Search Results - "Lüttges, J"

Does anyone survive pancreatic ductal adenocarcinoma? A nationwide study re-evaluating the data of the Finnish Cancer Registry by Carpelan-Holmström, M, Nordling, S, Pukkala, E, Sankila, R, Lüttges, J, Klöppel, G, Haglund, C

“…Background: Worldwide survival data for ductal adenocarcinoma of the pancreas are the lowest among the 60 most frequent types of organ cancers. Hence published…”
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European experts consensus statement on cystic tumours of the pancreas by Del Chiaro, Marco, Verbeke, Caroline, Salvia, Roberto, Klöppel, Gunter, Werner, Jens, McKay, Colin, Friess, Helmut, Manfredi, Riccardo, Van Cutsem, Eric, Löhr, Matthias, Segersvärd, Ralf

“…Abstract Cystic lesions of the pancreas are increasingly recognized. While some lesions show benign behaviour (serous cystic neoplasm), others have an…”
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Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal by KOSMAHL, M, PAUSER, U, PETERS, K, SIPOS, B, LÜTTGES, J, KREMER, B, KLÖPPEL, G

“…Although cystic neoplasms and lesions of the pancreas are rare, they have attracted a great deal of attention because of their potential curability. Since, in…”
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The mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas by LÜTTGES, J, FEYERABEND, B, BUCHELT, T, PACENA, M, KLÖPPEL, G

“…Recently, it was shown that ductal adenocarcinomas and intraductal papillary-mucinous neoplasms of the pancreas differ in their expression of the mucin markers…”
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Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions by HRUBAN, Ralph H, ADSAY, N. Volkan, LÜTTGES, Jutta, OFFERHAUS, G. Johan A, ALBORES-SAAVEDRA, Jorge, COMPTON, Carolyn, GARRETT, Elizabeth S, GOODMAN, Steven N, KERN, Scott E, KLIMSTRA, David S, KLÖPPEL, Günter, LONGNECKER, Daniel S

“…Proliferative epithelial lesions in the smaller caliber pancreatic ducts and ductules have been the subject of numerous morphologic, clinical, and genetic…”
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DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma by MAACKE, H, JOST, K, OPITZ, S, MISKA, S, YUAN, Y, HASSELBACH, L, LÜTTGES, J, KALTHOFF, H, STÜRZBECHER, H.-W

“…Molecular processes that could contribute to differences in chemo- and radioresistance include variations in DNA repair mechanisms. In mammalian cells, the…”
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Non-alcoholic duct destructive chronic pancreatitis by Ectors, N, Maillet, B, Aerts, R, Geboes, K, Donner, A, Borchard, F, Lankisch, P, Stolte, M, Lüttges, J, Kremer, B, Klöppel, G

“…Background—The pathology of non-alcoholic chronic pancreatitis has not yet been sufficiently studied. Aims—To identify the major changes of pancreatic tissue…”
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ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma by GRÜTZMANN, R, LÜTTGES, J, SCHACKERT, H. K, SAEGER, H. D, KLÖPPEL, G, PILARSKY, C, SIPOS, B, AMMERPOHL, O, DOBROWOLSKI, F, ALLDINGER, I, KERSTING, S, OCKERT, D, KOCH, R, KALTHOFF, H

“…Gene expression profiling revealed ADAM9 to be distinctly overexpressed in pancreatic ductal adenocarcinoma (PDAC). We examined the relevance of ADAM9…”
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Allelic Loss Is Often the First Hit in the Biallelic Inactivation of the p53 and DPC4 Genes During Pancreatic Carcinogenesis by Lüttges, Jutta, Galehdari, Hamid, Bröcker, Verena, Schwarte-Waldhoff, Irmgard, Henne-Bruns, Doris, Klöppel, Günter, Schmiegel, Wolff, Hahn, Stephan A.

“…The presumed precursor lesions of pancreatic ductal adenocarcinoma were recently classified according to their increasing grade of dysplasia and were…”
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Smad4/DPC4-Mediated Tumor Suppression through Suppression of Angiogenesis by Schwarte-Waldhoff, Irmgard, Volpert, Olga V., Bouck, Noel P., Sipos, Bence, Hahn, Stephan A., Klein-Scory, Susanne, Luttges, Jutta, Kloppel, Gunter, Graeven, Ulrich, Eilert-Micus, Christina, Hintelmann, Annette, Schmiegel, Wolff

“…Smad4/DPC4 (deleted in pancreatic carcinoma, locus 4) is a tumor suppressor gene lost at high frequency in cancers of the pancreas and other gastrointestinal…”
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Duct changes and K-ras mutations in the disease-free pancreas : analysis of type, age relation and spatial distribution by LÜTTGES, J, REINECKE-LÜTHGE, A, MÖLLMANN, B, MENKE, M. A. O. H, CLEMENS, A, KLIMPFINGER, M, SIPOS, B, KLÖPPEL, G

“…Recent molecular studies have suggested that hyperplastic duct lesions of the pancreas are potential precursors of pancreatic ductal carcinoma. This study…”
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The retroperitoneal resection margin and vessel involvement are important factors determining survival after pancreaticoduodenectomy for ductal adenocarcinoma of the head of the pancreas by LÜTTGES, J, VOGEL, I, MENKE, M, HENNE-BRUNS, D, KREMER, B, KLÖPPEL, G

“…The prognosis of ductal adenocarcinoma of the pancreas is still poor. We analysed the factors that have a major influence on the survival of patients. Surgical…”
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Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics by Ruschoff, J, Dietmaier, W, Luttges, J, Seitz, G, Bocker, T, Zirngibl, H, Schlegel, J, Schackert, HK, Jauch, KW, Hofstaedter, F

“…Clinicopathological evidence has accumulated that colorectal adenocarcinoma with minimal or no glandular differentiation constitutes two entities with…”
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Solitary fibrous tumour of the pancreas : a new member of the small group of mesenchymal pancreatic tumours by LÜTTGES, J, MENTZEL, T, HÜBNER, G, KLÖPPEL, G

“…Solitary fibrous tumours usually occur in the pleura, but occasionally they appear in extraserosal soft tissues or parenchymatous organs, where their diagnosis…”
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WHO-classification 2000: exocrine pancreatic tumors by Klöppel, G, Lüttges, J

“…The new WHO-classification is more than a histological description of the tumors of the exocrine pancreas. It is a clinicopathological overview that also…”
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Primary squamous cell carcinoma of the stomach. Report of a case and review of literature by Schmidt, C, Schmid, A, Lüttges, J E, Kremer, B, Henne-Bruns, D

“…Primary squamous cell carcinomas of the stomach represent a rare entity. Since the first report in 1895 by Rörig et al. (1) only 80 cases have been published…”
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Update on the pathology and genetics of exocrine pancreatic tumors with ductal phenotype: precursor lesions and new tumor entities by Lüttges, J, Klöppel, G

“…The majority of pancreatic neoplasms show a ductal phenotype and can be classified as ductal adenocarcinomas. Pancreatic duct lesions have been discussed as…”
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New strategies and designs in pancreatic cancer research: consensus guidelines report from a European expert panel by Van Laethem, J.-L., Verslype, C., Iovanna, J.L., Michl, P., Conroy, T., Louvet, C., Hammel, P., Mitry, E., Ducreux, M., Maraculla, T., Uhl, W., Van Tienhoven, G., Bachet, J.B., Maréchal, R., Hendlisz, A., Bali, M., Demetter, P., Ulrich, F., Aust, D., Luttges, J., Peeters, M., Mauer, M., Roth, A., Neoptolemos, J.P., Lutz, M.

“…Although the treatment of pancreatic ductal adenocarcinoma (PDAC) remains a huge challenge, it is entering a new era with the development of new strategies and…”
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The expression of OX40 in immunologically mediated diseases of the gastrointestinal tract (celiac disease, Crohn's disease, ulcerative colitis) by Stüber, E, Büschenfeld, A, Lüttges, J, Von Freier, A, Arendt, T, Fölsch, U R

“…Background The membrane bound receptor OX40 (CD134) — a member of the TNF‐R/NGF‐R superfamily — is expressed on activated CD4+‐T cells in humans and rodents…”
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Surgical possibilities for pancreatic cancer : Extended resection by KREMER, B, VOGEL, I, LÜTTGES, J, KLÖPPEL, G, HENNE-BRUNS, D

“…It was the aim of this study to investigate the influence of extended retroperitoneal tissue clearance on long-term survival in patients with ductal…”
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