranes by Demeester, N, Baier, G, Enzinger, C, Goethals, M, Vandekerckhove, J, Rosseneu, M, Labeur, C

“…A number of findings suggest that lipophilic monomeric Abeta peptides can interact with the cellular lipid membranes. These interactions can affect the…”
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Characterization of Recombinant Wild Type and Site-Directed Mutations of Apolipoprotein C-III:  Lipid Binding, Displacement of ApoE, and Inhibition of Lipoprotein Lipase by Liu, Haiqun, Talmud, Philippa J, Lins, Laurence, Brasseur, Robert, Olivecrona, Gunilla, Peelman, Frank, Vandekerckhove, Joël, Rosseneu, Maryvonne, Labeur, Christine

“…The physicochemical properties of recombinant wild type and three site-directed mutants of apolipoprotein C-III (apoC-III), designed by molecular modeling to…”
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Immunological assays of apolipoproteins in plasma: methods and instrumentation by Labeur, C, Shepherd, J, Rosseneu, M

“…A number of immunological techniques--radioimmunoassay, enzyme-linked immunosorbent assay (ELISA), electroimmunoassay, radial immunodiffusion, and a variety of…”
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Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr by Liu, H, Labeur, C, Xu, C F, Ferrell, R, Lins, L, Brasseur, R, Rosseneu, M, Weiss, K M, Humphries, S E, Talmud, P J

“…We have identified a G-to-A transition in exon 3 of the APOC3 gene resulting in a novel Ala23Thr apolipoprotein (apo) C-III variant, associated with apoC-III…”
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Enhanced efficiency of a targeted fusogenic peptide by Decout, A., Labeur, C., Goethals, M., Brasseur, R., Vandekerckhove, J., Rosseneu, M.

“…Membrane targeting was investigated as a potential strategy to increase the fusogenic activity of an isolated fusion peptide. This was achieved by coupling the…”
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Effect of mutations of N- and C-terminal charged residues on the activity of LCAT by Peelman, F, Vanloo, B, Verschelde, J L, Labeur, C, Caster, H, Taveirne, J, Verhee, A, Duverger, N, Vandekerckhove, J, Tavernier, J, Rosseneu, M

“…On the basis of structural homology calculations, we previously showed that lecithin:cholesterol acyltransferase (LCAT), like lipases, belongs to the…”
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Comparison of three fatty meals in healthy normolipidaemic men: high post-prandial retinyl ester response to soybean oil by MERO, N, SYVÄNNE, M, ROSSENEU, M, LABEUR, C, HILDEN, H, TASKINEN, M.-R

“…Background Oral fat tolerance tests (FTTs) have been widely used as a tool to investigate post‐prandial lipaemia. However, there is no consensus regarding the…”
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Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT) by Peelman, Frank, Vanloo, Berlinda, Perez-Mendez, Oscar, Decout, Anne, Verschelde, Jean-Luc, Labeur, Christine, Vinaimont, Nicole, Verhee, Annick, Duverger, Nicolas, Brasseur, Robert, Vandekerckhove, Joël, Tavernier, Jan, Rosseneu, Maryvonne

“…Lecithin cholesterol acyltransferase (LCAT) is an interfacial enzyme active on both high-density (HDL) and low-density lipoproteins (LDL). Threading alignments…”
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Plasma lipoprotein(a) values and severity of coronary artery disease in a large population of patients undergoing coronary angiography by Labeur, C, De Bacquer, D, De Backer, G, Vincke, J, Muyldermans, L, Vandekerckhove, Y, Van der Stichele, E, Rosseneu, M

“…To determine possible associations between lipoprotein(a) [Lp(a)] and the severity of coronary artery lesions, we measured lipid, apolipoprotein, and Lp(a) in…”
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Design Of A New Class Of Amphipathic Helical Peptides For The Plasma Apolipoproteins That Promote Cellular Cholesterol Efflux But Do Not Activate Lcat by Labeur, C, Lins, Laurence, Vanloo, B, Baert, J, Brasseur, Robert, Rosseneu, M

“…Amphipathic helical peptides represent the lipid-binding units of the soluble plasma apolipoproteins. Several synthetic peptide analogues have been designed to…”
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Contribution of the hydrophobicity gradient to the secondary structure and activity of fusogenic peptides by Decout, A, Labeur, C, Vanloo, B, Goethals, M, Vandekerckhove, J, Brasseur, R, Rosseneu, M

“…Fusogenic peptides belong to a class of helical amphipathic peptides characterized by a hydrophobicity gradient along the long helical axis. According to the…”
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Abetalipoproteinemia with an ApoB-100-lipoprotein(a) glycoprotein complex in plasma. Indication for an assembly defect by MENZEL, H. J, DIEPLINGER, H, LACKNER, C, HOPPICHLER, F, LLOYD, J. K, MULLER, D. R, LABEUR, C, TALMUD, P. J, UTERMANN, G

“…Patients with autosomal recessive abetalipoproteinemia (ABL) lack in their plasma all lipoproteins containing apolipoprotein (apo)B-100 or B-48. Previous…”
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Lipoprotein(a) quantified by an enzyme-linked immunosorbent assay with monoclonal antibodies by Labeur, C, Michiels, G, Bury, J, Usher, D C, Rosseneu, M

“…This new, sensitive, specific "sandwich"-type enzyme-linked immunosorbent assay (ELISA) for quantifying lipoprotein(a) [Lp(a)] in human serum and in…”
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