Search Results - "L. Appel"
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Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss
Published in Diabetologia (01-02-2012)“…Aims/hypothesis Insulin resistance (IR) improves with weight loss, but this response is heterogeneous. We hypothesised that metabolomic profiling would…”
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2
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33
Published in Nature communications (05-02-2021)“…Dynamic regulation of intestinal cell differentiation is crucial for both homeostasis and the response to injury or inflammation. Sprouty2, an intracellular…”
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3
Does vaginal delivery mitigate or strengthen the intergenerational association of overweight and obesity? Findings from the Boston Birth Cohort
Published in International Journal of Obesity (01-04-2017)“…Background/Objectives: The intergenerational association of obesity may be driven by mother-to-newborn transmission of microbiota at birth. Yet cesarean…”
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GParareal: a time-parallel ODE solver using Gaussian process emulation
Published in Statistics and computing (01-02-2023)“…Sequential numerical methods for integrating initial value problems (IVPs) can be prohibitively expensive when high numerical accuracy is required over the…”
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5
Polyphenols as dietary supplements: A double-edged sword
Published in Nutrition and dietary supplements (01-01-2010)“…Increased consumption of fruits and vegetables is associated with a lower risk of chronic disease such as cardiovascular disease, some forms of cancer, and…”
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Effects of dietary carbohydrate on 1,5‐anhydroglucitol in a population without diabetes: results from the OmniCarb trial
Published in Diabetic medicine (01-10-2017)“…Aims To determine the effects of dietary changes in amount and type of carbohydrate on 1,5‐anhydroglucitol levels. Methods We conducted an ancillary study to a…”
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Web-Based Video Education to Improve Uptake of Influenza Vaccination and Other Preventive Health Recommendations in Adults With Inflammatory Bowel Disease: Randomized Controlled Trial of Project PREVENT
Published in Journal of medical Internet research (23-08-2023)“…Background Patients with inflammatory bowel disease (IBD) are at increased risk of infections, bone fractures, and skin cancers. Objective We developed…”
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8
Using passive acoustic monitoring to estimate northern spotted owl landscape use and pair occupancy
Published in Ecosphere (Washington, D.C) (01-02-2023)“…Managing forests for biodiversity conservation while maintaining economic output is a major challenge globally and requires accurate and timely monitoring of…”
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Effects of the DASH diet on blood pressure in patients with and without metabolic syndrome: results from the DASH trial
Published in Journal of human hypertension (01-03-2014)“…In the Dietary Approach to Stop Hypertension (DASH) trial, the DASH diet reduced blood pressure (BP) in a diverse sample of US adults. Subsequent analyses of…”
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10
Representative volume element for parallel fiber bundles: Model and size convergence
Published in Composites. Part A, Applied science and manufacturing (01-08-2016)“…The simulation of textiles often occurs at the meso scale, where the individual tows are treated as a homogeneous continuum. To properly utilize such models,…”
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Workflow and convolutional neural network for automated identification of animal sounds
Published in Ecological indicators (01-05-2021)“…•We developed a deep neural network to identify sounds made by 14 animal species.•We built an efficient pipeline for processing large amounts of audio.•Output…”
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12
behavioral weight-loss intervention for persons with serious mental illness in psychiatric rehabilitation centers
Published in International Journal of Obesity (01-08-2011)“…Objective: Overweight and obesity are epidemic in populations with serious mental illnesses. We developed and pilot-tested a behavioral weight-loss…”
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13
Minding the gap: towards a shared clinical reasoning lexicon across the pre-clerkship/clerkship transition
Published in Medical education online (31-12-2024)“…Teaching and learning of clinical reasoning are core principles of medical education. However, little guidance exists for faculty leaders to navigate…”
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14
The effects of dietary patterns on plasma renin activity: results from the Dietary Approaches to Stop Hypertension trial
Published in Journal of human hypertension (01-11-2012)“…A diet rich in fruits, vegetables and low-fat dairy products, and reduced in saturated fat, total fat and cholesterol (the ‘DASH’ diet) significantly lowers…”
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Effect of lifestyle modifications on blood pressure by race, sex, hypertension status, and age
Published in Journal of human hypertension (01-01-2005)“…Recommendations for control of high blood pressure (BP) emphasize lifestyle modification, including weight loss, reduced sodium intake, increased physical…”
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Experimental characterization of single ply out‐of‐plane permeability through gaseous flow
Published in Polymer composites (01-09-2018)“…A new approach to measure out‐of‐plane permeability of single ply unidirectional fiber material under tensile load has been investigated. Single ply…”
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17
Long-term Weight loss and changes in blood pressure : Results of the Trials of Hypertension prevention, phase II
Published in Annals of internal medicine (02-01-2001)“…Weight loss appears to be an effective method for primary prevention of hypertension. However, the long-term effects of weight loss on blood pressure have not…”
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The effects of the DASH dietary pattern on clinical outcomes and quality of life in adults with uncontrolled asthma: Design and methods of the ALOHA Trial
Published in Contemporary clinical trials (01-08-2023)“…Poor diet quality is an important risk factor for increased asthma prevalence and poor asthma control. To address the question of whether adults with asthma…”
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Regulation and Function of Epithelial Secreted Phospholipase A2 Group X in Asthma
Published in American journal of respiratory and critical care medicine (01-07-2013)“…Indirect airway hyperresponsiveness (AHR) is a fundamental feature of asthma that is manifest as exercise-induced bronchoconstriction (EIB). Secreted…”
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20
Serotonin synthesis rate and the tryptophan hydroxylase-2: G-703T polymorphism in social anxiety disorder
Published in Journal of psychopharmacology (Oxford) (01-10-2016)“…It is disputed whether anxiety disorders, like social anxiety disorder, are characterized by serotonin over- or underactivity. Here, we evaluated whether our…”
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