Search Results - "Lüttgau, Sandra"
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Therapeutic Potential of Amanitin-Conjugated Anti-Epithelial Cell Adhesion Molecule Monoclonal Antibody Against Pancreatic Carcinoma
Published in JNCI : Journal of the National Cancer Institute (18-04-2012)“…Human epithelial cell adhesion molecule (EpCAM) is overexpressed in many cancers. Anti-EpCAM antibodies have shown promise in preclinical studies, but showed…”
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Immunotherapy of B-Cell Lymphoma with an Engineered Bispecific Antibody Targeting CD19 and CD5
Published in Antibodies (Basel) (01-06-2013)“…Using genetic engineering a humanized Fab fragment with specificity for CD19 was fused to a disulfide-stabilized single-chain antibody (dsFv) recognizing CD5…”
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T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice
Published in Journal of hepatology (01-11-2021)“…Current antiviral therapies control but rarely eliminate HBV, leaving chronic HBV carriers at risk of developing hepatocellular carcinoma (HCC). Lacking or…”
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Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma
Published in Cancer research (Chicago, Ill.) (15-03-2010)“…Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression. Functionally, L1CAM promotes tumor cell invasion and motility,…”
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