Search Results - "L. Burt, Justin"

Small-Volume Continuous Manufacturing of Merestinib. Part 1. Process Development and Demonstration by Cole, Kevin P, Reizman, Brandon J, Hess, Molly, Groh, Jennifer M, Laurila, Michael E, Cope, Richard F, Campbell, Bradley M, Forst, Mindy B, Burt, Justin L, Maloney, Todd D, Johnson, Martin D, Mitchell, David, Polster, Christopher S, Mitra, Aurpon W, Boukerche, Moussa, Conder, Edward W, Braden, Timothy M, Miller, Richard D, Heller, Michael R, Phillips, Joseph L, Howell, John R

“…Development of a small volume continuous process that used a combination of batch and flow unit operations to manufacture the small molecule oncolytic…”
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Interaction of silver nanoparticles with HIV-1 by Elechiguerra, Jose Luis, Burt, Justin L, Morones, Jose R, Camacho-Bragado, Alejandra, Gao, Xiaoxia, Lara, Humberto H, Yacaman, Miguel Jose

“…The interaction of nanoparticles with biomolecules and microorganisms is an expanding field of research. Within this field, an area that has been largely…”
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Small-Volume Continuous Manufacturing of Merestinib. Part 2. Technology Transfer and cGMP Manufacturing by Reizman, Brandon J, Cole, Kevin P, Hess, Molly, Burt, Justin L, Maloney, Todd D, Johnson, Martin D, Laurila, Michael E, Cope, Richard F, Luciani, Carla V, Buser, Jonas Y, Campbell, Bradley M, Forst, Mindy B, Mitchell, David, Braden, Timothy M, Lippelt, Christopher K, Boukerche, Moussa, Starkey, Derek R, Miller, Richard D, Chen, Jing, Sun, Baoquan, Kwok, Martin, Zhang, Xin, Tadayon, Sam, Huang, Ping

“…Technology transfer of a small volume continuous (SVC) process and Current Good Manufacturing Practices (cGMP) manufacturing of merestinib are described. A…”
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Data-Driven Prediction of Risk in Drug Substance Starting Materials by Reizman, Brandon J, Burt, Justin L, Frank, Scott A, Argentine, Mark D, Garcia-Muñoz, Salvador

“…Regulatory approval for drug substance (DS) starting materials (SMs) represents a significant milestone in the progression toward approval of the proposed DS…”
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Noble-Metal Nanoparticles Directly Conjugated to Globular Proteins by Burt, Justin L, Gutiérrez-Wing, Claudia, Miki-Yoshida, Mario, José-Yacamán, Miguel

“…We report the synthesis of gold nanoparticles directly conjugated to bovine serum albumin protein by chemical reduction in aqueous solution. Transmission…”
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Beyond Archimedean solids: Star polyhedral gold nanocrystals by Burt, Justin L., Elechiguerra, Jose L., Reyes-Gasga, Jose, Martin Montejano-Carrizales, J., Jose-Yacaman, Miguel

“…We report star polyhedral gold nanocrystals synthesized by colloidal reduction with ascorbic acid in water at ambient conditions. We identify two distinct…”
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Model-Guided Design Space Development for a Drug Substance Manufacturing Process by L. Burt, Justin, D. Braem, Alan, Ramirez, Antonio, Mudryk, Boguslaw, Rossano, Lucius, Tummala, Srinivas

“…This case study outlines an application of quality by design principles to a drug substance manufacturing process. A hybrid process chemistry model consisting…”
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Bacterial Biosynthesis of Cadmium Sulfide Nanocrystals by Sweeney, Rozamond Y., Mao, Chuanbin, Gao, Xiaoxia, Burt, Justin L., Belcher, Angela M., Georgiou, George, Iverson, Brent L.

“…Semiconductor nanocrystals, which have unique optical and electronic properties, have potential for applications in the emerging field of nanoelectronics. To…”
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Influence of morphology in the catalytic activity of bioconjugated platinum nanostructures by Guerra, Javier, Burt, Justin L., Ferrer, Domingo A., Mejía, Sergio, José-Yacamán, Miguel

“…Platinum nanoparticles stabilized by a protein, bovine serum albumin, have been synthesized successfully with two different morphologies such as cuboctahedra…”
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Selection and Scale-Up Evaluation of an Alternative Route to (−)-(3R,4R)‑1-Benzyl-4-(benzylamino)piperidin-3-ol by Young, Ian S, Ortiz, Adrian, Sawyer, James R, Conlon, David A, Buono, Frederic G, Leung, Simon W, Burt, Justin L, Sortore, Eric W

“…An efficient, scalable synthesis of (−)-(3R,4R)-1-benzyl-4-(benzylamino)piperidin-3-ol (4) is described. Reduction of the pyridinium salt prepared from…”
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Development of a Scalable Process for the Synthesis of Cyclopropyl-Methyl-Proline with Complex Stereochemistry: A Key Building Block of Factor D Inhibitors by Hashimoto, Akihiro, Ferretti, Antonio C., Tipparaju, Suresh K., Burt, Justin L., Soman, Ashish, Phadke, Avinash, Chandran, Prabu, Lahoti, Anand M., Bilidegalu N, Devaraju, Mani, Anbazhagan, Datta, Swarup, Rai, Sankappa, Huddar, Sameerana, Kumara, Prasanna, Raju, Tirumani, AN, Guruprasad, Ganapathy, Suman, Chukka, Tanish

“…The development of a scalable process for a complex intermediate featuring a chiral, quaternary cyclopropane moiety presented significant challenges. We report…”
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