Search Results - "Lüttgau, Sandra"

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    Therapeutic Potential of Amanitin-Conjugated Anti-Epithelial Cell Adhesion Molecule Monoclonal Antibody Against Pancreatic Carcinoma by MOLDENHAUER, Gerhard, SALNIKOV, Alexei V, LÜTTGAU, Sandra, HERR, Ingrid, ANDERL, Jan, FAULSTICH, Heinz

    “…Human epithelial cell adhesion molecule (EpCAM) is overexpressed in many cancers. Anti-EpCAM antibodies have shown promise in preclinical studies, but showed…”
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    Journal Article
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    Immunotherapy of B-Cell Lymphoma with an Engineered Bispecific Antibody Targeting CD19 and CD5 by Lüttgau, Sandra, Deppe, Dorothée, Meyer, Saskia, Fertig, Regina, Panjideh, Hossein, Lipp, Martin, Schmetzer, Oliver, Pezzutto, Antonio, Breitling, Frank, Moldenhauer, Gerhard

    Published in Antibodies (Basel) (01-06-2013)
    “…Using genetic engineering a humanized Fab fragment with specificity for CD19 was fused to a disulfide-stabilized single-chain antibody (dsFv) recognizing CD5…”
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    Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma by Wolterink, Silke, Moldenhauer, Gerhard, Fogel, Mina, Kiefel, Helena, Pfeifer, Marco, Lüttgau, Sandra, Gouveia, Ricardo, Costa, Julia, Endell, Jan, Moebius, Ulrich, Altevogt, Peter

    Published in Cancer research (Chicago, Ill.) (15-03-2010)
    “…Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression. Functionally, L1CAM promotes tumor cell invasion and motility,…”
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    Journal Article
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