Search Results - "L. Wexler"

Dopamine agonists for the treatment of pituitary tumours: From ergot extracts to next generation therapies by Wexler, Tamara L., Page‐Wilson, Gabrielle

“…Dopamine agonists are a key tool in the therapeutic arsenal of endocrinologists worldwide. They exert their effects by binding to dopamine‐2 (D2) receptors…”
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Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors by Izumchenko, E., Paz, K., Ciznadija, D., Sloma, I., Katz, A., Vasquez-Dunddel, D., Ben-Zvi, I., Stebbing, J., McGuire, W., Harris, W., Maki, R., Gaya, A., Bedi, A., Zacharoulis, S., Ravi, R., Wexler, L.H., Hoque, M.O., Rodriguez-Galindo, C., Pass, H., Peled, N., Davies, A., Morris, R., Hidalgo, M., Sidransky, D.

“…While patient-derived xenografts (PDXs) offer a powerful modality for translational cancer research, a precise evaluation of how accurately patient responses…”
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New Collaborative Research on Suicide Prevention, Practice, and Policy With American Indian and Alaska Native Communities Holds Promise for All Peoples by Barlow, A., Haroz, E. E., O’Keefe, V. M., Brockie, T., Manson, S. M., Allen, J., Wexler, L., Buchwald, D., Rasmus, S., Goklish, N., Ivanich, J., Stifter, M., Cwik, M.

“…Youth suicide is increasing in the United States, with deaths among younger people of color driving this upward trend. For more than four decades, American…”
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Connectivity supporting attention in children with attention deficit hyperactivity disorder by Barber, Anita D, Jacobson, Lisa A, Wexler, Joanna L, Nebel, Mary Beth, Caffo, Brian S, Pekar, James J, Mostofsky, Stewart H

“…Intra-subject variability (ISV) is the most consistent behavioral deficit in Attention Deficit Hyperactivity Disorder (ADHD). ISV may be associated with…”
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Effects of growth hormone deficiency on body composition and biomarkers of cardiovascular risk after definitive therapy for acromegaly by Lin, E., Wexler, T. L., Nachtigall, L., Tritos, N., Swearingen, B., Hemphill, L., Loeffler, J., Biller, B. M. K., Klibanski, A., Miller, K. K.

“…Summary Background Both growth hormone (GH) excess and GH deficiency are associated with abnormalities in body composition and biomarkers of cardiovascular…”
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Late Toxicities of Intensity Modulated Radiation Therapy for Head and Neck Rhabdomyosarcoma by Lockney, N.A, Friedman, D.N, Wexler, L, Sklar, C, Casey, D.L, Wolden, S.L

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Sustaining suicide prevention programs in American Indian and Alaska Native communities and Tribal health centers by Haroz, E.E., Wexler, L., Manson, S.M., Cwik, M., O’Keefe, V.M., Allen, J., Rasmus, S.M., Buchwald, D., Barlow, A.

“…Background: Research on sustaining community-based interventions is limited. This is particularly true for suicide prevention programs and in American Indian…”
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Androgens in Women with Anorexia Nervosa and Normal-Weight Women with Hypothalamic Amenorrhea by Miller, K. K., Lawson, E. A., Mathur, V., Wexler, T. L., Meenaghan, E., Misra, M., Herzog, D. B., Klibanski, A.

“…Context: Anorexia nervosa and normal-weight hypothalamic amenorrhea are characterized by hypogonadism and hypercortisolemia. However, it is not known whether…”
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Neuroendocrine Disruptions Following Head Injury by Wexler, Tamara L.

“…Purpose of Review This article reviews hypopituitarism after TBI, the importance of pituitary hormones, and related controversies, concluding with a suggested…”
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Sleep apnea in 81 ambulatory male patients with stable heart failure : Types and their prevalences, consequences, and presentations by JAVAHERI, S, PARKER, T. J, LIMING, J. D, CORBETT, W. S, NISHIYAMA, H, WEXLER, L, ROSELLE, G. A

“…Heart failure is a highly prevalent disorder that continues to be associated with repeated hospitalizations, high morbidity, and high mortality. Sleep-related…”
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Seasonality of suicide behavior in Northwest Alaska: 1990–2009 by Silveira, M.L, Wexler, L, Chamberlain, J, Money, K, Spencer, R.M.C, Reich, N.G, Bertone-Johnson, E.R

“…Abstract Objectives Suicide is a leading cause of death worldwide, and disproportionately affects Indigenous populations. Seasonal suicide patterns are…”
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Prevention Conference V: Beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III by Greenland, P, Abrams, J, Aurigemma, G P, Bond, M G, Clark, L T, Criqui, M H, Crouse, 3rd, J R, Friedman, L, Fuster, V, Herrington, D M, Kuller, L H, Ridker, P M, Roberts, W C, Stanford, W, Stone, N, Swan, H J, Taubert, K A, Wexler, L

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Second malignancies after Ewing's sarcoma: radiation dose-dependency of secondary sarcomas by Kuttesch, Jr, J F, Wexler, L H, Marcus, R B, Fairclough, D, Weaver-McClure, L, White, M, Mao, L, Delaney, T F, Pratt, C B, Horowitz, M E, Kun, L E

“…An excess risk of second malignancies has been reported in survivors of Ewing's sarcoma. We examined a multiinstitutional data base to reevaluate the risk…”
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Effect of Theophylline on Sleep-Disordered Breathing in Heart Failure by Javaheri, S, Parker, T.J, Wexler, L, Liming, J.D, Lindower, P, Roselle, G.A

“…In most patients with the sleep apnea syndrome, episodes of apnea are due to obstruction of the upper airways (obstructive apnea). Application of nasal…”
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Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy by Mackall, Crystal L, Fleisher, Thomas A, Brown, Margaret R, Andrich, Mary P, Chen, Clara C, Feuerstein, Irwin M, Horowitz, Marc E, Magrath, Ian T, Shad, Aziza T, Steinberg, Seth M, Wexler, Leonard H, Gress, Ronald E

“…Depletion of CD4+ T lymphocytes is an important clinical problem in bone marrow transplantation 1 – 3 and human immunodeficiency virus (HIV) infection. 4 Yet…”
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Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin by Wexler, L H, Andrich, M P, Venzon, D, Berg, S L, Weaver-McClure, L, Chen, C C, Dilsizian, V, Avila, N, Jarosinski, P, Balis, F M, Poplack, D G, Horowitz, M E

“…We conducted an open-label, randomized trial to determine whether ICRF-187 would reduce doxorubicin-induced cardiotoxicity in pediatric sarcoma patients…”
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A case report of concurrent embryonal rhabdomyosarcoma and diffuse large B-cell lymphoma in an adult without identifiable cancer predisposition by Mathias, M D, Ortiz, M V, Magnan, H, Ambati, S R, Slotkin, E K, Chou, A J, Walsh, M F, Offit, K, Moskowitz, C, Kentsis, A, Wexler, L H

“…Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin lymphoma. Rhabdomyosarcoma, the most common soft tissue sarcoma of childhood…”
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Altered Trafficking of Mutant Connexin32 by Deschenes, Suzanne M, Walcott, Jessica L, Wexler, Tamara L, Scherer, Steven S, Fischbeck, Kenneth H

“…We examined the cellular localization of nine different connexin32 (Cx32) mutants associated with X-linked Charcot-Marie-Tooth disease (CMTX) in…”
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Relation of Gemfibrozil Treatment and Lipid Levels With Major Coronary Events: VA-HIT: A Randomized Controlled Trial by Robins, Sander J, Collins, Dorothea, Wittes, Janet T, Papademetriou, Vasilios, Deedwania, Prakash C, Schaefer, Ernst J, McNamara, Judith R, Kashyap, Moti L, Hershman, Jerome M, Wexler, Laura F, Rubins, Hanna Bloomfield, for the VA-HIT Study Group

“…CONTEXT A low plasma level of high-density lipoprotein cholesterol (HDL-C) is a major risk factor for coronary heart disease (CHD). A secondary prevention…”
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Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalance after intensive chemotherapy by MACKALL, C. L, FLEISHER, T. A, BROWN, M. R, ANDRICH, M. P, CHEN, C. C, FEUERSTEIN, I. M, MAGRATH, I. T, WEXLER, L. H, DIMITROV, D. S, GRESS, R. E

“…Rapid recovery of CD4+ T cells after intensive chemotherapy is limited by an age-dependent decline in thymopoiesis. Here we sought to determine whether similar…”
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