Search Results - "L. Fields"

The Doctor's Dilemma: Opiate Analgesics and Chronic Pain by Fields, Howard L.

“…Opiates are utilized routinely and effectively as a short-term analgesic treatment for a variety of acute pain conditions such as occur following trauma, and…”
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Board quality and the cost of debt capital: The case of bank loans by Paige Fields, L., Fraser, Donald R., Subrahmanyam, Avanidhar

“…► We show that firms with higher quality boards borrow at lower rates. ► This relation exists after controls for ownership structure and CEO compensation. ► We…”
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Identification of rat ventral tegmental area GABAergic neurons by Margolis, Elyssa B, Toy, Brian, Himmels, Patricia, Morales, Marisela, Fields, Howard L

“…The canonical two neuron model of opioid reward posits that mu opioid receptor (MOR) activation produces reward by disinhibiting midbrain ventral tegmental…”
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Predicting Value of Pain and Analgesia: Nucleus Accumbens Response to Noxious Stimuli Changes in the Presence of Chronic Pain by Baliki, Marwan N., Geha, Paul Y., Fields, Howard L., Apkarian, A. Vania

“…We compared brain activations in response to acute noxious thermal stimuli in controls and chronic back pain (CBP) patients. Pain perception and related…”
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Ventral tegmental area glutamate neurons: electrophysiological properties and projections by Hnasko, Thomas S, Hjelmstad, Gregory O, Fields, Howard L, Edwards, Robert H

“…The ventral tegmental area (VTA) has a central role in the neural processes that underlie motivation and behavioral reinforcement. Although thought to contain…”
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Basolateral Amygdala Neurons Facilitate Reward-Seeking Behavior by Exciting Nucleus Accumbens Neurons by Ambroggi, Frederic, Ishikawa, Akinori, Fields, Howard L., Nicola, Saleem M.

“…Both the nucleus accumbens (NAc) and basolateral amygdala (BLA) contribute to learned behavioral choice. Neurons in both structures that encode…”
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Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain by Navratilova, Edita, Xie, Jennifer Yanhua, Meske, Diana, Qu, Chaoling, Morimura, Kozo, Okun, Alec, Arakawa, Naohisa, Ossipov, Michael, Fields, Howard L, Porreca, Frank

“…Pain is aversive, and its relief elicits reward mediated by dopaminergic signaling in the nucleus accumbens (NAc), a part of the mesolimbic reward motivation…”
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Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry by Navratilova, Edita, Xie, Jennifer Y., Okun, Alec, Qu, Chaoling, Eyde, Nathan, Ci, Shuang, Ossipov, Michael H., King, Tamara, Fields, Howard L., Porreca, Frank

“…Relief of pain is rewarding. Using a model of experimental postsurgical pain we show that blockade of afferent input from the injury with local anesthetic…”
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Roles of nucleus accumbens core and shell in incentive-cue responding and behavioral inhibition by Ambroggi, Frederic, Ghazizadeh, Ali, Nicola, Saleem M, Fields, Howard L

“…The nucleus accumbens (NAc) is involved in many reward-related behaviors. The NAc has two major components, the core and the shell. These two areas have…”
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Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? by Oaklander, Anne Louise, Fields, Howard L.

“…Neurologist S. Weir Mitchell first described “causalgia” following wartime nerve injury, with its persistent distal limb burning pain, swelling, and abnormal…”
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Mu Opioid Receptor Actions in the Lateral Habenula by Margolis, Elyssa B, Fields, Howard L

“…Increased activity of lateral habenula (LHb) neurons is correlated with aversive states including pain, opioid abstinence, rodent models of depression, and…”
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Unmasking the tonic-aversive state in neuropathic pain by Vera-Portocarrero, Louis, Vanderah, Todd W, Dussor, Gregory, Lai, Josephine, Porreca, Frank, King, Tamara, Gutierrez, Tannia, Fields, Howard L

“…Tonic pain has been difficult to demonstrate in animals. Because relief of pain is rewarding, analgesic agents that are not rewarding in the absence of pain…”
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Ventral Pallidum Neurons Encode Incentive Value and Promote Cue-Elicited Instrumental Actions by Richard, Jocelyn M., Ambroggi, Frederic, Janak, Patricia H., Fields, Howard L.

“…The ventral pallidum (VP) is posited to contribute to reward seeking by conveying upstream signals from the nucleus accumbens (NAc). Yet, very little is known…”
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Sensitivity potential to a light flavor-changing scalar boson with DUNE and NA64μ by Radics, B., Molina-Bueno, L., Fields, L., Sieber, H., Crivelli, P.

“…In this work, we report on the sensitivity potential of complementary muon-on-target experiments to new physics using a scalar boson benchmark model associated…”
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The Rostromedial Tegmental Nucleus (RMTg), a GABAergic Afferent to Midbrain Dopamine Neurons, Encodes Aversive Stimuli and Inhibits Motor Responses by Jhou, Thomas C., Fields, Howard L., Baxter, Mark G., Saper, Clifford B., Holland, Peter C.

“…Separate studies have implicated the lateral habenula (LHb) or amygdala-related regions in processing aversive stimuli, but their relationships to each other…”
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Orexin A in the VTA Is Critical for the Induction of Synaptic Plasticity and Behavioral Sensitization to Cocaine by Borgland, Stephanie L., Taha, Sharif A., Sarti, Federica, Fields, Howard L., Bonci, Antonello

“…Dopamine neurons in the ventral tegmental area (VTA) represent a critical site of synaptic plasticity induced by addictive drugs. Orexin/hypocretin-containing…”
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Alcohol consumption induces endogenous opioid release in the human orbitofrontal cortex and nucleus accumbens by Mitchell, Jennifer M, O'Neil, James P, Janabi, Mustafa, Marks, Shawn M, Jagust, William J, Fields, Howard L

“…Excessive consumption of alcohol is among the leading causes of preventable death worldwide. Although ethanol modulates a variety of molecular targets,…”
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Ventral tegmental area neurons in learned appetitive behavior and positive reinforcement by FIELDS, Howard L, HJELMSTAD, Gregory O, MARGOLIS, Elyssa B, NICOLA, Saleem M

“…Ventral tegmental area (VTA) neuron firing precedes behaviors elicited by reward-predictive sensory cues and scales with the magnitude and unpredictability of…”
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Mu-opioid receptor activation in the medial shell of nucleus accumbens promotes alcohol consumption, self-administration and cue-induced reinstatement by Richard, Jocelyn M., Fields, Howard L.

“…Endogenous opioid signaling in ventral cortico-striatal-pallidal circuitry is implicated in elevated alcohol consumption and relapse to alcohol seeking…”
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Cortico-Accumbens Regulation of Approach-Avoidance Behavior Is Modified by Experience and Chronic Pain by Schwartz, Neil, Miller, Catriona, Fields, Howard L.

“…Although optimizing decisions between drives to avoid pain and to obtain reward are critical for survival, understanding the neuronal circuit activity that…”
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