Search Results - "L Onions, Karen"

VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy by Onions, Karen L, Gamez, Monica, Buckner, Nicola R, Baker, Siân L, Betteridge, Kai B, Desideri, Sara, Dallyn, Benjamin P, Ramnath, Raina D, Neal, Chris R, Farmer, Louise K, Mathieson, Peter W, Gnudi, Luigi, Alitalo, Kari, Bates, David O, Salmon, Andrew H J, Welsh, Gavin I, Satchell, Simon C, Foster, Rebecca R

“…Elevated levels of vascular endothelial growth factor (VEGF) A are thought to cause glomerular endothelial cell (GEnC) dysfunction and albuminuria in diabetic…”
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Correction: Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes by Gamez, Monica, E Elhegni, Hesham, Fawaz, Sarah, Ho Ho, Kwan, W Campbell, Neill, A Copland, David, L Onions, Karen, J Butler, Matthew, J Wasson, Elizabeth, Crompton, Michael, D Ramnath, Raina, Qiu, Yan, Yamaguchi, Yu, P Arkill, Kenton, O Bates, David, E Turnbull, Jeremy, V Zubkova, Olga, I Welsh, Gavin, Atan, Denize, C Satchell, Simon, R Foster, Rebecca

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Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes by Gamez, Monica, Elhegni, Hesham E, Fawaz, Sarah, Ho, Kwan Ho, Campbell, Neill W, Copland, David A, Onions, Karen L, Butler, Matthew J, Wasson, Elizabeth J, Crompton, Michael, Ramnath, Raina D, Qiu, Yan, Yamaguchi, Yu, Arkill, Kenton P, Bates, David O, Turnbull, Jeremy E, Zubkova, Olga V, Welsh, Gavin I, Atan, Denize, Satchell, Simon C, Foster, Rebecca R

“…Diabetes mellitus is a chronic disease which is detrimental to cardiovascular health, often leading to secondary microvascular complications, with huge global…”
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Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx by Crompton, Michael, Ferguson, Joanne K, Ramnath, Raina D, Onions, Karen L, Ogier, Anna S, Gamez, Monica, Down, Colin J, Skinner, Laura, Wong, Kitty H, Dixon, Lauren K, Sutak, Judit, Harper, Steven J, Pontrelli, Paola, Gesualdo, Loreto, Heerspink, Hiddo L, Toto, Robert D, Welsh, Gavin I, Foster, Rebecca R, Satchell, Simon C, Butler, Matthew J

“…The glomerular endothelial glycocalyx (GEnGlx) forms the first part of the glomerular filtration barrier. Previously, we showed that mineralocorticoid receptor…”
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Aldosterone induces albuminuria via matrix metalloproteinase-dependent damage of the endothelial glycocalyx by Butler, Matthew J, Ramnath, Raina, Kadoya, Hiroyuki, Desposito, Dorinne, Riquier-Brison, Anne, Ferguson, Joanne K, Onions, Karen L, Ogier, Anna S, ElHegni, Hesham, Coward, Richard J, Welsh, Gavin I, Foster, Rebecca R, Peti-Peterdi, Janos, Satchell, Simon C

“…Aldosterone contributes to end-organ damage in heart failure and chronic kidney disease. Mineralocorticoid-receptor inhibitors limit activation of the receptor…”
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Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease by Ramnath, Raina D, Butler, Matthew J, Newman, Georgina, Desideri, Sara, Russell, Amy, Lay, Abigail C, Neal, Chris R, Qiu, Yan, Fawaz, Sarah, Onions, Karen L, Gamez, Monica, Crompton, Michael, Michie, Chris, Finch, Natalie, Coward, Richard J, Welsh, Gavin I, Foster, Rebecca R, Satchell, Simon C

“…The endothelial glycocalyx is a key component of the glomerular filtration barrier. We have shown that matrix metalloproteinase (MMP)-mediated syndecan 4…”
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A novel assay provides sensitive measurement of physiologically relevant changes in albumin permeability in isolated human and rodent glomeruli by Desideri, Sara, Onions, Karen L, Qiu, Yan, Ramnath, Raina D, Butler, Matthew J, Neal, Christopher R, King, Matthew L R, Salmon, Andrew E, Saleem, Moin A, Welsh, Gavin I, Michel, C Charles, Satchell, Simon C, Salmon, Andrew H J, Foster, Rebecca R

“…Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. Here we describe a…”
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Endothelial glycocalyx restoration by growth factors in diabetic nephropathy by Desideri, Sara, Onions, Karen L, Baker, Siân L, Gamez, Monica, El Hegni E Hussien, Hesham, Russell, Amy, Satchell, Simon C, Foster, Rebecca R

“…The endothelial glycocalyx (eGlx) constitutes the first barrier to protein in all blood vessels. This is particularly noteworthy in the renal glomerulus, an…”
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Glomerular Endothelial Glycocalyx Damage Occurs in Human Diabetic Nephropathy and Could Be Prevented by Early Mineralocorticoid Receptor Inhibition: PO0893 by Crompton, Michael, Butler, Matthew J., Onions, Karen L., Ogier, Anna S., Welsh, Gavin I., Foster, Rebecca R., Satchell, Simon C.

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The Authors Reply by Desideri, Sara, Onions, Karen L, Butler, Matthew J, Michel, C Charles, Satchell, Simon C, Salmon, Andrew H J, Foster, Rebecca R

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